The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine...
25 KB (2,993 words) - 19:47, 5 January 2025
cognition and memory. AS-19 is a 5-HT7 receptor agonist that has been used in scientific research. Serotonin receptor antagonist "Flibanserin: MedlinePlus...
16 KB (1,664 words) - 07:32, 20 February 2025
these receptors were "a heterogeneous population of 5-HT1B, 5-HT1D and 5-HT7" receptors the classification was redundant. Hoyer D, Clarke DE, Fozard JR, Hartig...
65 KB (5,270 words) - 07:14, 24 November 2024
5-HT3 receptors in cell lines and native tissues quickly followed. 5-HT1 receptor 5-HT2 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor...
22 KB (2,395 words) - 18:29, 18 July 2024
5-HT2A receptor 5-HT2B receptor 5-HT2C receptor 5-HT1 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor Category:5-HT2...
2 KB (166 words) - 00:47, 13 May 2022
206 nM affinity. SB-699,551 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT4 receptor 5-HT6 receptor 5-HT7 receptor GRCh38: Ensembl release...
16 KB (1,773 words) - 06:08, 29 April 2025
The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). The 5-HT2A...
95 KB (10,424 words) - 04:41, 27 April 2025
receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT1A...
59 KB (6,182 words) - 02:27, 19 January 2025
number of 5-HT receptor subtypes were involved in the IBS symptoms, including 5-HT3, 5-HT4, and 5-HT7 receptors. High levels of 5-HT7 receptor-expressing...
120 KB (13,033 words) - 07:26, 11 May 2025
Chamomile (ethanol extract) 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor GRCh38: Ensembl release...
18 KB (2,075 words) - 06:39, 29 April 2025
articles of the individual subtypes: 5-HT2 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor Hoyer D, Clarke DE, Fozard JR...
5 KB (472 words) - 12:54, 25 December 2023
Serotonin modulator and stimulator (category Serotonin receptor antagonists)
serotonin reuptake inhibitor (SRI), agonist of the 5-HT1A receptor, and antagonist of the 5-HT3 and 5-HT7 receptors. However, it can also technically be applied...
5 KB (568 words) - 17:03, 21 March 2024
and D3 receptor antagonist, serotonin 5-HT1A receptor partial agonist, serotonin 5-HT2A and 5-HT7 receptor antagonist, α2C-adrenergic receptor antagonist...
39 KB (3,147 words) - 13:32, 22 April 2025
Cyclobenzaprine (category 5-HT7 antagonists)
serotonin 5-HT2A, 5-HT2B, 5-HT2C, 5-HT6, and 5-HT7 receptor antagonism, α1- and α2-adrenergic receptor antagonism, histamine H1 receptor noncompetitive...
30 KB (2,408 words) - 21:34, 29 April 2025
Amisulpride (category 5-HT7 antagonists)
5-HT7 receptor (Ki = 11.5 nM). Several of the other atypical antipsychotics such as risperidone and ziprasidone are potent antagonists at the 5-HT7 receptor...
51 KB (4,343 words) - 05:13, 11 May 2025
full agonist at the 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5A, and 5-HT7 receptors, as well as an agonist of the 5-HT2, 5-HT3, 5-HT6 receptors with lower affinity...
7 KB (559 words) - 07:15, 27 March 2025
other actions) Masupirdine (SUVN-502) – 5-HT6 receptor antagonist N-Methylamisulpride (LB-102) – D2,3, 5-HT7, receptor antagonist (methylated version of amisulpride)...
10 KB (746 words) - 22:51, 27 February 2025
norepinephrine stabilizes mood in humans. 5-HT6 receptor antagonists improve cognition, learning, and memory. The 5-HT7 receptor is very potent for the mitigation...
102 KB (9,302 words) - 10:44, 1 May 2025
– atypical antipsychotic (dopamine D2 and D3 receptor antagonist and serotonin 5-HT2B and 5-HT7 receptor antagonist) SNG-12 (Synapsinae) – glycine transporter...
151 KB (11,540 words) - 10:10, 10 May 2025
SB-269970 (category 5-HT7 antagonists)
GlaxoSmithKline used in scientific studies. It is believed to act as a selective 5-HT7 receptor antagonist (EC50 = 1.25 nM) (or possibly inverse agonist). A subsequent...
6 KB (534 words) - 17:15, 21 January 2025
; Heredia, DJ.; Smith, TK. (Jul 2010). "Critical role of 5-HT1A, 5-HT3, and 5-HT7 receptor subtypes in the initiation, generation, and propagation of...
11 KB (1,085 words) - 16:49, 15 October 2024
Amesergide (category 5-HT7 antagonists)
of the serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptors (Ki = 1.96–15.1 nM). It is also an antagonist of the serotonin 5-HT7 receptor with relatively lower...
11 KB (635 words) - 09:07, 23 December 2023
E-55888 (category 5-HT7 agonists)
selective full agonist at the 5HT7 serotonin receptor, and is used for investigating the role of 5-HT7 receptors in the perception of pain. When administered...
3 KB (166 words) - 10:20, 13 September 2024
Vortioxetine (category 5-HT7 antagonists)
the serotonin 5-HT1A receptor, partial agonist of the 5-HT1B receptor, and antagonist of the serotonin 5-HT1D, 5-HT3, and 5-HT7 receptors, as well as an...
56 KB (4,812 words) - 17:40, 20 March 2025
N-Methylamisulpride (category 5-HT7 antagonists)
(developmental code name LB-102) is a dopamine D2 and D3 receptor antagonist and serotonin 5-HT2B and 5-HT7 receptor antagonist which is under development for the...
8 KB (639 words) - 05:52, 16 December 2024
SB-258719 (category 5-HT7 antagonists)
GlaxoSmithKline which acts as a selective 5-HT7 receptor partial inverse agonist, and was the first such ligand identified for 5-HT7. Its use in research has mainly...
5 KB (367 words) - 17:14, 21 January 2025
JRT (drug) (category 5-HT7 agonists)
serotonin 5-HT1A and 5-HT7 receptors, an antagonist of the serotonin 5-HT5A and 5-HT7 receptors, and binds to the serotonin 5-HT6 receptor. It does not...
11 KB (825 words) - 03:50, 12 May 2025
Aripiprazole (category 5-HT7 antagonists)
on presynaptic D2 receptors, D3, and partially D4 and is a partial activator of serotonin (5-HT1A, 5-HT2A, 5-HT2B, 5-HT6, and 5-HT7). It also shows lower...
107 KB (9,659 words) - 04:33, 28 April 2025
also a precursor of 5-MeO-DMT in some species. 5-MT acts as an agonist of the serotonin 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors. It is an extremely...
29 KB (2,572 words) - 07:44, 10 May 2025
rats using this compound while characterizing various agonists of the 5-HT7 receptor. It is an agonist with a Ki value of 630.96nM. It has been found to...
6 KB (393 words) - 14:37, 2 May 2025