Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...

cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments. C5b is important in late events of the complement cascade, an...

Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...

Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system...

Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system. Once activated, about 12-18...

the Complement system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein...

syndrome. It is designed to bind to and prevent the activation of complement component 5 (C5). Paroxysmal nocturnal hemoglobinuria is characterized by red...

treatment of people with paroxysmal nocturnal hemoglobinuria. It is a complement component 5 (C5) inhibitor. Crovalimab was approved for use in China in February...

Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...

with C1q and C1s form the C1 complex, which is the first component of the serum complement system. C1r is an enzyme that activates C1s to its active...

component of fresh serum. Ehrlich, therefore, named this heat-labile component "complement", because it is something in the blood that "complements"...

Complement component 6 is a protein that in humans is encoded by the C6 gene. Complement component 6 is a protein involved in the complement system. It...

spinal nerve 5 Complement component 5, a protein of the complement system C5-convertase, an enzyme which splits C5 into C5b Complement component 5a, an inflammatory...

Complement component 7 is a protein involved in the complement system of the innate immune system. C7 is part of the membrane attack complex (MAC) which...

complement inhibitor that is injected subcutaneously (under the skin). Zilucoplan is a cyclic peptide that binds to the protein complement component 5...

Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes...

treatment of people with paroxysmal nocturnal hemoglobinuria. It is a complement component 5 (C5) inhibitor. Crovalimab was approved for use in China in February...

alternative pathway is a type of cascade reaction of the complement system and is a component of the innate immune system, a natural defense against infections...

classical complement pathway is one of three pathways which activate the complement system, which is part of the immune system. The classical complement pathway...

cells, leading to cell lysis and death. The MAC is composed of the complement components C5b, C6, C7, C8 and several C9 molecules. A number of proteins participate...

the complement system led Bhakdi to the area of atherosclerosis. In 1989 he discovered through animal experiments that the complement component 5 is activated...

Eculizumab specifically binds to the terminal complement component 5, or C5, which acts at a late stage in the complement cascade. When activated, C5 is involved...

involved in antibody-dependent cellular cytotoxicity. Antibodies are a key component of the adaptive immune response, playing a central role in both in the...

Complement factor B is a protein that in humans is encoded by the CFB gene. This gene encodes complement factor B, a component of the alternative pathway...

Leiner disease remains unknown but biotin deficiency linked to Complement component 5 (a protein ) coded by the C5 gene plays a role. This disease is...

Complement control proteins are proteins that interact with components of the complement system. The complement system is tightly regulated by a network...

"Inherited deficiency of the ninth component of complement in man". J. Immunol. 125 (5): 2252–7. doi:10.4049/jimmunol.125.5.2252. PMID 7430628. S2CID 32575206...

Complement C4-A is a kind of the Complement component 4 protein that in humans is encoded by the C4A gene. This gene encodes the acidic form of complement...

Alternative-complement-pathway C3/C5 convertase (EC 3.4.21.47, complement component C3/C5 convertase (alternative), proenzyme factor B, properdin factor...

bacteria with blood plasma components to activate the complement cascade which then cleave C5a from Complement component 5. Thus, bacteria produce a family...