Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside...

with the PROTAC itself being recycled after the target protein is degraded. The protein targeting warhead, E3 ligase, and linker must all be considered...

thylakoid proteins encoded by a plant's nuclear genome need two targeting signals for proper localization: An N-terminal chloroplast targeting peptide (shown...

which is referred to as uORFs (upstream open reading frames). Protein targeting Target peptide Topogenic sequence Kapp, Katja; Schrempf, Sabrina; Lemberg...

mammalian target of rapamycin (mTOR), also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated...

Protein folding is the physical process by which a protein, after synthesis by a ribosome as a linear chain of amino acids, changes from an unstable random...

Targeting may refer to: Gene targeting Protein targeting Behavioral targeting Targeted advertising Target market Geotargeting, in internet marketing Targeting...

molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein complexes. There are a...

Pea protein is a food product and protein supplement derived and extracted from yellow and green split peas, Pisum sativum. It can be used as a dietary...

Target proteins are functional biomolecules that are addressed and controlled by biologically active compounds. They are used in the processes of transduction...

Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical...

Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation...

target protein. The E3, which may be a multi-protein complex, is, in general, responsible for targeting ubiquitination to specific substrate proteins...

amphipathic helix. Mitochondrial targeting signals can contain additional signals that subsequently target the protein to different regions of the mitochondria...

KKXX (amino acid sequence) KDEL (amino acid sequence) Signal peptide Protein targeting Mariano Stornaiuolo; Lavinia V. Lotti; Nica Borgese; Maria-Rosaria...

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions...

unique protein targeting system to avoid having chloroplast proteins being sent to the wrong organelle. Polypeptides, the precursors of proteins, are chains...

Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their...

shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation...

kilodalton heat shock proteins (Hsp70s or DnaK) are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure...

universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets specific proteins to the endoplasmic reticulum in eukaryotes...

contain internal targeting signals, these signals have an indefinable nature and are inconsistent in their pattern. Proteins targeted to the outer membrane...

protein complex was a valid identification. If a particular protein can only be recovered by targeting one of the known members but not by targeting other...

bulk flow. [citation needed] Protein targeting Vesicle (biology) COPI COPII Mass flow 1. Rothman J.E. and Weiland F.T. Protein sorting by transport vesicles...

with ubiquitin, the subcellular localization of the protein is altered, often targeting the protein for destruction in lysosomes. This serves as a negative...

membrane. Binding of a protein to a specific lipid occurs via specific membrane-targeting structural domains that occur within the protein and have specific...

covalent process of changing proteins following protein biosynthesis. PTMs may involve enzymes or occur spontaneously. Proteins are created by ribosomes,...

cascade, protein-protein interactions and in mechanisms that regulate protein targeting and function. An example in which the myristoylation of a protein is...

specificity to allow selective targeting of proteins to intracellular degradation. In particular, parkin recognises proteins on the outer membrane of mitochondria...

sometimes called Critical Assessment of Protein Structure Prediction, is a community-wide, worldwide experiment for protein structure prediction taking place...