• Thumbnail for Transcription activator-like effector nuclease
    Transcription activator-like effector nucleases (TALEN) are restriction enzymes that can be engineered to cut specific sequences of DNA. They are made...
    27 KB (3,148 words) - 19:42, 31 October 2024
  • Thumbnail for Transcription activator-like effector
    TAL (transcription activator-like) effectors (often referred to as TALEs, but not to be confused with the three amino acid loop extension homeobox class...
    28 KB (2,796 words) - 03:03, 9 November 2023
  • Thumbnail for Effector (biology)
    these are the Transcription activator-like effector (TALE) proteins secreted by bacteria from the genus Xanthomonas. Fungal effectors are secreted by...
    11 KB (1,186 words) - 15:05, 4 February 2025
  • Thumbnail for Insert (molecular biology)
    run into expression issues in higher complex organisms. Transcription activator-like effector nuclease, TALENs, are a set of restriction enzymes that...
    11 KB (1,360 words) - 02:06, 3 December 2023
  • Thumbnail for Cas9
    different PAM sequences. Alongside zinc finger nucleases and transcription activator-like effector nuclease (TALEN) proteins, Cas9 is becoming a prominent...
    59 KB (7,257 words) - 05:11, 23 May 2025
  • Thumbnail for Artificial transcription factor
    size of the Cas protein hinders delivery into the cell. Transcription activator-like effectors (TALEs) are peptide structures composed of repeating 34...
    14 KB (1,698 words) - 06:42, 29 January 2023
  • Thumbnail for CRISPR gene editing
    CRISPR-based methods. In 2010, synthetic nucleases called transcription activator-like effector nucleases (TALENs) provided an easier way to target a double-stranded...
    176 KB (20,510 words) - 21:34, 22 May 2025
  • Thumbnail for Genome editing
    classes of these enzymes—zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and engineered meganucleases—were selected...
    79 KB (9,365 words) - 19:52, 22 May 2025
  • Examples of gene editing are CRISPR, zinc finger nuclease, transcription activator-like effector nuclease (TALEN), oligonucleotide directed mutagenesis +...
    2 KB (317 words) - 20:14, 28 May 2024
  • possible by prokaryotic genome manipulation is the use of transcription activator-like effector nucleases (TALENs) to target specific genes. TALENs are...
    13 KB (1,611 words) - 03:43, 8 April 2025
  • Thumbnail for Genetic engineering techniques
    accurate and easier systems to implement have been developed. Transcription activator-like effector nucleases (TALENs) and the Cas9-guideRNA system (adapted...
    55 KB (6,765 words) - 11:43, 11 December 2024
  • VP64-p65-Rta, or VPR, dCas9 activator was created by modifying an existing dCas9 activator, in which a Vp64 transcriptional activator is joined to the C terminus...
    22 KB (2,739 words) - 08:03, 1 April 2025
  • conditions. Two current means of gene editing are the use of transcription activator-like effector nucleases (TALENs) or clustered regularly interspaced short...
    15 KB (1,793 words) - 21:47, 27 April 2025
  • Thumbnail for Genetically modified food
    engineered nucleases: meganucleases, zinc finger nucleases, transcription activator-like effector nucleases (TALENs), and the Cas9-guideRNA system (adapted...
    145 KB (15,877 words) - 23:21, 22 May 2025
  • Thumbnail for Transcription factor
    promoting (as an activator), or blocking (as a repressor) the recruitment of RNA polymerase (the enzyme that performs the transcription of genetic information...
    75 KB (8,348 words) - 20:03, 18 March 2025
  • Thumbnail for Genetic engineering
    engineered nucleases: meganucleases, zinc finger nucleases, transcription activator-like effector nucleases (TALENs), and the Cas9-guideRNA system (adapted...
    135 KB (14,261 words) - 04:04, 30 April 2025
  • Thumbnail for Epigenome editing
    epigenetic processes to lead to targeted epigenetic editing. The Transcription Activator-Like Effector (TALE) protein recognizes specific DNA sequences based on...
    30 KB (3,420 words) - 09:03, 16 August 2024
  • Talen Talen, Rajgarh, village in Madhya Pradesh, India Transcription activator-like effector nuclease (TALEN) Talen Energy, an energy company Royal Talens...
    485 bytes (93 words) - 06:02, 26 January 2021
  • Thumbnail for Diatom
    "Inactivation of P haeodactylum tricornutum urease gene using transcription activator-like effector nuclease-based targeted mutagenesis". Plant Biotechnology...
    156 KB (16,262 words) - 20:12, 22 May 2025
  • Thumbnail for Insertion (genetics)
    separate class of mutations. Zinc finger nuclease(ZFN), Transcription activator-like effector nucleases (TALEN), and CRISPR gene editing are the three...
    8 KB (940 words) - 15:14, 8 February 2025
  • that destroy functionality of the gene.[citation needed] Transcription activator-like effector nucleases (TALENs) also contain a DNA binding domain and...
    22 KB (2,563 words) - 03:25, 8 April 2025
  • Thumbnail for Catabolite activator protein
    biology, catabolite activator protein (CAP), which is also known as cAMP receptor protein (CRP), is a trans-acting transcriptional activator in bacteria that...
    5 KB (637 words) - 10:07, 24 February 2025
  • regularly interspaced, short palindromic repeats (CRISPR)-Cas9, transcription activator-like effector nucleases (TALEN), meganucleases, and zinc finger nucleases...
    55 KB (7,122 words) - 04:03, 28 April 2025
  • Thumbnail for Type III secretion system
    Another well characterized class of T3SS effectors are Transcription Activator-like effectors (TAL effectors) from Xanthomonas. When injected into plants...
    46 KB (5,875 words) - 04:05, 24 March 2025
  • Thumbnail for Zinc finger
    Structural motif TAL effector Transcription Activator-Like Effector Nuclease Zinc finger inhibitor Zinc finger nuclease Zinc Finger Transcription Factor Klug A...
    42 KB (4,882 words) - 12:55, 7 February 2025
  • Thumbnail for DNA-binding protein
    DNA-binding protein (category Transcription factors)
    and this is the basis of zinc finger nucleases. Recently transcription activator-like effector nucleases (TALENs) have been created which are based on...
    22 KB (2,637 words) - 06:01, 3 April 2025
  • Thumbnail for Germline mutation
    specific to minimize off-target cleavage sites. The TALEN (transcription activator-like effector nucleases) genome editing system is used to induce a double-stranded...
    25 KB (3,085 words) - 03:46, 17 September 2024
  • Thumbnail for Xanthomonas oryzae pv. oryzae
    OsSWEET13 transcription promoter is related to resistance in an unusual way. Zhou et al., 2015 knocks out OsSWEET13 using PthXo2 – a transcription activator-like...
    15 KB (1,653 words) - 03:19, 22 December 2024
  • Thumbnail for Genetically modified organism
    engineered nucleases: meganucleases, zinc finger nucleases, transcription activator-like effector nucleases (TALENs), and the Cas9-guideRNA system (adapted...
    224 KB (24,732 words) - 19:18, 22 May 2025
  • HT-TALENS (HIV-targeted transcription activator-like effector nucleases) is an engineered plant protein that is a proposed cure for AIDS. The HIV genome...
    2 KB (247 words) - 00:37, 27 November 2023