Gap junctions were first described as close appositions alongside tight junctions, however, electron microscopy studies in 1967 led to gap junctions being...

A gap junction modulator is a compound or agent that either facilitates or inhibits the transfer of small molecules between biological cells by regulating...

of cell junction: Adherens junctions, desmosomes and hemidesmosomes (anchoring junctions) Gap junctions (communicating junction) Tight junctions (occluding...

Gap junction modulation describes the functional manipulation of gap junctions, specialized channels that allow direct electrical and chemical communication...

Gap junction proteins Gap junction α (GJA) proteins GJA1, Cx43, gap junction alpha-1 protein GJA2, Cx38, gap junction alpha-2 protein GJA3, Cx46, gap...

age. Gap-junction proteins, called connexins, expressed in the cochlea play an important role in auditory functioning. Mutations in gap-junction genes...

(TC# 1.A.24), or gap junction proteins, are structurally related transmembrane proteins that assemble to form vertebrate gap junctions. An entirely different...

Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the GJA1 gene on chromosome 6. As a connexin...

An electrical synapse, or gap junction, is a mechanical and electrically conductive synapse, a functional junction between two neighboring neurons. The...

synapses, neurons are coupled bidirectionally with each other through gap junctions and have a connected cytoplasmic milieu. These types of synapses are...

PMID 30288656. S2CID 52919432. Kurtenbach S, Kurtenbach S, Zoidl G (2014). "Gap junction modulation and its implications for heart function". Frontiers in Physiology...

an assembly of six proteins called connexins that form the pore for a gap junction between the cytoplasm of two adjacent cells. This channel allows for...

together and provide structural stability like anchoring junctions or tight junctions. Gap junction channels are selectively permeable to specific ions depending...

are the gap junctions, which are made of connexins which serve important functions in distribution and connection between cells; the gap junctions enable...

Gap junction beta-2 protein (GJB2), also known as connexin 26 (Cx26) — is a protein that in humans is encoded by the GJB2 gene. Gap junctions were first...

individual cells propagate across distances via electrical synapses known as gap junctions (conductors), which allow cells to share their resting potential with...

Gap junction beta-6 protein (GJB6), also known as connexin 30 (Cx30) — is a protein that in humans is encoded by the GJB6 gene. Connexin 30 (Cx30) is one...

other special cases. As models of brain function using only neuronal and gap junction connections fail to explain its complexity, ephaptic coupling is being...

bundles rather than single smooth muscle cells that are connected by gap junctions which allow electrotonic spread of activity between cells. A multiplicity...

Gap junction beta-1 protein (GJB1), also known as connexin 32 (Cx32), is a transmembrane protein that in humans is encoded by the GJB1 gene. Gap junction...

identified for this gene. Tight junction protein 1 has been shown to interact with: F11 receptor, GJA3, GJA8, Gap junction protein, alpha 1, KIRREL, MLLT4...

(such as adherens junctions, desmosomes, focal adhesions, and hemidesmosomes), and communicating junctions (such as gap junctions). The structures they...

mutation can appear in the GJB1 gene coding for the connexin 32 protein, a gap junction protein expressed in Schwann cells. Because this protein is also present...

Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens), are multiprotein junctional complexes between...

electrode voltage clamp, and is only used in the study of gap junction channels. Gap junctions are pores that directly link two cells through which ions...

Innexins are transmembrane proteins that form gap junctions in invertebrates. Gap junctions are composed of membrane proteins that form a channel permeable...

which is made possible due to the organism's efficient intercellular gap junction communication. While further studies have been proposed to further research...

keratin proteins. Desmosomes also play a role in cell-cell signaling. Gap junctions are the main site of cell-cell signaling or communication that allow...

conductive gap junctions between neurons. Gap junctions are critical for cardiac myocytes; mice and humans deficient in a particular gap junction protein...

vessel tone oscillation. Gap junctions are thought to play a large role in this synchronization, as application of gap junction blockers has been shown...