The replication factor C, or RFC, is a five-subunit protein complex that is required for DNA replication. The subunits of this heteropentamer are named...

Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA replication of chromosomal DNA...

near perfect fidelity for DNA replication. In a cell, DNA replication begins at specific locations (origins of replication) in the genome which contains...

is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase...

clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. PCNA is a homotrimer and achieves...

modification for Sid Meier's Civilization IV Regenerative fuel cell Replication factor C, a protein complex Radio frequency choke, a type of choke Reconstruction...

Replication factor C subunit 4 is a protein that in humans is encoded by the RFC4 gene. The elongation of primed DNA templates by DNA polymerase delta...

Replication factor C subunit 5 is a protein that in humans is encoded by the RFC5 gene. The elongation of primed DNA templates by DNA polymerase delta...

The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. Propagation of the...

Replication factor C subunit 2 is a protein that in humans is encoded by the RFC2 gene. The elongation of primed DNA templates by DNA polymerase delta...

replication factor 1) is a protein that in humans is encoded by the CDT1 gene. It is a licensing factor that functions to limit DNA from replicating more...

Replication factor C subunit 3 is a protein that in humans is encoded by the RFC3 gene. The elongation of primed DNA templates by DNA polymerase delta...

(Sep 2002). "A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase". Molecular and Cellular Biology...

of CANVAS cases have been found to be caused by a mutation in the replication factor C subunit 1 gene. CANVAS is typically inherited in an autosomal recessive...

proliferating cell nuclear antigen (PCNA). As well, the multisubunit protein replication factor C, through its role as the clamp loader for PCNA (which involves catalysing...

presence of PCNA (proliferating cell nuclear antigen), RFC (replication factor C) and RPA (replication protein A). Either DNA polymerase epsilon or DNA polymerase...

The replication crisis, also known as the reproducibility or replicability crisis, is the growing number of published scientific results that other researchers...

theorem. Replication in computing can refer to: Data replication, where the same data is stored on multiple storage devices Computation replication, where...

amino acids. The eukaryotic equivalent to the DNA clamp loader is replication factor C, with the subunits RFC1, RFC2, RFC3, RFC4, and RFC5. The domain is...

helps reduce exposed single stranded DNA during the repair process. Replication factor C (RFC) loads the Proliferating Cell Nuclear Antigen (PCNA) onto the...

consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA...

This gene encodes a short protein that forms part of the Ctf18 replication factor C (RFC) complex that occurs in both yeast and mammals. The heteroheptameric...

Lindsey-Boltz LA, Sancar A (May 2002). "Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low...

never separate after replication. Another significant tie between DNA replication and cohesion pathways is through Replication Factor C (RFC). This complex...

within the four small subunits of human replication factor C required for complex formation and DNA replication". The Journal of Biological Chemistry....

replicon model for replication initiation. According to the replicon model, two components control replication initiation: the replicator and the initiator...

rate of DNA replication during S phase of the cell cycle is dependent on the processivity of the DNA polymerases performing the replication. DNA clamp...

is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon". Nucleic Acids Res...

domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells". The EMBO...

A pre-replication complex (pre-RC) is a protein complex that forms at the origin of replication during the initiation step of DNA replication. Formation...