Protein structure is the three-dimensional arrangement of atoms in an amino acid-chain molecule. Proteins are polymers – specifically polypeptides – formed...

Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of...

Protein quaternary structure is the fourth (and highest) classification level of protein structure. Protein quaternary structure refers to the structure...

Protein primary structure is the linear sequence of amino acids in a peptide or protein. By convention, the primary structure of a protein is reported...

Protein tertiary structure is the three-dimensional shape of a protein. The tertiary structure will have a single polypeptide chain "backbone" with one...

Protein secondary structure is the local spatial conformation of the polypeptide backbone excluding the side chains. The two most common secondary structural...

Protein quinary structure refers to the features of protein surfaces that are shaped by evolutionary adaptation to the physiological context of living...

a protein structure database is a database that is modeled around the various experimentally determined protein structures. The aim of most protein structure...

of protein structure prediction software summarizes notable used software tools in protein structure prediction, including homology modeling, protein threading...

responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily...

Critical Assessment of Structure Prediction (CASP), sometimes called Critical Assessment of Protein Structure Prediction, is a community-wide, worldwide...

three-dimensional structure. This structure permits the protein to become biologically functional or active. The folding of many proteins begins even during...

powerful frameworks for protein structure prediction, protein–protein interaction, and free energy calculations for protein structures. Using a graphical model...

Protein biosynthesis, or protein synthesis, is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation...

computational biology, de novo protein structure prediction refers to an algorithmic process by which protein tertiary structure is predicted from its amino...

dynamic light scattering techniques. The spherical structure is induced by the protein's tertiary structure. The molecule's apolar (hydrophobic) amino acids...

and crystallization. In addition, structures of many water-soluble protein domains of IMPs are available in the Protein Data Bank. Their membrane-anchoring...

The genome and proteins of HIV (human immunodeficiency virus) have been the subject of extensive research since the discovery of the virus in 1983. "In...

three-dimensional structure. Many proteins consist of several domains, and a domain may appear in a variety of different proteins. Molecular evolution...

The Open Protein Structure Annotation Network (TOPSAN) is a wiki designed to collect, share and distribute information about protein three-dimensional...

DeepMind, a subsidiary of Alphabet, which performs predictions of protein structure. It is designed using deep learning techniques. AlphaFold 1 (2018)...

biology, an intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure, typically in the absence of its...

more polymer structures based on their shape and three-dimensional conformation. This process is usually applied to protein tertiary structures but can also...

Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to...

Antifreeze proteins (AFPs) or ice structuring proteins refer to a class of polypeptides produced by certain animals, plants, fungi and bacteria that permit...

With the determination of the first structure of the complex between a G-protein coupled receptor (GPCR) and a G-protein trimer (Gαβγ) in 2011 a new chapter...

The green fluorescent protein (GFP) is a protein that exhibits green fluorescence when exposed to light in the blue to ultraviolet range. The label GFP...

as proteins of known structures, but do not have homologous proteins with known structure. It differs from the homology modeling method of structure prediction...

DALI, use the 3D structure of a protein of interest to find proteins with similar folds. However, on rare occasions, related proteins may evolve to be...

understanding of protein function. Proteins can be designed from scratch (de novo design) or by making calculated variants of a known protein structure and its...