Repulsive guidance molecules (RGMs) are members of a three gene family (in vertebrates) composed of RGMa, RGMb, and RGMc (also called hemojuvelin). RGMa...

Repulsive guidance molecule B (RGMb), also known as DRAGON (DRG11-responsive axonal guidance and outgrowth of neurite), is a bone morphogenetic protein...

Repulsive guidance molecule A (RGMa) is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family. Together with BMPR1A...

Hemojuvelin (HJV), also known as repulsive guidance molecule C (RGMc) or hemochromatosis type 2 protein (HFE2), is a membrane-bound and soluble protein...

fully human monoclonal antibody developed by AbbVie against repulsive guidance molecule A (RGMa). It has been tested in people with multiple sclerosis...

target is accomplished with relatively few guidance molecules. Growth cone receptors respond to the guidance cues. Growing axons have a highly motile structure...

PMC 7078468. PMID 32184239. Bell, Christian (2013). "Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub". Science. 341 (6141): 77–80. Bibcode:2013Sci...

2009). "Molecular biology, genetics and biochemistry of the repulsive guidance molecule family". The Biochemical Journal. 422 (3): 393–403. doi:10.1042/BJ20090978...

Guidance cues are essential for nervous system development as well as synaptic maintenance and remodeling. Guidance cues--attractive or repulsive--are...

are caused by mutations in the hemojuvelin gene (HJV or RGMc/repulsive guidance molecule c). The exceptions, people who have mutations in the gene for...

(IP-10) Crohn's disease, ulcerative colitis Elezanumab mab human repulsive guidance molecule A (RGMA) spinal cord injury and multiple sclerosis Elgemtumab...

through an internal change in the growth cone of the RGC, netrin-1 becomes repulsive, pushing the axon away from the optic disc. This is mediated through a...

the mechanisms that determine skeletal cell fusion via RGMa (repulsive guidance molecule a) binding. GRCh38: Ensembl release 89: ENSG00000067141 – Ensembl...

of repulsive guidance. Robo receptors were initially identified in Drosophila melanogaster using a forward genetic screen to search for molecules involved...

membrane which contains receptors, and cell adhesion molecules that are important for axon growth and guidance. In between filopodia—much like the webbing of...

formation of the (TEBs), suggesting that rather than acting as a guidance molecule as in neuronal systems, netrin 1 serves as an adhesive in mammary...

homologs of Down syndrome adhesion molecule. Like many neuronal receptors, Dscam proteins have multiple functions, with repulsive and attractive roles that are...

target area by a perimeter of cues repulsive to the growth cone. Axons express patterns of cell-surface adhesion molecules that allow them to match with specific...

109° predicted for a tetrahedral angle, and this can be explained by a repulsive interaction between the lone pairs. Various computational criteria for...

bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance". Cell. 96 (6): 795–806. doi:10.1016/S0092-8674(00)80590-5. PMID 10102268...

glycoprotein in the immunoglobulin (Ig) – related superfamily of cell adhesion molecules (CAMs). It was first identified in the developing grasshopper embryo,...

Ephrin-B2 is expressed at the chiasm midline by radial glia and acts as a repulsive signal to axons originating from the ventrotemporal retina expressing...

functions including axon guidance and angiogenesis. Slit refers to a secreted protein that is most widely known as a repulsive axon guidance cue, and Robo refers...

not your clients? And lasers, and all these supreme bacteria, all that repulsive filth, until the right moment hidden in safes? Strugatsky, Arkady and...

(October 2000). "Attractive and repulsive interactions between female and male gametophytes in Arabidopsis pollen tube guidance" (PDF). Development. 127 (20):...

Togari A, Mogi M, Arai M, et al. (2001). "Expression of mRNA for axon guidance molecules, such as semaphorin-III, netrins and neurotrophins, in human osteoblasts...

polarity required for axon guidance. Recent findings have shown that UNC-129 is also responsible for long range repulsive guidance of UNC-6. This mechanism...

There are several other molecules also involved in the guidance of axons to and across the midline. The slit proteins have repulsive functions, as opposed...

neuronal self-recognition is attained through families of cell recognition molecules which work as individual barcodes, allowing the discrimination of any...

polarity required for axon guidance. Recent findings have shown that UNC-129 is also responsible for long range repulsive guidance of UNC-6. This mechanism...