POU class 1 homeobox 1, also known as pituitary-specific positive transcription factor 1 (PIT1), POU domain, class 1, transcription factor 1 (POU1F1) and...
11 KB (1,372 words) - 18:38, 30 January 2024
Bolshoy Pit, a tributary of the Yenisei, Russia Pituitary-specific positive transcription factor 1 (PIT-1), a gene The Pit (disambiguation) Pitt (disambiguation)...
4 KB (618 words) - 23:26, 8 April 2025
Growth hormone–releasing hormone (redirect from Growth hormone-releasing factor)
"Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295...
12 KB (1,281 words) - 15:01, 22 July 2024
Paracrine signaling (redirect from Paracrine factor)
nucleus, where they act as transcription factors and either up-regulate or down-regulate in the expression of a target gene. Specific TGF-β ligands will result...
45 KB (4,879 words) - 07:05, 7 April 2025
The steroidogenic factor 1 (SF-1) protein is a transcription factor involved in sex determination by controlling the activity of genes related to the...
29 KB (3,478 words) - 23:06, 27 March 2024
PITX1 (category Transcription factors)
dominant clubfoot. PITX1 has been shown to interact with pituitary-specific positive transcription factor 1. GRCh38: Ensembl release 89: ENSG00000069011 – Ensembl...
11 KB (1,277 words) - 10:04, 9 March 2025
Luteinizing hormone (category Hormones of the hypothalamus-pituitary-gonad axis)
stimulating the release of LH from the anterior pituitary. Some studies, however, attribute the LH surge to positive feedback from estradiol after production...
36 KB (3,608 words) - 15:42, 17 February 2025
Growth hormone 1, also known as pituitary growth hormone or simply as growth hormone (GH) somatotropin, is a protein that in humans is encoded by the GH1...
3 KB (404 words) - 17:33, 11 November 2023
c-Jun. The activated transcription factor c-Jun regulates nuclear transcription via AP-1 to increase pro-apoptotic gene transcription. There is evidence...
27 KB (3,110 words) - 09:14, 8 March 2025
Gonadotropic cell (redirect from Pituitary gonadotrope cell)
cell-to-cell interactions, signaling pathways, and numerous transcription factors. Of the pituitary endocrine cells, the gonadotropic cells are the last to...
15 KB (1,684 words) - 17:36, 5 December 2024
embryonic factor". Drolet DW, Scully KM, Simmons DM, et al. (1991). "TEF, a transcription factor expressed specifically in the anterior pituitary during...
6 KB (748 words) - 02:35, 29 November 2023
NANOG and GATA4 (transcription factors essential for proper cell differentiation and embryonic development), indicating a specific role of FGF2 in PE...
22 KB (2,698 words) - 17:05, 16 July 2024
PITX2 (category Transcription factors)
Paired-like homeodomain transcription factor 2 also known as pituitary homeobox 2 is a protein that in humans is encoded by the PITX2 gene. This gene encodes...
27 KB (3,434 words) - 05:36, 5 February 2025
LHX3 (category Transcription factors)
cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Two transcript...
10 KB (1,092 words) - 07:32, 5 February 2025
Prolactin (category Anterior pituitary hormones)
anterior pituitary, decidua, myometrium, breast, lymphocytes, leukocytes and prostate. Pituitary prolactin is controlled by the Pit-1 transcription factor, which...
57 KB (6,049 words) - 12:09, 4 May 2025
the NKX2-1 gene. Thyroid transcription factor-1 (TTF-1) is a protein that regulates transcription of genes specific for the thyroid, lung, and diencephalon...
19 KB (2,118 words) - 19:06, 28 August 2023
IRF3 (redirect from Interferon regulatory factor-3)
regulatory factor 3, also known as IRF3, is an interferon regulatory factor. IRF3 is a member of the interferon regulatory transcription factor (IRF) family...
12 KB (1,493 words) - 01:36, 11 December 2023
the secretion of gastric acid. Ghrelin activates cells in the anterior pituitary gland and hypothalamic arcuate nucleus, including neuropeptide Y neurons...
44 KB (4,802 words) - 17:42, 20 March 2025
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role...
34 KB (4,512 words) - 06:26, 2 May 2025
from the names of three transcription factors: the Pituitary-specific Pit-1 the Octamer transcription factor proteins Oct-1 and Oct-2 (octamer sequence...
9 KB (999 words) - 14:46, 22 March 2023
of a Cre regulatory component, suggesting a putative role for the transcription factor CREB and the source of BDNF's activity-dependent effects . There...
50 KB (5,881 words) - 13:31, 5 May 2025
Breast development (section Growth factors)
Growth hormone (GH), which is secreted from the pituitary gland, and insulin-like growth factor 1 (IGF-1), which is produced in the body in response to...
59 KB (6,495 words) - 19:10, 25 November 2024
positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT)...
60 KB (6,879 words) - 01:06, 1 March 2025
growth genes. ETS1 activates MET transcription in vitro. MET transcription is activated by hypoxia-inducible factor 1 (HIF1), which is activated by low...
59 KB (6,731 words) - 19:27, 17 March 2025
Amphetamine (redirect from 1-Phenyl-2-Aminopropane)
continuous stimulant therapy is 2 cm. Transcription factors are proteins that increase or decrease the expression of specific genes. In simpler terms, this necessary...
306 KB (32,344 words) - 13:24, 14 May 2025
been found to inhibit BDNF transcription. In the hypothalamic-pituitary-adrenal axis (HPA axis), corticotropin-releasing factor (CRF) is secreted by the...
35 KB (4,421 words) - 01:52, 22 November 2024
POU transcription factors Pit1 (Pituitary-specific positive transcription factor 1, Pou1f1), Oct1 (Pou2f1), and the Caenorhabditis elegans factor Unc86...
17 KB (2,159 words) - 03:13, 3 December 2023
Vasoactive intestinal peptide (category Hormones of the hypothalamic-pituitary-prolactin axis)
signaling pathways like the phosphorylation of CREB and other transcriptional factors. The mPer1 and mPer2 promoters have CRE domains and thus provides...
23 KB (2,720 words) - 21:13, 18 May 2024
amino acid residues. POMC is synthesized in corticotrophs of the anterior pituitary from the 267-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin...
20 KB (2,226 words) - 20:43, 22 March 2025
LHX4 (category Transcription factors)
protein may function as a transcriptional regulator and be involved in control of differentiation and development of the pituitary gland. Mutations in this...
5 KB (549 words) - 23:09, 2 January 2025