A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides...

Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins. Serine serves as the nucleophilic amino acid at the (enzyme's)...

Protease inhibitor can refer to: Protease inhibitor (pharmacology): a class of medication that inhibits viral protease Protease inhibitor (biology): molecules...

and COVID-19. These protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease) and blocking proteolytic...

Protease A may refer to one of two enzymes: Streptogrisin A Omptin This disambiguation page lists articles associated with the title Protease A. If an...

triads are most commonly found in hydrolase and transferase enzymes (e.g. proteases, amidases, esterases, acylases, lipases and β-lactamases). An acid-base-nucleophile...

Cysteine proteases, also known as thiol proteases, are hydrolase enzymes that degrade proteins. These proteases share a common catalytic mechanism that...

three proteases: P1 protease (1 cleavage site), helper-component protease (1 cleavage site) and TEV protease (7 cleavage sites). The native TEV protease also...

3C-like protease (3CLpro) or main protease (Mpro), formally known as C30 endopeptidase or 3-chymotrypsin-like protease, is the main protease found in...

in infectious material has a different structure and is resistant to proteases, the enzymes in the body that can normally break down proteins. The normal...

The rhomboid proteases are a family of enzymes that exist in almost all species. They are proteases: they cut the polypeptide chain of other proteins....

In molecular biology, Proteinase K (EC 3.4.21.64, protease K, endopeptidase K, Tritirachium alkaline proteinase, Tritirachium album serine proteinase,...

two classes of acidic proteases: Aspartic proteases - that use a catalytic aspartic acid in their active site Glutamic proteases - that use a catalytic...

In molecular biology, the Lon protease family is a family of enzymes that break peptide bonds in proteins resulting in smaller peptides or amino acids...

proteins with similar structures that were first identified for their protease inhibition activity and are found in all kingdoms of life. The acronym...

Protease-activated receptors (PAR) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular...

Variably protease-sensitive prionopathy (VPSPr) (formerly known as Protease Sensitive Prionopathy) is a sporadic prion protein disease first described...

(HIV protease inhibitor) Darunavir (HIV protease inhibitor) Delavirdine (non-nucleoside reverse transcriptase inhibitor) Fosamprenavir (HIV protease inhibitor)...

sixth catalytic type of protease. Members of this group of protease had been previously assumed to be an aspartate protease, but structural determination...

IgA protease may refer to: IgA specific serine endopeptidase, an enzyme IgA-specific metalloendopeptidase, an enzyme This set index page lists enzyme articles...

HIV-1 protease or PR is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential...

Zingibain, zingipain, or ginger protease (EC 3.4.22.67) is a cysteine protease enzyme found in ginger (Zingiber officinale) rhizomes. It catalyses the...

Threonine proteases are a family of proteolytic enzymes harbouring a threonine (Thr) residue within the active site. The prototype members of this class...

produce a favourable interaction. Many enzymes including serine protease, cysteine protease, protein kinase and phosphatase evolved to form transient covalent...

Serine protease 57 is a protein that in humans is encoded by the PRSS57 gene. This gene encodes an arginine-specific serine protease and member of the...

Proteases (also sometimes referred to as proteolytic enzymes or peptidases) are in use, or have been proposed or tried, for a number of purposes related...

ligands, like protease inhibitors, that can modulate catalytic activities has an enormous therapeutic effect. Hence, inhibition of the HIV protease is one of...

Aspartic proteases (also "aspartyl proteases", "aspartic endopeptidases") are a catalytic type of protease enzymes that use an activated water molecule...

study of proteases, their inhibitors, and their substrates on a system-wide scale. This includes the analysis of the protease and protease-substrate...

22.14, actinidin, Actinidia anionic protease, proteinase A2 of Actinidia chinensis) is a type of cysteine protease enzyme found in fruits including kiwifruit...