Iron overload is the abnormal and increased accumulation of total iron in the body, leading to organ damage. The primary mechanism of organ damage is oxidative...

African iron overload is an iron overload disorder first observed among people of African descent in Southern Africa and Central Africa. It is now recognized...

understanding diseases of iron overload, such as hereditary hemochromatosis, and iron deficiency, such as iron-deficiency anemia. Iron is an essential bioelement...

primary storage area for iron and naturally accumulates excess iron over time, it is likely to be damaged by iron overload. Toxins may accumulate in...

secondary hemochromatosis due to iron overload from repeated transfusions. Patients with chronic iron overload can have iron deposits in their liver, heart...

total amount of iron stored in the body; hence, serum ferritin is used as a diagnostic test for iron-deficiency anemia and iron overload. Aggregated ferritin...

Nurchi, Valeria M.; Lachowicz, Joanna (2019). "Chapter 3. Iron Chelation for Iron Overload in Thalassemia". In Sigel, Astrid; Freisinger, Eva; Sigel,...

Hemosiderosis is a form of iron overload disorder resulting in the accumulation of hemosiderin. Types include: Transfusion hemosiderosis Idiopathic pulmonary...

transfusion in case of an anemia crisis. Complications of transfusion include iron overload with resulting heart or liver disease. Other symptoms of thalassemias...

deletion also had increased duodenal iron absorption, elevated plasma iron and transferrin saturation levels, and iron overload, mainly in hepatocytes. Mice have...

Other side effects, which may occur with excessive use, include iron overload and iron toxicity. Ferrous salts used as supplements by mouth include ferrous...

chemotherapy may develop iron deficiency and anemia, for which intravenous iron therapy is used to restore iron levels. Iron overload, which may occur from...

ineffective production of red blood cells, increased hemolysis, and iron overload. Diagnosis is by checking the medical history of near relatives, microscopic...

removes iron from the blood. This involves delivering iron chelating agents such as deferoxamine, deferiprone or deferasirox. If iron overload has caused...

and include anemia, pallor, tiredness, enlargement of the spleen, iron overload, abnormal bone structure, jaundice, and gallstones. In severe cases...

saturation is a common indicator of iron deficiency anemia whereas a high transferrin saturation may indicate iron overload or hemochromatosis. Transferrin...

Hemochromatosis type 4 is a hereditary iron overload disorder that affects ferroportin, an iron transport protein needed to export iron from cells into circulation...

dependence is iron overloading, which can damage the liver, heart, bone tissue and endocrine glands. Iron chelation therapy is used to treat iron overload and common...

iron fish, a small iron ingot used during cooking to provide dietary iron to those with iron deficiency. People with hemochromatosis (iron overload,...

diabetic ketoacidosis, low white blood cells, cancer, organ transplant, iron overload, kidney problems, long-term steroids or use of immunosuppressants, and...

brand name Exjade among others, is an oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood...

transferrin saturation: markers of iron overload as in hemochromatosis, copper and ceruloplasmin: markers of copper overload as in Wilson's disease Immunoglobulin...

retardation, aminoaciduria (amino acids in the urine), cholestasis, iron overload, lactic acidosis and early death. Prior to birth, the growth of the...

Look up overload or overloaded in Wiktionary, the free dictionary. Overload or overloaded may refer to: Overload (novel), a 1979 novel by Arthur Hailey...

accessing iron in the blood, which causes anemia that is apparent at birth. It can lead to pallor, fatigue, and slow growth. The iron overload aspect of...

serum iron being available for developing red blood cells. When the hepcidin level is abnormally low, such as in hemochromatosis, iron overload occurs...

in humans. Compounds of icariin, astragalus, and puerarin mitigates iron overload in the cerebral cortex of mice with Alzheimer's disease. Adverse effects...

viscosity Reduced net transfused volume of red blood cells, which reduces iron overload. However, there are also potential risks associated with an exchange...

event of known iron overload or iron utilization disorders. Iron polymaltose must not be administered at the same time as parenteral iron preparations....

forms of iron overload can be thought of as relative hepcidin deficiency in one way or another[1]. For instance, a severe form of iron overload, juvenile...