• Thumbnail for Phosphatidylinositol transfer protein, alpha
    Phosphatidylinositol transfer protein alpha isoform is a protein that in humans is encoded by the PITPNA gene. Phosphatidylinositol transfer proteins...
    1 KB (152 words) - 21:05, 13 October 2022
  • Thumbnail for Phosphatidylinositol transfer protein
    Phosphatidylinositol transfer protein (PITP) or priming in exocytosis protein 3 (PEP3) is a ubiquitous cytosolic domain involved in transport of phospholipids...
    4 KB (406 words) - 03:13, 29 November 2023
  • Thumbnail for Phosphatidylinositol
    Phosphatidylinositol or inositol phospholipid is a biomolecule. It was initially called "inosite" when it was discovered by Léon Maquenne and Johann Joseph...
    20 KB (2,009 words) - 05:00, 2 March 2024
  • Thumbnail for Peripheral membrane protein
    activator proteins CRAL-TRIO domain (α-Tocopherol and phosphatidylinositol sec14p transfer proteins) Sterol carrier proteins Phosphatidylinositol transfer proteins...
    55 KB (4,391 words) - 16:59, 23 March 2024
  • alpha-1 (α1) adrenergic receptors are G protein-coupled receptors (GPCRs) associated with the Gq heterotrimeric G protein. α1-adrenergic receptors are...
    16 KB (1,528 words) - 12:39, 26 November 2023
  • Thumbnail for Phosphatidylinositol 4,5-bisphosphate
    important signaling proteins. PIP2 also forms lipid clusters that sort proteins. PIP2 is formed primarily by the type I phosphatidylinositol 4-phosphate 5-kinases...
    21 KB (2,097 words) - 14:31, 7 June 2024
  • Thumbnail for Protein primary structure
    phosphatidylinositol (GPI) attachment Glycosyl phosphatidylinositol(GPI) is a large, hydrophobic phospholipid prosthetic group that anchors proteins to...
    21 KB (2,595 words) - 15:26, 27 May 2024
  • Thumbnail for Alpha-tocopherol transfer protein
    Alpha-tocopherol transfer protein (α-TTP) is a protein that in humans is encoded by the TTPA gene. Familial isolated vitamin E deficiency GRCh38: Ensembl...
    7 KB (909 words) - 18:36, 28 December 2023
  • Thumbnail for Protein structure
    "hetero-", for example, a heterotetramer, such as the two alpha and two beta chains of hemoglobin. Proteins are frequently described as consisting of several...
    36 KB (4,022 words) - 18:30, 19 February 2024
  • Thumbnail for MTOR
    mTOR is a member of the phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR links with other proteins and serves as a core component...
    119 KB (12,654 words) - 16:07, 28 May 2024
  • Thumbnail for Protein kinase B
    domain of the Akt proteins, it binds either PIP3 (phosphatidylinositol (3,4,5)-trisphosphate, PtdIns(3,4,5)P3) or PIP2 (phosphatidylinositol (3,4)-bisphosphate...
    34 KB (3,754 words) - 20:14, 23 April 2024
  • Phosphatidylinositol 3-kinase-related kinases (PIKKs) are a family of Ser/Thr-protein kinases with sequence similarity to phosphatidylinositol-3 kinases...
    2 KB (106 words) - 09:29, 23 October 2022
  • Thumbnail for Kinase
    protein kinase Cell signaling Cyclin-dependent kinase G protein-coupled receptor Nucleoside-diphosphate kinase Phosphatase Phosphatidylinositol phosphate...
    33 KB (3,805 words) - 11:22, 1 April 2024
  • Thumbnail for Eukaryotic translation elongation factor 1 alpha 1
    Elongation factor 1-alpha 1 (eEF1a1) is a translation elongation protein, expressed across eukaryotes. In humans, it is encoded by the EEF1A1 gene. This...
    22 KB (2,672 words) - 20:37, 3 December 2023
  • Thumbnail for PI4KA
    Phosphatidylinositol 4-kinase alpha is an enzyme that in humans is encoded by the PI4KA gene. This gene encodes a 1-phosphatidylinositol 4-kinase which...
    9 KB (1,139 words) - 05:23, 29 November 2023
  • sufficient to reverse cell chirality through phosphatidylinositol 3-kinase/AKT signaling and alters junctional protein organization between cells with opposite...
    27 KB (2,650 words) - 21:16, 19 March 2024
  • Thumbnail for Cell membrane
    contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach...
    59 KB (6,906 words) - 21:19, 12 April 2024
  • Thumbnail for Casein kinase 1, alpha 1
    associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins". The Journal of Biological Chemistry...
    3 KB (340 words) - 01:58, 2 June 2024
  • Thumbnail for Chromosome 1
    5 PIAS3 (1q21) PI4KB: Phosphatidylinositol 4-kinase beta PIP5K1A (1q21): Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha PLA2G4A (1q31) PPOX: protoporphyrinogen...
    46 KB (3,284 words) - 04:21, 11 April 2024
  • for catalysing the transfer of a phosphate group from a nucleoside triphosphate donor, such as ATP, to tyrosine residues in proteins. Non-receptor tyrosine...
    21 KB (2,716 words) - 15:11, 26 August 2023
  • Thumbnail for CRAL-TRIO domain
    CRAL-TRIO domain (category Protein domains)
    the family are alpha-tocopherol transfer protein and phosphatidylinositol-transfer protein (Sec14). They transport their substrates (alpha-tocopherol and...
    4 KB (373 words) - 22:06, 22 August 2021
  • Thumbnail for PI4K2A
    Phosphatidylinositol 4-kinase 2-alpha is an enzyme that in humans is encoded by the PI4K2A gene. This gene encodes a phosphatidylinositol 4-kinase which...
    13 KB (1,482 words) - 20:42, 6 January 2024
  • Thumbnail for PI4KB
    4-kinase alpha (PI4KA) phosphatidylinositol 4-kinase beta (PI4KB) phosphatidylinositol 4-kinase 2-alpha (PI4K2A) phosphatidylinositol 4-kinase 2-beta (PI4K2B)...
    11 KB (1,334 words) - 20:40, 3 March 2023
  • Thumbnail for Phosphoinositide-dependent kinase-1
    protein kinase 1. PDPK1 functions downstream of PI3K through PDPK1's interaction with membrane phospholipids including phosphatidylinositols, phosphatidylinositol...
    18 KB (2,127 words) - 19:11, 8 April 2024
  • Thumbnail for PLCB2
    1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene. The gene codes for the enzyme...
    9 KB (1,039 words) - 07:56, 4 January 2024
  • PITPNM3 (category Proteins)
    Nir1 or membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3) is a mammalian protein that localizes to endoplasmic reticulum (ER) and plasma...
    10 KB (1,094 words) - 15:52, 4 December 2023
  • Thumbnail for Catenin beta-1
    β-catenin destabilization via a G-protein-dependent pathway, wherein activated Phospholipase Cβ hydrolyzes phosphatidylinositol-(4,5)-bisphosphate to diacylglycerol...
    107 KB (12,347 words) - 03:32, 27 May 2024
  • ends of the transmembrane domains promotes activation of the G protein-coupled alpha-factor receptor". Molecular and Cellular Biology. 24 (5): 2041–51...
    62 KB (6,781 words) - 07:35, 24 May 2024
  • enzymology, a phosphatidylinositol alpha-mannosyltransferase (EC 2.4.1.57) is an enzyme that catalyzes the chemical reaction in which at least one alpha-D-mannose...
    2 KB (139 words) - 18:17, 23 January 2024
  • Thumbnail for AKT1
    AKT1 (category Protein kinases)
    RAC(Rho family)-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily...
    24 KB (2,850 words) - 04:05, 29 September 2022