A coactivator is a type of transcriptional coregulator that binds to an activator (a transcription factor) to increase the rate of transcription of a...
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Mediator is a multiprotein complex that functions as a transcriptional coactivator in all eukaryotes. It was discovered in 1990 in the lab of Roger D. Kornberg...
31 KB (3,502 words) - 04:27, 19 February 2024
PPARGC1A (redirect from PPARγ coactivator 1-α)
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is...
28 KB (3,324 words) - 06:25, 3 June 2024
The nuclear receptor coactivator 3 also known as NCOA3 is a protein that, in humans, is encoded by the NCOA3 gene. NCOA3 is also frequently called 'amplified...
21 KB (2,383 words) - 15:17, 11 October 2023
PPARG coactivator 1 alpha is a protein that in humans is encoded by the PPARGC1A gene. The protein encoded by this gene is a transcriptional coactivator that...
5 KB (637 words) - 08:17, 11 March 2024
The nuclear receptor coactivator 1 (NCOA1), also called steroid receptor coactivator-1 (SRC-1), is a transcriptional coregulatory protein that contains...
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CREB regulated transcription coactivator (CRTC) may refer to the following proteins and genes: CRTC1 CRTC2 CRTC3 CREB CRTC (disambiguation) This disambiguation...
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FRY like transcription coactivator is a protein that in humans is encoded by the FRYL gene. GRCh38: Ensembl release 89: ENSG00000075539 – Ensembl, May...
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PPARGC1B (redirect from PPARg coactivator-1b)
Peroxisome proliferator-activated receptor gamma coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene. PPARGC1A Peroxisome...
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The nuclear receptor coactivator 2 also known as NCoA-2 is a protein that in humans is encoded by the NCOA2 gene. NCoA-2 is also frequently called glucocorticoid...
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The p300-CBP coactivator family in humans is composed of two closely related transcriptional co-activating proteins (or coactivators): p300 (also called...
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Peroxisome proliferator-activated receptor gamma (redirect from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha)
peroxisome proliferator-activated receptor gamma with transcriptional coactivators". The Journal of Biological Chemistry. 275 (43): 33201–4. doi:10.1074/jbc...
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agonist) AF-2 binds either the N-terminal FXXFL motif intramolecularly or coactivator proteins (containing the LXXLL or preferably FXXFL motifs) A ligand dependent...
87 KB (9,673 words) - 02:09, 31 May 2024
peroxisome proliferator-activated receptor delta GW501516 PPAR gamma coactivator 1-alpha estrogen-related receptor γ GSK4716 NFE2L2 Canonical transient...
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interact with a number of coactivators. Coactivators are not just protein partners that connect sites together in a complex. Coactivators play an active role...
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NCOA5 (redirect from Nuclear receptor coactivator 5)
Nuclear receptor coactivator 5 (NCOA5), also known as coactivator independent of AF-2 function (CIA), is a protein that in humans is encoded by the NCOA5...
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or KAT3A, (where CREB is cAMP response element-binding protein) is a coactivator encoded by the CREBBP gene in humans, located on chromosome 16p13.3....
52 KB (5,272 words) - 09:56, 3 June 2024
Nuclear receptor (section Coactivators)
to the dimerization interface of the receptor and in addition, binds coactivator and corepressor proteins. The LBD also contains the activation function...
74 KB (6,675 words) - 05:46, 31 May 2024
microcomedone formation. The retinoid-receptor complex competes for coactivator proteins of AP-1, a key transcription factor involved in inflammation...
31 KB (2,940 words) - 06:07, 28 February 2024
repression, or suppression – decrease the rate of gene transcription coactivator – a protein (or a small molecule) that works with transcription factors...
258 KB (26,889 words) - 01:30, 13 June 2024
repression, or suppression – decrease the rate of gene transcription coactivator – a protein (or a small molecule) that works with transcription factors...
57 KB (21,502 words) - 18:17, 11 June 2024
variable, in statistics Mediator (coactivator), a multiprotein complex that functions as a transcriptional coactivator Endogenous mediator, proteins that...
1 KB (208 words) - 21:39, 15 February 2024
previously unidentified coactivators necessary for receptor-dependent gene transcription. In 1995, he successfully cloned the first coactivator, SRC-1, marking...
19 KB (2,089 words) - 16:37, 23 May 2024
repression, or suppression – decrease the rate of gene transcription coactivator – a protein (or a small molecule) that works with transcription factors...
266 KB (31,209 words) - 18:05, 30 May 2024
Estrogen receptor alpha (section Coactivators)
acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA". The EMBO Journal. 20 (6):...
60 KB (6,357 words) - 21:20, 29 March 2024
receptor coactivator 6 is a protein that in humans is encoded by the NCOA6 gene. The protein encoded by this gene is a transcriptional coactivator that can...
16 KB (1,890 words) - 01:13, 6 May 2024
repression, or suppression – decrease the rate of gene transcription coactivator – a protein (or a small molecule) that works with transcription factors...
59 KB (20,596 words) - 03:32, 11 June 2024
gamma (PPARγ), PRDM16, peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α), and Early B-Cell Factor-2 (EBF2). The list of molecules...
73 KB (8,489 words) - 02:45, 11 May 2024
not be corrected by supplementation with any coactivators known at the time, nor was the absent coactivator protein characterized, which left some in the...
128 KB (12,669 words) - 15:58, 14 June 2024
that exhibit HAT activity. These include p300/CBP, nuclear receptor coactivators (e.g., ACTR/SRC-1), TAFII250, TFIIIC, Rtt109, and CLOCK. p300/CBP are...
53 KB (6,148 words) - 05:00, 3 December 2023