Physiologically based pharmacokinetic (PBPK) modeling is a mathematical modeling technique for predicting the absorption, distribution, metabolism and...
27 KB (3,156 words) - 00:35, 7 March 2025
Bioequivalence Generic drugs Physiologically based pharmacokinetic modelling Plateau principle Toxicokinetics Pharmacokinetics. (2006). In Mosby's Dictionary...
41 KB (4,312 words) - 18:59, 9 April 2025
Neuroinformatics Mathematical model Compartmental models in epidemiology Physiologically-based pharmacokinetic modelling Ermentrout, Bard; Terman H. David...
22 KB (3,104 words) - 15:21, 9 January 2025
able to quickly develop and easily maintain physiologically based pharmacokinetic modelling (PBPK) models. However, the syntax was defined with enough...
7 KB (999 words) - 11:05, 30 March 2025
engineering Biological neuron models Compartmental models in epidemiology Physiologically-based pharmacokinetic modelling Cobelli, Claudio; Foster, David...
12 KB (2,181 words) - 09:07, 8 November 2024
Nephrotoxicity Neurotoxicity Ototoxicity Paracelsus Physiologically-based pharmacokinetic modelling. Poison Reference dose Registry of Toxic Effects of...
27 KB (3,121 words) - 20:30, 17 April 2025
Biological half-life (category Pharmacokinetics)
and each part with a different biological half-life (physiologically-based pharmacokinetic modelling). Attempts to remove a substance from the whole organism...
23 KB (2,515 words) - 19:43, 4 November 2024
Pharmacometrics (category Pharmacokinetics)
Physiologically-Based Pharmacokinetic models integrate physiological information to simulate drug behavior in various tissues and organs. These models consider organ-specific...
10 KB (1,322 words) - 13:01, 10 March 2025
Chae YJ, Chung SJ, et al. (May 2021). "Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans". Pharmaceutics...
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Fluorodeoxyglucose Multi-compartment model Patlak plot Pharmacokinetics Physiologically-based pharmacokinetic modelling G. Lucignani; G. Paganelli; E. Bombardieri...
11 KB (1,610 words) - 16:11, 30 January 2025
Glycyrrhizin (section Pharmacokinetics)
DeJongh J (May 2001). "The pharmacokinetics of glycyrrhizic acid evaluated by physiologically based pharmacokinetic modeling". Drug Metabolism Reviews...
8 KB (580 words) - 12:36, 20 November 2024
Spendiff, M. K.; Cocker, J.; Loizou, G. D. (2006). "Physiologically based pharmacokinetic modelling of human exposure to 2-butoxyethanol". Toxicol. Lett...
26 KB (2,541 words) - 13:00, 13 April 2025
Drug discovery (redirect from Target base drug discovery)
metabolism Fragment-based drug discovery High content screening Pharmacogenetics Pharmacognosy Physiologically-based pharmacokinetic modelling Pre-clinical development...
58 KB (6,777 words) - 19:12, 24 January 2025
E, Park JS, et al. (14 March 2023). "Physiologically Based Pharmacokinetic Modelling to Predict Pharmacokinetics of Enavogliflozin, a Sodium-Dependent...
45 KB (4,644 words) - 02:01, 13 May 2025
First pass effect (category Pharmacokinetics)
metabolism because it is biochemically selective.[ambiguous] Physiologically based pharmacokinetic models (PBPK) are used to predict first-pass metabolism, although...
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ethylene glycol ethyl ether acetate and validation of a physiologically based pharmacokinetic model for rat and human". Toxicology and Applied Pharmacology...
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Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across Human Lifetime". Environmental Research...
9 KB (863 words) - 06:59, 6 January 2025
1515/jip-2012-0081. Collins Licata, A.; et al. (2001). "A Physiologically Based Pharmacokinetic Model for Methyl tert-Butyl Ether in Humans: Implementing Sensitivity...
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Leon Aarons (section Data modelling)
collaborated on earlier research published in 2008 used physiologically based pharmacokinetic modelling (PBPK) to "evaluate the potential CYP3A4 inhibitory...
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process parameters can then be integrated into so called "physiologically based pharmacokinetic models" or PBPK. In vitro studies permit a species-specific...
29 KB (3,125 words) - 16:15, 8 May 2025
2,4-Dinitrophenol (section Pharmacokinetics)
Dhaval K. (1 June 2022). "Physiologically-based pharmacokinetic model for 2,4-dinitrophenol". Journal of Pharmacokinetics and Pharmacodynamics. 49 (3):...
36 KB (3,735 words) - 05:53, 8 March 2025
Daridorexant (section Pharmacokinetics)
strong CYP3A4 inhibitor itraconazole, on the basis of physiologically-based pharmacokinetic modeling, would be expected to increase daridorexant exposure...
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Underlying the Pharmacokinetic Goldenseal-Midazolam Interaction: Application of In Vitro Assays and Physiologically Based Pharmacokinetic Models to Understand...
81 KB (7,834 words) - 19:44, 15 April 2025
Valganciclovir (section Pharmacokinetics)
M, Greig G, Reigner B, Parrott N (November 2016). "A Physiologically Based Pharmacokinetic Model for Ganciclovir and Its Prodrug Valganciclovir in Adults...
16 KB (1,240 words) - 15:32, 12 January 2025
Cheminformatics Biomedical informatics Orphan drug Physiologically-based pharmacokinetic modelling Pharmaceuticals in India Generic drug New chemical...
90 KB (12,116 words) - 16:31, 10 May 2025
S, Shipp AM, Yager JW, Clewell HJ (January 2004). "Physiologically based pharmacokinetic modeling of arsenic in the mouse". Journal of Toxicology and...
82 KB (9,616 words) - 02:24, 6 May 2025
Series. 66: 41. Luu HM, Hutter JC, Bushar HF (1998). "A Physiologically Based Pharmacokinetic Model for 2,4-toluenediamine Leached from Polyurethane foam-covered...
123 KB (14,367 words) - 11:06, 3 May 2025
Series. 66: 41. Luu HM, Hutter JC, Bushar HF (1998). "A Physiologically based Pharmacokinetic Model for 2,4-toluenediamine Leached from Polyurethane foam-covered...
117 KB (13,118 words) - 23:21, 30 April 2025
active metabolite. El-Masri HA, Portier CJ (June 1998). "Physiologically based pharmacokinetics model of primidone and its metabolites phenobarbital and...
2 KB (62 words) - 01:52, 25 February 2021
Suk-Jae; Lee, Kyeong-Ryoon (2021-05-29). "Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans". Pharmaceutics...
43 KB (4,990 words) - 22:23, 18 April 2025