• In cell biology, translational efficiency or translation efficiency is the rate of mRNA translation into proteins within cells. It has been measured in...
    2 KB (166 words) - 16:50, 12 February 2023
  • expressed genes towards the Pareto frontier for resource use and translational efficiency. Genes near the Pareto frontier were also shown to evolve more...
    37 KB (4,982 words) - 04:28, 6 May 2025
  • Thumbnail for Messenger RNA
    untranslated regions, including mRNA stability, mRNA localization, and translational efficiency. The ability of a UTR to perform these functions depends on the...
    51 KB (6,206 words) - 22:31, 29 May 2025
  • Thumbnail for K-mer
    coding and noncoding regions driven by some dinucelotides' reduced translational efficiency. Because there is not, it can therefore be inferred that the forces...
    50 KB (6,070 words) - 03:24, 5 May 2025
  • Translational lift is improved rotor efficiency resulting from directional flight in a helicopter. Translation is the conversion from the hover to forward...
    3 KB (387 words) - 20:12, 23 May 2024
  • one study. Secondary structures formed by the RBS can affect the translational efficiency of mRNA, generally inhibiting translation. These secondary structures...
    12 KB (1,334 words) - 23:00, 16 April 2025
  • mechanisms of its regulation. However, it has been shown that translational efficiency is reduced via diminished tRNA pools, which are required for the...
    11 KB (1,485 words) - 11:25, 11 February 2024
  • Thumbnail for Codon usage bias
    Because secondary structure of the 5’ end of mRNA influences translational efficiency, synonymous changes at this region on the mRNA can result in profound...
    28 KB (3,187 words) - 05:46, 20 May 2025
  • mutation found in the Kozak sequence and showed a 30% decrease in translational efficiency. It was found in a family from the Southeast Italy and they suffered...
    30 KB (3,674 words) - 01:19, 25 May 2025
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    differences in post-transcriptional regulation, mRNA stability, or translational efficiency. Another common limitation is the cellular burden that reporter...
    37 KB (3,974 words) - 15:18, 21 May 2025
  • Thumbnail for Uğur Şahin
    April 2010). "Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior...
    57 KB (6,166 words) - 17:19, 12 April 2025
  • Thumbnail for Three prime untranslated region
    in a tissue, the effects of localization, functional half-life, translational efficiency, and trans-acting elements must be determined to understand the...
    20 KB (2,555 words) - 11:24, 22 February 2024
  • Thumbnail for Evolution
    2011). "Explaining complex codon usage patterns with selection for translational efficiency, mutation bias, and genetic drift". PNAS. 108 (25): 10231–10236...
    240 KB (25,072 words) - 11:22, 29 May 2025
  • Thumbnail for Ambush hypothesis
    primates and though there are many factors that link molecular translational efficiency to the rate of morphogenesis, these findings suggests that not...
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  • Thumbnail for RNA editing
    primarily play a role in the structure of the rRNA in order to protect translational efficiency. Chemical modification in rRNA consists of methylation of ribose...
    61 KB (7,437 words) - 00:53, 7 March 2025
  • Thumbnail for Thermodynamic temperature
    that can occur in matter: that comprising the three translational degrees of freedom. The translational degrees of freedom are the familiar billiard ball-like...
    105 KB (13,825 words) - 05:37, 30 May 2025
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    (October 2013). "Structural and mechanistic basis for enhanced translational efficiency by 2-thiouridine at the tRNA anticodon wobble position". Journal...
    49 KB (5,299 words) - 16:59, 25 May 2025
  • has a notable effect on translational dynamics. There are various ways in which m6A is involved in translational efficiency. For instance, this modification...
    61 KB (7,733 words) - 15:59, 28 April 2025
  • and eukaryotes signal sequences may act co-translationally or post-translationally. The co-translational pathway is initiated when the signal peptide...
    15 KB (1,777 words) - 07:49, 20 May 2025
  • preferred in a gene, as a certain combination of codons may improve translational efficiency. A 2022 study reported that synonymous mutations in representative...
    22 KB (2,755 words) - 19:59, 1 February 2024
  • -3 and +4 of Kozak sequence have the most significant impact on translational efficiency. Hence, a sequence (A/G)NNAUGG is defined as a strong Kozak signal...
    28 KB (2,912 words) - 16:40, 9 October 2024
  • (August 2010). "Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior...
    83 KB (9,545 words) - 10:23, 30 March 2025
  • the 5’ UTR region of the TBX1 gene. This mutation increases TBX1 translational efficiency during key points in development, which is the functional equivalent...
    7 KB (874 words) - 01:29, 30 July 2023
  • Thumbnail for Hsp90 cis-regulatory element
    UTR of the Drosophila hsp90 mRNA. It is required for increased translational efficiency during the heat shock response. The hsp90 gene product is involved...
    2 KB (126 words) - 07:29, 28 February 2023
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    generation of force by any combination of pushing or pulling to modify the translational motion of an object, which is typically a rigid body (or an articulated...
    14 KB (1,767 words) - 12:11, 24 February 2025
  • Thumbnail for Interleukin 15
    alternative exon 5 containing another 3' splicing site, exhibited a high translational efficiency, and the product lack hydrophobic domains in the signal sequence...
    39 KB (4,458 words) - 06:59, 3 June 2024
  • oxidative shock. The mechanism by which OxyS interferes with rpoS mRNA translational efficiency is not known. However, the RNA-binding protein Hfq is implicated...
    18 KB (2,260 words) - 17:48, 26 May 2025
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    piglets at birth on rectal temperature over the first 24 h after birth1". Translational Animal Science. 4 (4): txaa183. doi:10.1093/tas/txaa183. PMC 7672461...
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  • Thumbnail for 2A peptides
    'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'". The Journal of General Virology...
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  • redox mechanism. Thiolation modification is believed to maintain translational efficiency and fidelity. MiaB and RimO are both well-characterized and bacterial...
    55 KB (6,104 words) - 18:20, 23 May 2025