The potassium channel RNA editing signal is an RNA element found in human Kv1.1 and its homologues which directs the efficient modification of an adenosine...

adenosines within double-stranded regions of pre-mRNAs (e.g. Potassium channel RNA editing signal) and deaminate them to inosine. Inosines are recognised...

factor by selectively suppressing dsRNA-dependent and antiviral pathways. RNA editing Potassium channel RNA editing signal ADARB1 Z-DNA GRCh38: Ensembl release...

PGK RNA motif Potassium channel RNA editing signal Potato virus X cis-acting regulatory element PotC RNA motif Poxvirus AX element late mRNA cis-regulatory...

with the editing region is known as an Editing Complementary Sequence (ECS) The pre-mRNA of this subunit is edited at one position. The R/G editing site is...

Kv7.1 (KvLQT1) is a potassium channel protein whose primary subunit in humans is encoded by the KCNQ1 gene. Its mutation causes Long QT syndrome, Kv7...

undergoes pre-mRNA editing by the ADAR family of enzymes. A-to-I editing changes an isoleucine codon to code for a methionine residue. This editing is thought...

composition of that mRNA. An example in humans is the apolipoprotein B mRNA, which is edited in some tissues, but not others. The editing creates an early...

undergoes RNA editing. The type of RNA editing that occurs in the pre-mRNA of GluR-2 is adenosine-to-inosine (A-to-I) editing. A-to-I RNA editing is catalyzed...

M, Reenan R (October 2004). "Control of human potassium channel inactivation by editing of a small mRNA hairpin". Nat. Struct. Mol. Biol. 11 (10): 950–6...

back out of the plasma membrane. Potassium channels are then activated, and there is an outward current of potassium ions, returning the electrochemical...

the mRNA. miRNAs resemble the small interfering RNAs (siRNAs) of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts...

The renal outer medullary potassium channel (ROMK) is an ATP-dependent potassium channel (Kir1.1) that transports potassium out of cells. It plays an...

for a protein known as Kv11.1, the alpha subunit of a potassium ion channel. This ion channel (sometimes simply denoted as 'hERG') is best known for...

lipid-gated ion channel belonging to the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two...

Potassium voltage-gated channel subfamily A member 2 also known as Kv1.2 is a protein that in humans is encoded by the KCNA2 gene. Potassium channels...

ion channels and signaling cascades. Interactions with TREK1 potassium channels are a prime example of this relationship. TREK1 is a two-pore channel that...

subunits to create different isoforms to give channels different properties due to palmitoylation and RNA editing. Other forms of modulation on the β subunit...

Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene. It contributes to the...

channel impermeable to calcium. This is determined by post-transcriptional modification — RNA editing — of the Q-to-R editing site of the GluA2 mRNA....

permeability to Ca2+ is usually very slight but varies with subunits and RNA editing at the tip of the p loop. Many kainate receptors appear to exist as heteromers...

periodic paralysis, paramyotonia congenita, and potassium-aggravated myotonia. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed...

transcribed into mRNA and translated into preproinsulin. After translation, the preproinsulin precursor contains an N-terminal signal peptide that allows...

voltage-gated channel alpha subunit 9 plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by...

post-synaptic scaffolds and ion channels that generate fast electrical signals. The ability to generate electric signals was a key innovation in the evolution...

Potassium voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5...

Potassium channel subfamily K member 9 is a protein that in humans is encoded by the KCNK9 gene. This gene encodes K2P9.1, one of the members of the superfamily...

outer medullar potassium 1 (ROMK1) and large conductance calcium-activated potassium channel (BKCa) are the two primary channels for potassium secretion....

family. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites...

complete gap junction channel. The connexin-43 internal ribosome entry site is an RNA element present in the 5' UTR of the mRNA of GJA1. This internal...