• Thumbnail for Syntaxin
    Syntaxins are a family of membrane integrated Q-SNARE proteins participating in exocytosis. Syntaxins possess a single C-terminal transmembrane domain...
    6 KB (702 words) - 13:56, 12 July 2025
  • Thumbnail for SNARE protein
    clasp releases closed syntaxin, remains associated with the N-terminal peptide of syntaxin (allowing association of the syntaxin SNARE domain with other...
    54 KB (6,597 words) - 21:12, 11 July 2025
  • Thumbnail for Syntaxin 3
    Syntaxin 3, also known as STX3, is a protein which in humans is encoded by the STX3 gene. The protein encoded by this gene is a member of the syntaxin...
    12 KB (1,462 words) - 04:49, 15 July 2025
  • Thumbnail for STXBP1
    Syntaxin-binding protein 1 (also known as Munc18-1) is a protein that in humans is encoded by the STXBP1 gene. This gene encodes a syntaxin-binding protein...
    20 KB (2,189 words) - 02:11, 18 January 2024
  • Thumbnail for STX1A
    STX1A (redirect from Syntaxin 1A)
    presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxin-1A is a member of the syntaxin superfamily. Syntaxins are nervous system-specific...
    26 KB (2,987 words) - 12:06, 13 January 2024
  • Thumbnail for STX6
    Syntaxin-6 is a protein that in humans is encoded by the STX6 gene. STX6 has been shown to interact with SNAP23, VAMP3 and VAMP4. The protein domain Syntaxin...
    12 KB (1,378 words) - 06:26, 24 December 2023
  • Thumbnail for STX2
    STX2 (redirect from Syntaxin-2)
    Syntaxin-2, also known as epimorphin, is a protein that in humans is encoded by the STX2 gene. The product of this gene belongs to the syntaxin/epimorphin...
    10 KB (1,272 words) - 04:48, 15 July 2025
  • Thumbnail for Syntaxin binding protein 2
    Syntaxin-binding protein 2 is a protein that in humans is encoded by the STXBP2 gene. GRCh38: Ensembl release 89: ENSG00000076944 – Ensembl, May 2017 GRCm38:...
    6 KB (748 words) - 01:41, 16 March 2024
  • Thumbnail for SNAP25
    family, and syntaxin-1 also help form the SNARE complex by each contributing a single α-helix. SNAP-25 assembles with synaptobrevin and syntaxin-1, and the...
    45 KB (5,006 words) - 08:04, 25 March 2024
  • Thumbnail for Syntaxin binding protein 3
    Syntaxin-binding protein 3 is a protein that in humans is encoded by the STXBP3 gene. Syntaxin binding protein 3 has been shown to interact with STX2 and...
    5 KB (571 words) - 14:21, 27 March 2022
  • exocytosis of neurons and neuroendocrine cells. Munc-18 binds syntaxin and forms a syntaxin/munc-18 complex which is thought to precede and/or regulate...
    7 KB (806 words) - 14:40, 12 April 2025
  • Thumbnail for Soluble NSF attachment protein
    Some of the first proteins identified as the receptors of SNAPs were syntaxin 1, SNAP-25 (synaptosome associated protein, 25kDa), and VAMP (synaptobrevin)...
    27 KB (3,333 words) - 21:10, 11 July 2025
  • intermediate complex composed of SNAP-25 and syntaxin-1, which later accommodates synaptobrevin-2 (the quoted syntaxin and synaptobrevin isotypes participate...
    15 KB (1,822 words) - 21:10, 2 May 2025
  • Thumbnail for STX8
    Syntaxin-8 is a protein that in humans is encoded by the STX8 gene. Syntaxin 8 directly interacts with HECTd3 and has similar subcellular localization...
    10 KB (1,289 words) - 03:02, 10 March 2025
  • Thumbnail for STXBP5
    Syntaxin-binding protein 5 is a protein that in humans is encoded by the STXBP5 gene. It is also known as tomosyn, after 友, "friend" in Japanese, for its...
    6 KB (708 words) - 09:35, 24 June 2025
  • Thumbnail for Hemophagocytic lymphohistiocytosis
    FHL2: PRF1 (Perforin) FHL3: UNC13D (Munc13-4) FHL4: STX11 (Syntaxin 11) FHL5: STXBP2 (Syntaxin binding protein 2)/UNC18-2 Nearly half of the cases of type...
    33 KB (3,699 words) - 01:08, 30 June 2025
  • Thumbnail for STX4
    Syntaxin-4 is a protein that in humans is encoded by the STX4 gene. STX4 has been shown to interact with: Gelsolin, NAPA, RAB4A, SNAP-25, SNAP23, STXBP1...
    17 KB (2,104 words) - 04:48, 15 July 2025
  • Thumbnail for Synaptic vesicle
    in this event. Munc13 is thought to stimulate the change of the t-SNARE syntaxin from a closed conformation to an open conformation, which stimulates the...
    34 KB (3,981 words) - 12:36, 24 May 2025
  • Thumbnail for Botulism
    serotype B, D, F and G cut synaptobrevin. Serotype C cleaves both SNAP-25 and syntaxin. This causes blockade of neurotransmitter acetylcholine release, ultimately...
    89 KB (9,619 words) - 01:33, 5 July 2025
  • Thumbnail for STX17
    Syntaxin 17 is a protein that in humans is encoded by the STX17 gene. In horses a duplication in intron 6 causes progressive graying. Syntaxin GRCh38:...
    3 KB (409 words) - 02:34, 28 March 2022
  • Thumbnail for STX10
    Syntaxin-10 (STX10) is a SNARE protein that is encoded by the STX10 gene. This protein is found in most vertebrates (including humans) but is noticeably...
    4 KB (538 words) - 11:19, 11 December 2023
  • Thumbnail for STX16
    Syntaxin-16 is a protein that in humans is encoded by the STX16 gene. It has been associated with pseudohypoparathyroidism type Ib. Losing this gene causes...
    5 KB (676 words) - 00:50, 15 October 2022
  • Thumbnail for STED microscopy
    independently of the SNARE motif's functionality, and binds to clustered syntaxin. Studies of complex organelles, like mitochondria, also benefit from STED...
    33 KB (3,867 words) - 20:11, 10 July 2025
  • Thumbnail for Exocytosis
    synaptotagmin and mediated by SNARE proteins. SNARE complex is formed by syntaxin-1 and SNAP25 at the presynaptic plasma membrane and Synaptrobrevin (VAMP)...
    19 KB (2,200 words) - 04:03, 9 June 2025
  • Thumbnail for Syntaphilin
    Syntaphilin is a protein that in humans is encoded by the SNPH gene. Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which...
    1 KB (175 words) - 04:43, 27 December 2023
  • Thumbnail for Thomas C. Südhof
    members of the SNARE complex: synaptobrevin, in the vesicular membrane, syntaxin, in the cell membrane, and SNAP25, which is tethered to the cytosolic side...
    21 KB (2,087 words) - 21:27, 10 June 2025
  • protein Maltose-binding protein Phosphatidylethanolamine binding protein 1 Syntaxin binding protein 3 Insulin-like growth factor-binding protein Methyl-CpG-binding...
    2 KB (263 words) - 21:49, 28 December 2020
  • Thumbnail for VAMP2
    protein that in humans is encoded by the VAMP2 gene. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components...
    17 KB (1,958 words) - 20:32, 9 January 2024
  • Thumbnail for NAPB
    PMID 11780052. Prekeris R, Klumperman J, Chen YA, Scheller RH (1998). "Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling...
    3 KB (397 words) - 04:15, 7 April 2022
  • Thumbnail for CPLX1
    proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the...
    6 KB (746 words) - 06:26, 17 March 2025