Deferiprone, sold under the brand name Ferriprox among others, is a medication that chelates iron and is used to treat iron overload in thalassaemia major...
11 KB (897 words) - 20:33, 29 May 2025
Nancy Olivieri (section Deferiprone controversy)
for Sick Children and the pharmaceutical company Apotex about the drug deferiprone. Olivieri was born to the Hamilton, Ontario, Doctor Fernando Olivieri...
11 KB (1,060 words) - 21:36, 29 May 2025
Management of thalassemia (section Deferiprone)
therapy to reverse iron overload, using drugs such as deferoxamine, deferiprone, or deferasirox; medication with the antioxidant indicaxanthin to prevent...
42 KB (4,633 words) - 03:46, 2 June 2025
Transfusion-dependent anemia (section Deferiprone)
treat iron overload and common iron chelators used are deferoxamine, deferiprone and deferasirox. Due to the complications of transfusions dependency...
25 KB (2,854 words) - 12:54, 23 May 2025
Gideon Koren (section Deferiprone controversy)
In 1996, a controversy erupted about the safety and effectiveness of deferiprone. Koren believed the drug was effective for certain patients. Nancy Olivieri...
19 KB (1,820 words) - 02:52, 3 June 2025
initially as a chelation therapy agent. Synthetic siderophores such as deferiprone and deferasirox have been developed, using the known structure of deferoxamine...
15 KB (2,024 words) - 22:31, 2 May 2025
being investigated as a neuroprotective treatment. Other therapies, like deferiprone, may reduce the abnormal accumulation of iron in PD. In contrast to other...
131 KB (14,203 words) - 23:07, 19 June 2025
(and, thus, who develop iron overload as a result) are deferasirox and deferiprone. A minimally invasive approach to hereditary hemochromatosis treatment...
47 KB (4,894 words) - 03:58, 9 June 2025
insufficient evidence that iron chelating agents such as deferoxamine and deferiprone improve outcomes of those with malaria falciparum infection. A 2022 clinical...
253 KB (26,814 words) - 09:50, 24 June 2025
may be treated by chelation therapy with the medications deferoxamine, deferiprone, or deferasirox. Deferoxamine is only effective as a daily injection...
33 KB (4,411 words) - 08:38, 21 March 2025
may be treated by chelation therapy with the medications deferoxamine, deferiprone, or deferasirox. Deferoxamine is only effective as a daily injection...
75 KB (7,680 words) - 06:19, 11 June 2025
Cambridge-educated chemist, took over the company. In 1995, Cipla launched Deferiprone, the world's first oral iron chelator. In 1999, Cipla joined the Indian...
22 KB (1,749 words) - 16:57, 5 June 2025
this degree of selectivity is very hard to achieve. The synthetic drug deferiprone achieves selectivity by having two oxygen donor atoms so that it binds...
60 KB (7,559 words) - 02:16, 16 June 2025
tetraacetic acid (calcium disodium versenate) (CaNa2-EDTA) lead poisoning Deferoxamine, Deferasirox and Deferiprone acute iron poisoning iron overload...
48 KB (4,654 words) - 01:30, 24 June 2025
may be treated by chelation therapy with the medications deferoxamine, deferiprone, or deferasirox. Deferoxamine is only effective as a daily injection...
36 KB (6,284 words) - 10:18, 28 May 2025
she publicly revealed her fears about the inadequacy of their drug, deferiprone. She sued them for libeling her; they sued her ($20 million) for libeling...
34 KB (3,502 words) - 20:00, 29 May 2025
medications have been subject to clinical trial including the iron chelator deferiprone. DaT scans, transcranial Doppler sonography (TCD), PET scans, and, in...
14 KB (1,097 words) - 15:46, 30 October 2024
iron chelator as Deferoxamine (or Desferrioxamine), Deferasirox and Deferiprone is useful. Deferoxamine is an iron-chelating compound, and excretion...
69 KB (7,338 words) - 12:27, 13 June 2025
and deferasirox for oral use. A third chelating agent is available, deferiprone, but it has limited utility in MDS patients because of a major side effect...
63 KB (6,528 words) - 15:52, 6 June 2025
continuous intravenous desferrioxamine (DFO), possibly combined with deferiprone (DFP). It aims to balance the rate of iron accumulation from blood transfusion...
12 KB (1,300 words) - 06:26, 24 November 2024
dalteparin and nadroparin, including their quality-assured biosimilars. Deferiprone is an alternative cryoprecipitate (not pathogen-reduced) is an alternative...
67 KB (4,835 words) - 23:03, 3 May 2025
presented. Patients with superficial siderosis are often treated with deferiprone (brand name is Ferriprox), a lipid-soluble iron chelator, as this medication...
13 KB (1,562 words) - 17:27, 14 March 2025
company began exploring making branded drugs of its own. One of them was deferiprone, a potential treatment for the blood disorder thalassemia. Trials were...
65 KB (7,173 words) - 12:26, 15 April 2025
only a limited efficacy, unlike small-molecular chelators (deferasirox, deferiprone, or deferoxamine), such an approach may have only minor side effects...
29 KB (3,685 words) - 21:08, 23 June 2025
"Long-term safety and effectiveness of iron chelation therapy with oral deferiprone in patients with thalassemia major". N. Engl. J. Med. 339 (7): 417–428...
139 KB (4,579 words) - 02:17, 23 June 2025
to be administered by IV route (intravenous infusion). Together with deferiprone, deferasirox seems to be capable of removing iron from cells (cardiac...
11 KB (772 words) - 20:32, 29 May 2025
MD 1978 Canadian hematologist, demonstrated the negative effects of deferiprone on the liver Stan Kutcher BA 1974, MA 1975, MD 1979 Canadian senator...
33 KB (3,331 words) - 00:02, 27 May 2025
dectaflur (INN) deditonium bromide (INN) Defencath deferasirox (USAN) deferiprone (INN) deferitrin (USAN) deferoxamine (INN) defibrotide (INN) Definity...
14 KB (586 words) - 23:15, 2 May 2025
QV03AB95 Apomorphine QV03AB96 Ropinirole V03AC01 Deferoxamine V03AC02 Deferiprone V03AC03 Deferasirox V03AE01 Polystyrene sulfonate V03AE02 Sevelamer V03AE03...
3 KB (370 words) - 00:33, 26 December 2023
Hopfner U, Aitzetmueller MM, Brett EA, Thor D, et al. (June 2020). "Deferiprone Stimulates Aged Dermal Fibroblasts Via HIF-1α Modulation". Aesthetic...
48 KB (4,885 words) - 05:23, 23 May 2025