25-Hydroxycholesterol is a derivative of cholesterol, which plays a role in various biological processes in humans and other species. It is involved in...

Hydroxycholesterol may refer to: 7α-Hydroxycholesterol 20S-Hydroxycholesterol 22R-Hydroxycholesterol (22(R)-Hydroxycholesterol) Cerebrosterol (24(S)-Hydroxycholesterol)...

25-hydroxycholesterol 7alpha-hydroxylase (EC 1.14.13.100, 25-hydroxycholesterol 7alpha-monooxygenase, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase) is...

27-Hydroxycholesterol (27-HC) is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator...

(February 2022). "Senolysis induced by 25-hydroxycholesterol targets CRYAB in multiple cell types". iScience. 25 (2): 103848. Bibcode:2022iSci...25j3848L...

24S-Hydroxycholesterol (24S-HC), also known as cholest-5-ene-3,24-diol or cerebrosterol, is an endogenous oxysterol produced by neurons in the brain to...

25-hydroxycholesterol + A + H2O The 3 substrates of this enzyme are cholesterol, an electron acceptor AH2, and O2, whereas its 3 products are 25-hydroxycholesterol...

CYP450s, including: CYP7A1 (cholesterol 7α-hydroxylase) CYP7B1 (25-hydroxycholesterol 7α-hydroxylase) CYP8B1 (sterol 12α-hydroxylase) CYP11A1 (cholesterol...

25-hydroxycholesterol 7-alpha-hydroxylase also known as oxysterol and steroid 7-alpha-hydroxylase is an enzyme that in humans is encoded by the CYP7B1...

Its substrates include the oxysterols 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol. GRCh38: Ensembl release 89: ENSG00000146233...

Dhawan V (June 2010). "Role of 8-iso-prostaglandin F2alpha and 25-hydroxycholesterol in the pathophysiology of endometriosis". Fertility and Sterility...

been shown to be able to interact with Leydig cells by secreting 25-hydroxycholesterol, an oxysterol that can be converted to testosterone by neighbouring...

7α-Hydroxycholesterol is a precursor of bile acids, created by cholesterol 7α-hydroxylase (CYP7A1). Its formation is the rate-determining step in bile...

can quickly influence central nervous system function. 25-Hydroxycholesterol: cholest-5-en-3β,25-diol – NMDA receptor negative allosteric modulator 3α...

refer to: Hydroxycholesterols 7α-Hydroxycholesterol 22R-Hydroxycholesterol(22(R)-Hydroxycholesterol) Cerebrosterol (24(S)-Hydroxycholesterol) 25-Hydroxycholesterol...

22R-Hydroxycholesterol, or (3β)-cholest-5-ene-3,22-diol is an endogenous, metabolic intermediate in the biosynthesis of the steroid hormones from cholesterol...

Zheng S, Wada T, Xie W, Li Y (May 2010). "Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma". Molecular...

is an intracellular protein that was identified as a cytosolic 25-hydroxycholesterol-binding protein. OSBP is a lipid transfer protein that controls...

Deeley RG (September 2006). "ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells"...

against neuronal damage. Negative allosteric modulators include: 25-Hydroxycholesterol – endogenous weak negative allosteric modulator Conantokins – naturally...

maintaining normal testis function. They have been shown to secrete 25-hydroxycholesterol, a sterol that can be converted to testosterone by Leydig cells...

family (ORP). It was first described as the cytoplasmic receptor for 25-hydroxycholesterol, and after more than 20 years it was shown that it's a cholesterol...

8-oxocoformycin reductase - 12beta-hydroxysteroid dehydrogenase - 25-hydroxycholesterol 7α-hydroxylase - abietadiene hydroxylase - acrylamide gels - Act...

it is found in Kupffer cells. STARD5 binds both cholesterol and 25-hydroxycholesterol and appears to function to redistribute cholesterol to the endoplasmic...

20S-Hydroxycholesterol is a steroid of the oxysterol class. It is a human metabolite of cholesterol. 20S-Hydroxycholesterol has been the subject of research...

lipoproteins and reduce risk of risk of cardiovascular disease), 25-hydroxycholesterol, vitamin K, ketoconazole (an antifungal medication), sesamin (a...

Side chain oxygenated sterols (e.g., 20α-hydroxycholesterol, 22R-hydroxycholesterol, and 25-hydroxycholesterol) are high affinity RORγ agonists while sterols...

Muscat, G.E.O.; Stow, J.L. (2016). Bozza, P.T. (ed.). "RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages". PLOS...

weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants...

2002). "Oxysterol-binding-protein (OSBP)-related protein 4 binds 25-hydroxycholesterol and interacts with vimentin intermediate filaments". Biochem J....