A Pro-arrhythmic agent is a chemical, drug, or food that promotes cardiac arrhythmias. Omega 3 fatty acids. Chocolate, Coffee, Tea Caffeine, cocaine,...
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myocyte repolarization. Class III agents have the potential to prolong the QT interval of the EKG, and may be proarrhythmic (more associated with development...
21 KB (1,997 words) - 21:23, 15 July 2025
places. Last, the electrophysiologist may administer various drugs (proarrhythmic agents) to induce arrhythmia (inducibility of VT/VF). If the arrhythmia...
11 KB (1,460 words) - 05:22, 5 February 2025
Encainide (category Antiarrhythmic agents)
name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects. Iferanserin Cardiac Arrhythmia...
3 KB (113 words) - 16:37, 23 September 2024
Quinidine (category Antiarrhythmic agents)
atrial fibrillation after patients undergo cardioversion, but it has proarrhythmic effects and trials suggest that it may lead to an overall increased...
19 KB (1,911 words) - 13:49, 9 June 2025
JJC8-088 (category Pro-motivational agents)
hERG Activation by Its Blocker: A Mechanism to Reduce Drug-Induced Proarrhythmic Risk. Int. J. Mol. Sci. 2023; 24(22): 16261. doi:10.3390/ijms242216261...
8 KB (719 words) - 14:24, 8 June 2025
Cardiac Arrhythmia Suppression Trial (category Antiarrhythmic agents)
excess mortality was attributed to proarrhythmic effects of the agents. Class I antiarrhythmics are proarrhythmic during heart ischemia in animals. Cardiac...
5 KB (550 words) - 18:31, 24 February 2025
HBI-3000 (category Antiarrhythmic agents)
agent. The administration of HBI-3000 to isolated heart muscle cells demonstrated the potential to improve arrhythmias while having low proarrhythmic...
7 KB (629 words) - 19:03, 27 February 2024
used. However, the options for antiarrhythmic agents are limited because certain agents can be proarrhythmic in the setting of myocardial dysfunction in...
16 KB (1,745 words) - 13:03, 15 March 2025
istaroxime may permit cytosolic calcium accumulation while avoiding a proarrhythmic state. Proposed mechanisms for istaroxime's antiarrhythmic effect include...
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Lorcainide (category Antiarrhythmic agents)
however, they often have a narrow therapeutic index and can also be proarrhythmic. Wolff–Parkinson–White syndrome (WPW) is a pre-excitation syndrome in...
11 KB (996 words) - 08:18, 9 September 2024
Chattipakorn SC, Chattipakorn N (January 2020). "Doxorubicin and its proarrhythmic effects: A comprehensive review of the evidence from experimental and...
85 KB (9,593 words) - 13:30, 22 May 2025
Dependence of Antiarrhythmic Agents: Pro- and Antiarrhythmic Actions", Antiarrhythmic Drugs: Mechanisms of Antiarrhythmic and Proarrhythmic Actions, Springer Berlin...
30 KB (2,842 words) - 21:56, 29 May 2025
Channel-blocking Profile of the Novel Combined Ion Channel Blocker AZD1305 and Its Proarrhythmic Potential Versus Dofetilide in the Methoxamine-sensitized Rabbit in...
8 KB (785 words) - 12:23, 6 June 2025
according to periodical ligand binding: implications for antiarrhythmic and proarrhythmic efficacy". Journal of Cardiovascular Pharmacology. 15 (6): 998–1009...
8 KB (827 words) - 03:19, 27 August 2023
the simulations, several aspects can be investigated to identify the proarrhythmicity of a new pharmacological compound. The typical changes, known as repolarization...
31 KB (3,410 words) - 18:27, 12 June 2025
Omega-3 Polyunsaturated Fatty Acids on Cardiac Rhythm: Antiarrhythmic, Proarrhythmic, Both or Neither? (editor). Frontiers. 2013. ISBN 978-2889190881. Billman...
28 KB (3,230 words) - 16:24, 31 May 2025