Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the bloodstream that is not associated with cells. ctDNA should not be confused with...

nucleases. The term cfDNA can be used to describe various forms of DNA freely circulating in body fluids, including circulating tumor DNA (ctDNA), cell-free mitochondrial...

Digital Error Suppression (iDES). The use of ctDNA in this technique should not be confused with circulating tumor cells (CTCs); these are two different entities...

biopsy of circulating tumor DNA for EGFR-mutated lung cancer is approved by the FDA. The CellSearch method for enumeration of circulating tumor cells in...

Circulating mitochondrial DNA, also called cell-free circulating mitochondrial DNA and circulating cell-free mitochondrial DNA (ccf mtDNA), are short...

cell-free circulating tumor DNA (cfDNA) has an advantage over circulating tumor cells assays in that there is approximately 100 times more cell-free DNA than...

in cancer patients. It primarily analyzes circulating tumor DNA (ctDNA)—small fragments of DNA shed from tumor cells into the blood plasma. This method...

developed new methods to detect and monitor the low levels of circulating tumor DNA (ctDNA) fragments released into the bloodstream of people who have cancer...

discovered a technique which "involves detecting and monitoring tumor fragments circulating in the patient's bloodstream", as an alternative to traditional...

minimal residual disease (MRD) using circulating tumor DNA (ctDNA) analysis that does not require prior sequencing of a tumor tissue. Instead, these assays analyze...

personalized profiling by deep sequencing (CAPP-Seq) for analysis of circulating tumor DNA (ctDNA). The CLiP technique integrates multiple distinctive genomic...

Derek (2017-08-16). "Direct detection of early-stage cancers using circulating tumor DNA". Science Translational Medicine. 9 (403). doi:10.1126/scitranslmed...

increased risk for common hereditary cancers. Signatera is the first circulating tumor DNA (ctDNA) assay built for molecular residual disease (MRD) detection and...

incidence of tumor DNA in the blood, which can both provide early detection of tumor growth and indicate relapse in cancer. Circulating tumor DNA can be found...

Hui (2019). "Molecular profiling of tumors of the brainstem by sequencing of CSF-derived circulating tumor DNA". Acta Neuropathologica. 137 (2): 297–306...

2014, Cancer research identified Circulating Tumor Cells (CTCs) and Circulating Tumor DNA (ctDNA) as metastasizing tumor biomarkers with special cellular...

cancer cells, known as circulating tumor cells (CTCs), are able to penetrate the walls of lymphatic or blood vessels, and circulate through the bloodstream...

hypermethylation of DNA. Carcinomas were determined to be caused by mutations in Wnt and p53 pathways. Both adenoma and carcinoma tumors of the adrenal cortex...

Wallis, M; Bentley, D; Caldas, C; Rosenfeld, N (2013). "Analysis of circulating tumor DNA to monitor metastatic breast cancer". New England Journal of Medicine...

the use of circulating tumor DNA (ctDNA) as a non-invasive biomarker. His laboratory has developed techniques for detecting and analyzing ctDNA, which can...

identified by analyzing mutational signatures from genomic sequencing of tumor DNA. For example, this can reveal if lung cancer was caused by tobacco smoke...

as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused...

monitor tumor load, treatment response and disease progression in cancer patients by measuring rare mutations in circulating tumor DNA (ctDNA) in a variety...

profiling, using techniques like liquid biopsy (e.g., circulating tumor DNA or ctDNA), can capture tumor-derived genetic material shed into blood or other...

i10-index of 355. His 10 most cited works include: Detection of circulating tumor DNA in early-and late-stage human malignancies, doi: 10.1126/scitranslmed...

Recently, molecular analysis on tumour DNA has gained growing popularity. Detection of ctDNA (circulating tumor DNA) within CSF offers promising directions...

(start, stop or change) DNA tests are based on detecting circulating tumor DNA in the blood that contains cancer-specific DNA sequences. Modern techniques...

plastid DNA, as well as many other varieties of extrachromosomal DNA, including plasmids and some viral DNA. Contrast linear DNA. circulating tumor DNA (ctDNA)...

Tumor necrosis factor (TNF), formerly known as TNF-α, is a chemical messenger produced by the immune system that induces inflammation. TNF is produced...

mosaicism, subclonal variants in genetically heterogeneous cancers, or circulating tumor DNA. Several library preparation strategies have been developed that...