Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A, also known as APOBEC3A, or A3A is a gene of the APOBEC3 family found in primates, including humans...
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where the original A-T base pair transforms into a G-C base pair. APOBEC1 APOBEC3A-H, APOBEC3G - affects HIV Activation-induced cytidine deaminase (AICDA)...
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encoding members of the APOBEC protein family include: APOBEC1 APOBEC2 APOBEC3A APOBEC3B APOBEC3C APOBEC3D ("APOBEC3E" now refers to this) APOBEC3F APOBEC3G...
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viral infections by editing viral genome, but the enzymatic activity of APOBEC3A and APOBEC3B has also been found to cause unwanted host genome editing...
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control. This gene along with APOBEC3A have been in recent years found associated with mutagenesis of several cancers. The APOBEC3A and APOBEC3B proteins can...
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HGNC:603 P04114 856 APOBEC1 HGNC:604 P41238 857 APOBEC2 HGNC:605 Q9Y235 858 APOBEC3A HGNC:17343 P31941 859 APOBEC3B HGNC:17352 Q9UH17 860 APOBEC3C HGNC:17353...
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G-to-A mRNA changes in WT1 transcripts at two hotspots, proposing the APOBEC3A (apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3A) as the...
61 KB (7,437 words) - 00:53, 7 March 2025
through two sets of enzymatic reactions using three enzymes TET2, T4-BGT and APOBEC3A. The method primarily detects 5-methylcytosine (5mC), the most common form...
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Davis J (September 2012). "Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients". Translational...
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was first identified by Jarmuz et al. as a member of family of proteins APOBEC3A to 3G on chromosome 22 in 2002 and later also as a cellular factor able...
26 KB (2,959 words) - 03:09, 1 December 2023
Haimov-Kochman, R., Nevo, Y., Stockheim, D., Yagel, S., Panet, A., Wolf, D.G., APOBEC3A is upregulated by human cytomegalovirus (HCMV) in the maternal-fetal interface...
14 KB (1,480 words) - 09:33, 10 May 2025
Fujiwara H, Yoshizaki T, Mori S, Kukimoto I, Muramatsu M (February 2015). "APOBEC3A and 3C decrease human papillomavirus 16 pseudovirion infectivity". Biochemical...
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underlying the maintenance of HIV latency. They found that the protein Apobec3A blocks HIV reactivation by binding to the region of HIV DNA that would...
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abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells". PLOS Biology. 19 (3): e3001176. doi:10...
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PMID 26109598. Hoopes JI, Cortez LM, Mertz TM, et al. (February 2016). "APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during...
75 KB (7,954 words) - 13:13, 2 November 2024