• Thumbnail for Direct pathway
    The direct pathway, sometimes known as the direct pathway of movement, is a neural pathway within the central nervous system (CNS) through the basal ganglia...
    5 KB (540 words) - 03:38, 15 June 2023
  • Thumbnail for Medium spiny neuron
    phenotypes (characteristic types): D1-type MSNs of the direct pathway and D2-type MSNs of the indirect pathway. Most striatal MSNs contain only D1-type or D2-type...
    34 KB (4,043 words) - 04:11, 3 September 2023
  • Thumbnail for Nigrostriatal pathway
    The nigrostriatal pathway is a bilateral dopaminergic pathway in the brain that connects the substantia nigra pars compacta (SNc) in the midbrain with...
    25 KB (3,058 words) - 00:12, 27 April 2024
  • Thumbnail for Basal ganglia disease
    the direct pathway, the indirect pathway is regulated by striatal dopamine. D2 dopamine receptors inhibit transmission via the indirect pathway. D2 receptors...
    29 KB (3,235 words) - 01:46, 3 December 2023
  • Thumbnail for Indirect pathway
    voluntary movements. It operates in conjunction with the direct pathway. The indirect pathway originates in the D2 subtype of the striatal medium spiny...
    5 KB (626 words) - 06:42, 9 April 2024
  • Thumbnail for Basal ganglia
    the direct pathway needs to continue reverberating. The short indirect pathway has been proposed to, in a direct push pull antagonism with the direct pathway...
    56 KB (6,289 words) - 15:54, 22 January 2024
  • Thumbnail for Neural pathway
    lemniscus pathway Retinohypothalamic tract is a photic neural input pathway involved in the circadian rhythms Direct pathway of movement Indirect pathway of...
    10 KB (1,043 words) - 01:20, 5 April 2024
  • Thumbnail for Dopaminergic pathways
    pathway, the mesocortical pathway, the nigrostriatal pathway, and the tuberoinfundibular pathway. The mesolimbic pathway and the mesocortical pathway...
    47 KB (4,229 words) - 07:37, 3 June 2024
  • Thumbnail for Glycolysis
    Glycolysis is the metabolic pathway that converts glucose (C6H12O6) into pyruvate and, in most organisms, occurs in the liquid part of cells (the cytosol)...
    81 KB (8,694 words) - 03:13, 7 June 2024
  • Thumbnail for Internal globus pallidus
    this pathway only contains one synapse (from the striatum to the internal globus pallidus), it is known as the direct pathway. The direct pathway is modulated...
    8 KB (942 words) - 14:23, 3 April 2024
  • Thumbnail for Metabolic pathway
    In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The reactants, products, and intermediates of an...
    25 KB (2,988 words) - 05:07, 7 June 2024
  • Thumbnail for Cortico-basal ganglia-thalamo-cortical loop
    inhibition of the thalamus. The second pathway, is called the direct (or Go) pathway and is excitatory. This pathway inhibits the GPi, resulting in the disinhibition...
    14 KB (1,784 words) - 09:38, 6 August 2023
  • Thumbnail for Lateral geniculate nucleus
    Neurons of the LGN send their axons through the optic radiation, a direct pathway to the primary visual cortex. In addition, the LGN receives many strong...
    24 KB (2,883 words) - 01:50, 3 June 2024
  • Thumbnail for Substantia nigra
    activity via the direct pathway exerts an inhibitory effect on neurons in the (SNpr) but an excitatory effect via the indirect pathway. The direct and indirect...
    43 KB (5,063 words) - 11:01, 22 March 2024
  • Thumbnail for Effects of climate change on mental health
    There are three broad pathways by which these effects can take place: directly, indirectly or via awareness. The direct pathway includes stress-related...
    52 KB (6,242 words) - 19:18, 19 May 2024
  • Thumbnail for Soundproofing
    between a sound source and any form of adjoining mass, hindering the direct pathway for sound transfer. The energy density of sound waves decreases as they...
    22 KB (2,538 words) - 04:17, 6 June 2024
  • Thumbnail for Pentose phosphate pathway
    pentose phosphate pathway (also called the phosphogluconate pathway and the hexose monophosphate shunt and the HMP Shunt) is a metabolic pathway parallel to...
    11 KB (1,112 words) - 17:58, 6 May 2024
  • Thumbnail for Hyperkinesia
    ganglia–thalamocortical circuitry. Overactivity of a direct pathway combined with decreased activity of indirect pathway results in activation of thalamic neurons...
    45 KB (5,754 words) - 10:57, 15 February 2024
  • Thumbnail for Mevalonate pathway
    The mevalonate pathway, also known as the isoprenoid pathway or HMG-CoA reductase pathway is an essential metabolic pathway present in eukaryotes, archaea...
    9 KB (756 words) - 21:39, 21 November 2023
  • The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain. The pathway connects the ventral tegmental...
    29 KB (3,487 words) - 18:05, 24 September 2023
  • Thumbnail for Hypokinesia
    movement. Two possible neural pathways enable the basal ganglia to produce movement. When activated, the direct pathway sends sensory and motor information...
    34 KB (3,472 words) - 16:36, 28 February 2024
  • Thumbnail for External globus pallidus
    inhibition. As the pathway from the striatum to the medial globus pallidus is monosynaptic (containing one synapse), it is called the direct pathway. The indirect...
    5 KB (507 words) - 14:23, 3 April 2024
  • Thumbnail for Shikimate pathway
    The shikimate pathway (shikimic acid pathway) is a seven-step metabolic pathway used by bacteria, archaea, fungi, algae, some protozoans, and plants for...
    5 KB (479 words) - 09:18, 2 June 2024
  • Thumbnail for Reward system
    pathways. The medial forebrain bundle, which is a set of many neural pathways that mediate brain stimulation reward (i.e., reward derived from direct...
    103 KB (13,122 words) - 13:07, 26 March 2024
  • Thumbnail for Globus pallidus
    the basal ganglia, with principal inputs from the striatum, and principal direct outputs to the thalamus and the substantia nigra. The latter is made up...
    12 KB (1,303 words) - 07:23, 4 April 2024
  • Thumbnail for Striatum
    primary input is to the basal ganglia system. Additionally, the mesolimbic pathway projects from the ventral tegmental area to the nucleus accumbens of the...
    51 KB (5,743 words) - 00:09, 11 April 2024
  • the indirect (non-lexical) pathway is preserved. However, the direct (lexical) pathway of reading is not. The indirect pathway of reading allows individuals...
    5 KB (508 words) - 12:22, 17 February 2024
  • The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface...
    24 KB (3,068 words) - 07:21, 7 June 2024
  • Thumbnail for Circulatory system
    chamber of the heart must arrive at the left chamber but there is no direct pathway between them. The thick septum of the heart is not perforated and does...
    50 KB (5,591 words) - 01:52, 21 May 2024
  • Thumbnail for Entner–Doudoroff pathway
    supporting the presence of the pathway in cyanobacteria, ferns, algae, mosses, and plants. Specifically, there is direct evidence that Hordeum vulgare...
    18 KB (2,106 words) - 04:58, 5 February 2024