• Thumbnail for CRISPR gene editing
    CRISPR gene editing (/ˈkrɪspər/; pronounced like "crisper"; an abbreviation for "clustered regularly interspaced short palindromic repeats") is a genetic...
    177 KB (20,524 words) - 22:37, 29 May 2025
  • Thumbnail for He Jiankui affair
    addition, use of CRISPR gene editing (CRISPR/Cas9), a technology for modifying DNA. The embryos' genomes were edited to remove the CCR5 gene in an attempt...
    120 KB (12,426 words) - 15:33, 30 April 2025
  • Switzerland. It was one of the first companies formed to utilize the CRISPR gene editing platform to develop medicines for the treatment of various rare and...
    11 KB (920 words) - 11:02, 28 May 2025
  • Thumbnail for Jennifer Doudna
    February 19, 1964) is an American biochemist who has pioneered work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics...
    70 KB (6,070 words) - 02:03, 3 June 2025
  • Thumbnail for LEAPER gene editing
    than the CRISPR gene editing technique. Initial studies have claimed that editing efficiencies of up to 80%. As opposed to DNA gene editing techniques...
    7 KB (783 words) - 12:15, 22 February 2024
  • Thumbnail for CRISPR
    with CRISPR sequences form the basis of a technology known as CRISPR-Cas9 that can be used to edit genes within living organisms. This editing process...
    115 KB (11,900 words) - 23:21, 29 May 2025
  • Thumbnail for Genome editing
    regulations that anyone manipulating the human genome by gene-editing techniques, like CRISPR, would be held responsible for any related adverse consequences...
    79 KB (9,365 words) - 19:52, 22 May 2025
  • material in an organism's DNA to obtain desired results. Examples of gene editing are CRISPR, zinc finger nuclease, transcription activator-like effector nuclease...
    2 KB (317 words) - 20:14, 28 May 2024
  • specific genes without altering the underlying DNA sequence. Unlike traditional CRISPR-Cas9, which introduces double-strand breaks to edit genes, CRISPRa...
    22 KB (2,739 words) - 08:03, 1 April 2025
  • Thumbnail for Cas9
    Cas9 (redirect from CRISPR/Cas9)
    Biology portal Technology portal DCas9 activation system CRISPR CRISPR gene editing Genome editing Zinc finger nuclease Transcription activator-like effector...
    59 KB (7,257 words) - 05:11, 23 May 2025
  • Thumbnail for Cystinosis
    its safety and efficacy. CRISPR-Cas9 gene editing technology is being explored to directly correct the defective CTNS gene within a patient's own cells...
    21 KB (2,193 words) - 21:24, 28 May 2025
  • Thumbnail for Gene therapy
    studies of a CRISPR-based in vivo human gene editing therapy, where the editing takes place inside the human body. The first injection of the CRISPR-Cas System...
    184 KB (18,684 words) - 20:56, 29 May 2025
  • Thumbnail for Insert (molecular biology)
    cycle. CRISPR gene editing based on Clustered regularly interspaced short palindromic repeats (CRISPR) -Cas9 is an enzyme that uses the gene sequences...
    11 KB (1,360 words) - 02:06, 3 December 2023
  • Thumbnail for CRISPR interference
    CRISPR interference (CRISPRi) is a genetic perturbation technique that allows for sequence-specific repression of gene expression in prokaryotic and eukaryotic...
    24 KB (2,898 words) - 12:08, 22 March 2024
  • Thumbnail for Editas Medicine
    Editas Medicine (category Gene therapy)
    company which is developing therapies for rare diseases based on CRISPR gene editing technology. Editas headquarters is located in Cambridge, Massachusetts...
    16 KB (1,286 words) - 17:21, 25 May 2025
  • Thumbnail for Intellia Therapeutics
    enables highly precise editing of disease-causing genes directly within specific target tissues. Intellia's ex vivo programs use CRISPR to create the therapy...
    18 KB (1,662 words) - 16:31, 12 February 2025
  • nonprofit scientific research institute founded by Nobel laureate and CRISPR gene editing pioneer Jennifer Doudna and biophysicist Jonathan Weissman. The institute...
    38 KB (3,520 words) - 03:20, 3 June 2025
  • unlike them, is permanent. It works via base editing, a form of CRISPR gene editing. It is one of the first gene therapies that could be beneficial to a broad...
    3 KB (345 words) - 21:56, 14 April 2025
  • (gRNAs) for use with the CRISPR/Cas gene editing system. The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR associated nucleases)...
    16 KB (1,283 words) - 21:43, 2 January 2025
  • Thumbnail for Lei Stanley Qi
    CRISPR-Transcriptome Organization (CRISPR-TO) based on dCas13. Qi is a co-inventor of the University of California patent on the CRISPR gene-editing technology. Qi obtained...
    9 KB (676 words) - 03:18, 3 June 2025
  • winner of the 2020 Nobel Prize in Chemistry for her work on the CRISPR system of gene editing. On March 22, 2021, Isaacson appeared on The Late Show with...
    4 KB (301 words) - 01:16, 4 January 2025
  • Thumbnail for Gene drive
    genome edits that would affect the germline, including those related to CRISPR-Cas9 technologies, but supported continued basic research and gene editing that...
    47 KB (5,126 words) - 07:52, 25 May 2025
  • Thumbnail for Anti-CRISPR
    without being attacked by its immune system. CRISPR CRISPR/Cas Tools CRISPR gene editing Gene knockout Bacteriophage Phage therapy Genetics Bacteria Nakamura...
    32 KB (3,690 words) - 10:49, 25 May 2025
  • Broad Institute, where he contributed to early developments in CRISPR-based gene-editing technologies. After completing his doctorate, Hsu worked as a...
    9 KB (827 words) - 03:35, 19 May 2025
  • the Casφ and Cas14 families of CRISPR-associated enzymes, have demonstrated potential for therapeutic genome editing in in vivo settings. The company...
    7 KB (678 words) - 08:06, 10 May 2025
  • Thumbnail for Cas12a
    Cas12a (redirect from CRISPR/Cas12a)
    CRISPR-CAS9, TALENS and ZFNS – the battle in gene editing https://www.ptglab.com/news/blog/crispr-cas9-talens-and-zfns-the-battle-in-gene-editing/ Archived...
    22 KB (2,638 words) - 03:05, 25 May 2025
  • Thumbnail for Kiran Musunuru
    shown that the levels of the PCSK9 gene expression could be altered in the liver of mice using CRISPR-Cas9 gene editing technology, drastically reducing...
    15 KB (1,428 words) - 15:28, 25 May 2025
  • small clinical trial of CRISPR gene editing in which a – lipid nanoparticle formulated – CRISPR (with mCas9) gene editing therapeutic is injected in...
    280 KB (24,501 words) - 17:00, 22 May 2025
  • Thumbnail for Human genetic enhancement
    Phenotypic Impacts of CRISPR-Cas9 Editing in Mice Targeting the Tyr Gene: In a comprehensive CRISPR-Cas9 study on gene editing, the Tyr gene in mice was targeted...
    93 KB (10,228 words) - 20:00, 16 May 2025
  • Guide RNA (category Genome editing)
    double-stranded DNA and thereby can be used for gene editing. In bacteria and archaea, gRNAs are a part of the CRISPR-Cas system that serves as an adaptive immune...
    30 KB (3,644 words) - 14:03, 23 May 2025