Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches. They are selective...

rizatriptan and nasal zolmitriptan are the most used triptans for migraines in children. Triptans should be taken as soon as possible after the onset of pain...

review found rizatriptan to be more efficacious and tolerable than sumatriptan. Rizatriptan and other triptans can cause vasoconstriction, they are contraindicated...

a successor to cimetidine, and supported the development of the triptans. Gertrude Elion, working mostly with a group of fewer than 50 people on purine...

effectiveness of zolmitriptan in both men and women. Zolmitriptan is a more lipophilic compound with greater central permeability than certain other triptans like...

Eltoprazine is under development for the treatment of aggression and for other indications. In addition to being 5-HT1B agonists, triptans (i.e. sumatriptan...

inhibitors Nucleoside and nucleotide reverse transcriptase inhibitors PDE5 inhibitors Proton pump inhibitors Renin inhibitors Triptans TRPV1 antagonists c-Met...

role of the therapist was minimized in favor of patient self-discovery accompanied by MDMA induced feelings of empathy. Depression, substance use disorders...

established the League for Spiritual Discovery with LSD as its sacrament. Stanislav Grof has written that religious and mystical experiences observed during...

PMID 7658447. Saxena PR, Tfelt-Hansen P (2006). "Triptans, 5-HT1B/1D Receptor Agonists in the Acute Treatment of Migraine". In Olesen J (ed.). The Headaches...

Galvan, M.; Gittos, M.; Fatmi, M. (October 1996). "DISCOVERY OF 5-HT3 RECEPTOR ANTAGONISTS AND DOLASETRON MESILATE". EJHP Journal (6): 10–11. Archived...

(DXM), tramadol, tapentadol, pethidine (meperidine) and triptans and with drugs that impair metabolism of serotonin (including MAOIs).[citation needed] Serotonin...

drug discovery (PDF), doi:10.21203/rs.3.rs-2667175/v1, retrieved March 18, 2025 Gainetdinov RR, Hoener MC, Berry MD (July 2018). "Trace Amines and Their...

Analogue-based Drug Discovery. John Wiley & Sons. p. 460. ISBN 9783527607495. World Health Organization (2019). World Health Organization model list of essential...

PMC 3055340. PMID 20130535. Gillman PK (February 2010). "Triptans, serotonin agonists, and serotonin syndrome (serotonin toxicity): a review". Headache...

rabbit and human lung during the early 1970s. Selectivity rather than sensitivity proved to be a challenge for some TLC methods with the discovery in 1974–1975...

Vargas MV, Sun J, Hwang IW, et al. (May 2021). "Psychedelic-inspired drug discovery using an engineered biosensor". Cell. 184 (10): 2779–2792.e18. doi:10...

Joseph MH, Kochen W, Steinhart H (eds.), "Hopkins and the Discovery of Tryptophan", Progress in Tryptophan and Serotonin Research 1986, Berlin, Boston: De Gruyter...

amphetamine, MDMA, triptans, buspirone, ginseng, dextromethorphan (DXM), linezolid, tramadol, serotonin–norepinephrine reuptake inhibitors (SNRIs), and other SSRIs...

amphetamine and cocaine, selective serotonin reuptake inhibitors, and triptans. Bupropion (a component of Auvelity) may increase blood pressure and lead to...

agonist and serotonergic psychedelic which is under development for use at non-hallucinogenic doses in the treatment of psychiatric disorders and neuroinflammation...

discovery and development Zatosetron Ricasetron Bemesetron Tropanserin Granisetron Müller W, Stratz T (2004). "Local treatment of tendinopathies and myofascial...

PMID 10336564. Lieber CS (October 2004). "The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role". Drug Metabolism Reviews...

George SR, Setola V, Lee DK, Cheng R, et al. (March 2001). "Discovery of a novel member of the histamine receptor family". Molecular Pharmacology. 59 (3):...

as antidepressants in the early 1950s. The discovery of the 2 isoenzymes of MAO has led to the development of selective MAOIs that may have a more favorable...

chemist William Ramsay and English chemist Morris Travers on July 12, 1898, shortly after their discovery of the elements krypton and neon. They found xenon...

SNRIs, tricyclic antidepressants (TCAs), triptans, tramadol, tryptophan, buspirone, St John's wort, fentanyl, and lithium, among others. However, vortioxetine...

antipsychotics, triptans, cold medications containing dextromethorphan, and some herbal products such as St. John's wort. Concurrent use of 5-HT3 antagonists...

published his discovery in the book Experiments and Observations on Different Kinds of Air (1775), where he described how to produce the preparation of "nitrous...

(September 2005). "Assessment of the feasibility of oral controlled release in an exploratory development setting". Drug Discovery Today. 10 (17): 1159–1166...