The norepinephrine transporter (NET), also known as noradrenaline transporter (NAT), is a protein that in humans is encoded by the solute carrier family...
33 KB (3,478 words) - 15:43, 11 January 2025
competitively and/or noncompetitively inhibiting the norepinephrine transporter (NET) and dopamine transporter (DAT). NDRIs are used clinically in the treatment...
5 KB (463 words) - 05:51, 28 January 2025
depression and attention deficit hyperactivity disorder (ADHD). The norepinephrine transporter (NET) serves as the fundamental mechanism for the inactivation...
34 KB (3,816 words) - 22:08, 29 May 2025
three major classes are serotonin transporters (SERTs), dopamine transporters (DATs), and norepinephrine transporters (NETs) and are responsible for the...
21 KB (2,342 words) - 15:34, 14 September 2024
inhibitors (SSRIs) and norepinephrine reuptake inhibitors (NRIs), which act upon single neurotransmitters. The human serotonin transporter (SERT) and noradrenaline...
84 KB (8,211 words) - 18:10, 23 May 2025
neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET). This in turn...
7 KB (678 words) - 15:01, 12 December 2024
cortex, where evidence points to a possibly larger role of the norepinephrine transporter. DAT is implicated in a number of dopamine-related disorders,...
84 KB (9,204 words) - 02:53, 2 June 2025
A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that induces the release of norepinephrine...
18 KB (1,747 words) - 15:13, 13 February 2025
Dopamine reuptake inhibitor (redirect from Dopamine transporter "inverse agonist")
very selective for the dopamine transporter, with little to no effect on the norepinephrine and serotonin transporters 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl...
19 KB (1,930 words) - 22:33, 23 May 2025
epinephrine and norepinephrine; subtypes include α1, α2, β1, β2, and β3 receptors Adrenergic transporter (norepinephrine transporter), a protein transporting...
3 KB (286 words) - 18:10, 25 July 2024
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and...
60 KB (6,685 words) - 12:18, 31 May 2025
(MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT). This in turn results in an increase...
20 KB (1,388 words) - 21:36, 30 January 2025
exceptionally difficult to tease apart affinity for the DAT from the norepinephrine transporter (NET) and inhibit the reuptake of dopamine alone. As a result...
16 KB (1,791 words) - 22:09, 29 May 2025
proteins for monoamines (i.e., the dopamine transporter, norepinephrine transporter, and serotonin transporter) in monoamine neurons. Other VMAT2 inhibitors...
29 KB (3,347 words) - 14:46, 25 May 2025
simultaneous inhibition of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT), respectively, increasing their...
142 KB (16,594 words) - 16:53, 5 June 2025
the monoamine transporters (SERTTooltip serotonin transporter, DATTooltip dopamine transporter, NETTooltip norepinephrine transporter). It is associated...
6 KB (378 words) - 11:29, 28 January 2024
Atomoxetine (category Serotonin–norepinephrine reuptake inhibitors)
Atomoxetine, formerly sold under the brand name Strattera, is a selective norepinephrine reuptake inhibitor (sNRI) medication used to treat attention deficit...
72 KB (6,260 words) - 04:34, 5 June 2025
Reuptake (category Neurotransmitter transporters)
of the transporters associated with important neurotransmitters within the body were also very similar in sequence to the GABA and norepinephrine transporters...
15 KB (1,897 words) - 08:15, 17 July 2024
autonomic cardiac neuropathy, although reduced expression of the norepinephrine transporter may also result in impaired MIBG reuptake and has been implicated...
99 KB (9,955 words) - 04:57, 6 June 2025
WY-46824 (category Norepinephrine–dopamine reuptake inhibitors)
of 46 nM for the norepinephrine transporter (NET), 58 nM for the dopamine transporter (DAT), and 18795 nM for the serotonin transporter (SERT). The racemic...
3 KB (195 words) - 15:43, 11 January 2025
inhibit serotonin transporter (SERT) in the brain and have negligible effects on dopamine transporter (DAT) and norepinephrine transporter (NET). Inhibiting...
51 KB (5,336 words) - 14:09, 1 April 2025
Reboxetine (category Norepinephrine reuptake inhibitors)
fairly selective norepinephrine reuptake inhibitor (NRI), with approximately 20-fold selectivity for the norepinephrine transporter (NET) over the serotonin...
29 KB (2,701 words) - 14:51, 18 April 2025
Methylphenidate (category Norepinephrine–dopamine reuptake inhibitors)
monoamine transporters when they are co-administered.[better source needed] Methylphenidate has both dopamine transporter and norepinephrine transporter binding...
155 KB (14,239 words) - 10:45, 6 June 2025
Membrane transport protein (redirect from Membrane transporter)
transporters (EAATs) EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 Glucose transporter Monoamine transporters, including: Dopamine transporter (DAT) Norepinephrine transporter...
26 KB (2,656 words) - 14:08, 8 March 2025
pharmacological profile, distinct from cocaine, at dopamine, serotonin, and norepinephrine transporter sites. The study highlighted that "hydrophobicity and conformational...
3 KB (260 words) - 23:18, 31 January 2025
the monoamine transporters (MATs), including the serotonin transporter (SERT), norepinephrine transporter (NET), and/or dopamine transporter (DAT), causing...
263 KB (22,099 words) - 23:59, 9 May 2025
transports monoamine neurotransmitters – such as dopamine, serotonin, norepinephrine, epinephrine, and histamine – into the vesicles, which release the neurotransmitters...
43 KB (4,993 words) - 04:26, 10 March 2025
(5-hydroxytryptamine, or 5-HT) by blocking the action of the serotonin transporter (SERT). This in turn leads to increased extracellular concentrations...
11 KB (843 words) - 10:04, 13 March 2024
inhibits serotonin transporter (SERT) and norepinephrine transporter (NET). It is metabolized to nortriptyline, a stronger norepinephrine reuptake inhibitor...
93 KB (8,721 words) - 03:43, 2 June 2025
Nisoxetine (category Norepinephrine reuptake inhibitors)
nisoxetine for positron emission tomography (PET) imaging of the norepinephrine transporter (NET), with little success. However, it seems that tritium labeled...
24 KB (2,777 words) - 15:51, 6 June 2025