• Thumbnail for Prolactin
    autocrine, and paracrine manners through the prolactin receptor and numerous cytokine receptors. Pituitary prolactin secretion is regulated by endocrine neurons...
    58 KB (6,049 words) - 23:34, 22 May 2025
  • The prolactin receptor (PRLR) is a type I cytokine receptor encoded in humans by the PRLR gene on chromosome 5p13-14. It is the receptor for prolactin (PRL)...
    17 KB (1,865 words) - 06:48, 21 December 2023
  • Thumbnail for Prolactin modulator
    respectively. Prolactin inhibitors are mainly used to treat hyperprolactinemia (high prolactin levels). Agonists of the dopamine D2 receptor such as bromocriptine...
    7 KB (573 words) - 21:50, 24 November 2024
  • Thumbnail for Hyperprolactinaemia
    condition characterized by abnormally high levels of prolactin in the blood. In women, normal prolactin levels average to about 13 ng/mL, while in men, they...
    53 KB (5,758 words) - 23:33, 22 May 2025
  • Thumbnail for Human placental lactogen
    agonist of the prolactin receptor and a weak agonist of the growth hormone receptor. hPL has been found to bind to the prolactin receptor with equal affinity...
    9 KB (1,002 words) - 04:41, 19 April 2025
  • Thumbnail for Prolactin-releasing peptide
    release and regulates the expression of prolactin through binding to the prolactin-releasing peptide receptor (GPR10). PrRP has 20 amino acids, and is...
    5 KB (624 words) - 22:03, 22 November 2023
  • Thumbnail for Prolactin-releasing peptide receptor
    The prolactin-releasing peptide receptor (PrRPR) also known as G-protein coupled receptor 10 (GPR10) is a protein that in humans is encoded by the PRLHR...
    8 KB (986 words) - 02:51, 10 March 2024
  • Thumbnail for Galactagogue
    system in such a way to increase the production of prolactin; specifically, by blocking the D2 receptor. There is some evidence to suggest that mothers who...
    12 KB (1,150 words) - 04:13, 3 February 2025
  • Thumbnail for Cabergoline
    Cabergoline (category Prolactin inhibitors)
    among others, is a dopaminergic medication used in the treatment of high prolactin levels, prolactinomas, Parkinson's disease, and for other indications...
    35 KB (3,056 words) - 20:13, 29 May 2025
  • Thumbnail for Erythropoietin receptor
    pathways activated by the EpoR are common to many other receptors; replacing EpoR with prolactin receptor supports erythroid survival and differentiation in...
    29 KB (3,348 words) - 06:59, 2 June 2025
  • A (2004). "Endogenous human prolactin and not exogenous human prolactin induces estrogen receptor α and prolactin receptor expression and increases estrogen...
    59 KB (6,495 words) - 19:13, 23 May 2025
  • Thumbnail for Lisuride
    Lisuride (category Prolactin inhibitors)
    Parkinson's disease and ability to suppress prolactin levels, while interactions with serotonin receptors are thought to be principally involved in its...
    45 KB (3,822 words) - 00:47, 10 May 2025
  • Thumbnail for Domperidone
    Domperidone (category Prolactin releasers)
    like gastroparesis (delayed gastric emptying). It raises the level of prolactin in the human body and is used off label to induce and promote breast milk...
    64 KB (5,751 words) - 20:37, 29 May 2025
  • Thumbnail for Hypoprolactinemia
    deficiency in the serum levels of the hypothalamic-pituitary hormone prolactin. Hypoprolactinemia is associated with ovarian dysfunction in women, and...
    7 KB (639 words) - 10:00, 11 June 2024
  • Thumbnail for Growth hormone
    functional interaction with the GH receptor. It appears that, in structure, GH is evolutionarily homologous to prolactin and chorionic somatomammotropin...
    58 KB (6,716 words) - 21:00, 29 May 2025
  • Erythropoietin receptor GM-CSF receptor G-CSF receptor Thrombopoietin receptor Growth hormone receptor Prolactin receptor Leptin receptor Oncostatin M receptor Leukemia...
    5 KB (514 words) - 21:40, 3 October 2024
  • Thumbnail for 5-HT receptor
    hormones, including oxytocin, prolactin, vasopressin, cortisol, corticotropin, and substance P, among others. Serotonin receptors influence various biological...
    65 KB (5,273 words) - 08:55, 28 May 2025
  • Thumbnail for Dopamine receptor D2
    D2–ghrelin receptor D2sh–TAAR1 The D2 receptor has been shown to form heterodimers in vitro (and possibly in vivo) with DRD3, DRD5, and 5-HT2A. Prolactin modulator...
    35 KB (3,963 words) - 03:03, 2 June 2025
  • Thumbnail for Lactation
    S2CID 37973363. Khong HK, Kuah MK, Jaya-Ram A, Shu-Chien AC (May 2009). "Prolactin receptor mRNA is upregulated in discus fish (Symphysodon aequifasciata) skin...
    36 KB (4,247 words) - 12:23, 24 May 2025
  • Thumbnail for Silybum marianum
    v t e Galactagogues Prolactin receptor agonists Growth hormone/somatotropin Human placental lactogen Prolactin Prolactin releasers Others Breast development...
    16 KB (1,855 words) - 01:36, 3 May 2025
  • Hypothalamic–pituitary–prolactin axis Lin, S. H. (2008). "Prolactin-Releasing Peptide". Orphan G Protein-Coupled Receptors and Novel Neuropeptides....
    1 KB (181 words) - 14:07, 14 November 2022
  • ; Kim, M.; Zhuang, S.; Chin, Y. E. (2010). "Acetylation modulates prolactin receptor dimerization". Proceedings of the National Academy of Sciences. 107...
    62 KB (6,845 words) - 06:02, 23 May 2025
  • Thumbnail for Galega officinalis
    v t e Galactagogues Prolactin receptor agonists Growth hormone/somatotropin Human placental lactogen Prolactin Prolactin releasers Others Breast development...
    9 KB (845 words) - 04:18, 6 February 2025
  • Thumbnail for Dopamine
    supplies the pituitary gland. The prolactin cells that produce prolactin, in the absence of dopamine, secrete prolactin continuously; dopamine inhibits...
    140 KB (14,335 words) - 21:36, 31 May 2025
  • Thumbnail for Hypothalamic–pituitary–prolactin axis
    The hypothalamic–pituitary–prolactin axis (HPP axis), also known as the hypothalamic–pituitary–mammary axis or hypothalamic–pituitary–breast axis, is...
    3 KB (223 words) - 08:35, 5 December 2024
  • The orexin receptor (also referred to as the hypocretin receptor) is a G-protein-coupled receptor that binds the neuropeptide orexin. There are two variants...
    15 KB (1,368 words) - 14:59, 29 May 2025
  • Thumbnail for Diisobutyl phthalate
    cytokine-cytokine receptor pathway. There are two pathways affected: the tumour necrosis factor receptor superfamily (TNFRSF) and the prolactin receptor pathway...
    33 KB (3,409 words) - 21:54, 12 April 2025
  • Thumbnail for Risperidone
    Risperidone (category Prolactin releasers)
    breaks, all of which are associated with increased prolactin secretion. Alpha α1 adrenergic receptors: This action accounts for the orthostatic hypotensive...
    56 KB (5,131 words) - 22:05, 29 May 2025
  • Thumbnail for Metergoline
    Metergoline (category Prolactin inhibitors)
    the ergoline group which is used as a prolactin inhibitor in the treatment of hyperprolactinemia (high prolactin levels) and to suppress lactation. Metergoline...
    8 KB (431 words) - 20:49, 19 February 2025
  • Thumbnail for GABA receptor
    of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled...
    35 KB (3,892 words) - 18:09, 21 May 2025