CIITA is a human gene which encodes a protein called the class II, major histocompatibility complex, transactivator. Mutations in this gene are responsible...

class II expression is closely regulated in APCs by CIITA, which is the MHC class II transactivator. CIITA is solely expressed on professional APCs; however...

type of N-terminal domain: NLRA (A for acidic transactivating domain): CIITA NLRB (B for BIRs): NAIP NLRC (C for CARD): NOD1, NOD2, NLRC3, NLRC4, NLRC5...

single master regulatory factor known as the class II transactivator (CIITA). CIITA is a non-DNA-binding co-activator whose expression is tightly controlled...

24% with Komo. The language is also called Opo-Shita, Opo, Opuo, Cita, Ciita, Shita (along with Dana), Shiita, Ansita, Kina, and Kwina. The self-name...

HGNC:1976 O60543 3059 CIDEB HGNC:1977 Q9UHD4 3060 CIDEC HGNC:24229 Q96AQ7 3061 CIITA HGNC:7067 P33076 3062 CILK1 HGNC:21219 Q9UPZ9 3063 CILP HGNC:1980 O75339...

Zinc finger, X-linked, duplicated family member C (ZXDC) is a human CIITA-binding protein involved in the activation of major histocompatibility complex...

other proteins the most important are: the MHC Class II transactivator (CIITA), IPAF, BIRC1 etc. The ligands are currently known for NOD1 and NOD2. NOD1...

proteins that contain it: NAIP (NLP family apoptosis inhibitor protein), CIITA (that is, C2TA or MHC class II transcription activator), HET-E (incompatibility...

prevent NK cells attacks due to deletion of HLA. Deletion of the B2M and CIITA genes using the CRISPR/Cas9 system has been reported to suppress the expression...

the general transcription factors TFIIE and TFIIF. Other proteins include CIITA, Brm (chromatin remodeler), NF-κB (p65), TAL1/SCL, Beta2/NeuroD, C/EBPβ...

Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. Proc Natl Acad Sci U S A...

in TAP1, TAP2, TAPBP, or B2M) MHC class II deficiency (with mutations in CIITA, RFXANK, RFX5, or RFXAP) CD25 deficiency CD27 deficiency STAT5b deficiency...

phosphorylated and ubiquitinated. MAPK1 has been shown to interact with: ADAM17, CIITA, DUSP1, DUSP3, ELK1, FHL2, HDAC4, MAP2K1, MAP3K1 MAPK14, MKNK1, MKNK2, Myc...

the synthesis of these proteins, the CIITA or class II transcription activator. Selective gene targeting of CIITA has been used ex vivo to allow MHC class...

histocompatibility class II (MHC II) DRA gene by IFN-gamma. Following induction of the CIITA transcription factor by IFN-gamma, there was recruitment of both CDK7 and...

cells from viruses including COVID-19 and Ebola. They found that one gene, CIITA, can help human cells resist the virus by activating another gene, CD74...

genes can lead to BLS II. The genes' names are: class II trans-activator (CIITA) regulatory factor X5 (RFX5) RFX-associated protein (RFXAP) RFX ankyrin...

of only two have been determined. RFX5 has been shown to interact with CIITA. GRCh38: Ensembl release 89: ENSG00000143390 – Ensembl, May 2017 GRCm38:...

of multiple myeloma. XPO1 has been shown to interact with: APC, CDKN1B, CIITA, NMD3, Nucleoporin 62, RANBP1, RANBP3, Ran, SMARCB1, and p53. Karyopherin...

class II molecule by direct expression cloning of the transcription factor CIITA". International Immunology. 7 (7): 1087–92. doi:10.1093/intimm/7.7.1087...

lymphocyte syndrome type II is due to mutations in any of the following genes: CIITA is responsible for giving instructions to create a protein that controls...

Paliwal I, et al. (2003). "Human trophoblast noncoding RNA suppresses CIITA promoter III activity in murine B-lymphocytes". Biochem. Biophys. Res. Commun...

domain and has been shown to interact with: Androgen receptor, C-Fos, C-jun, CIITA, CREB-binding protein, Cyclin D1, DDX17, DDX5 and Estrogen receptor alpha...

Egeland T, Undlien DE (September 2008). "Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency". The Journal...

Mahanta SK, Scholl T, Yang FC, Strominger JL (1997). "Transactivation by CIITA, the type II bare lymphocyte syndrome-associated factor, requires participation...

M, et al. (1998). "The RFX complex is crucial for the constitutive and CIITA-mediated transactivation of MHC class I and beta2-microglobulin genes"....

showing activation activity. RFXANK has been shown to interact with RFXAP and CIITA. GRCh38: Ensembl release 89: ENSG00000064490 – Ensembl, May 2017 GRCm38:...

a family of NLR proteins that includes the transcriptional co-activator CIITA and the canonical inflammasome protein NLRP3. A truncated murine NLRC4 was...

PRRs NOD-like receptors (NLRs) NLRA (A for acidic transactivating domain) CIITA NLRB (B for BIR, or Inhibitor of apoptosis domain) NAIP NLRC (C for CARD...