cellular biology, the Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through...

cellular biology, paracrine signaling is a form of cell signaling, a type of cellular communication in which a cell produces a signal to induce changes in nearby...

de-regulated Wnt signaling pathway reduces proliferation and survival of cancer. These findings suggest that interference with Wnt signaling at the ligand-receptor...

The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred...

A biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions that occur within a biological cell when...

Reduction of canonical Wnt signals upon depletion of LRP5 and LRP6 results in p120-catenin degradation. The Wnt signaling pathway was first linked to bone...

WNT or Wnt may refer to: Windows NT WNT (Women's National Team) Wnt signaling pathway, a complex protein network The Weymouth New Testament (1902), translation...

The Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway, is a signaling pathway that controls organ size in animals through...

its function as a morphogen and signaling molecule. As a canonical Wnt ligand, WNT1 activates the Wnt/β-catenin pathway by binding to Frizzled and LRP5/LRP6...

The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different...

protein (SHH) is a major signaling molecule of embryonic development in humans and animals, encoded by the SHH gene. This signaling molecule is key in regulating...

collectively suggest a critical role of presenilin 1 in the Notch signaling pathway. Wnt signaling pathway has been shown to be involved in several critical steps...

cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous...

APC, WNT signaling pathway regulator is a protein that in humans is encoded by the APC gene. This gene encodes a tumor suppressor protein that acts as...

is a family of proteins involved in canonical and non-canonical Wnt signalling pathways. Dsh (Dvl in mammals) is a cytoplasmic phosphoprotein that acts...

mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling". Molecular and Cellular Biology. 23 (1): 131–9...

(1997). "The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation". Cell. 90 (1): 181–92....

signalling pathway PI3K/AKT/mTOR signalling pathway TGF beta signalling pathway TLR signalling pathway VEGF signalling pathway Wnt signalling pathway...

The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular...

attachment and signaling. The activity of one protein in particular, beta-catenin, is controlled by the APC protein (see: Wnt signaling pathway). Regulation...

also able to downregulate Wnt signaling by the formation of an inhibitory complex with the Frizzled receptors. The Wnt pathway plays a key role in embryonic...

protein-coupled receptors that serve as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled...

female to male sex reversal. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been...

Samumed's products in development target novel components of the Wnt signaling pathway. The company focuses on potential treatments for several diseases;...

rtPA-induced hemorrhagic transformation and activates the Wnt/β-catenin signaling pathway after acute ischemic stroke in rats". Molecular Neurobiology...

signal sensing) in a receptor give rise to a biochemical cascade, which is a chain of biochemical events known as a signaling pathway. When signaling...

result of genetic mutations in the Wnt signaling pathway that increases signaling activity. The Wnt signaling pathway normally plays an important role for...

involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer...

a SOX-like high mobility group domain. They are involved in the Wnt signaling pathway, particularly during embryonic and stem-cell development, but also...

Wnt signaling pathway, whose ligands are highly expressed in tumors. Recently, some of the upstream molecules present in this Wnt signaling pathway have...