Eukaryotic initiation factors (eIFs) are proteins or protein complexes involved in the initiation phase of eukaryotic translation. These proteins help...
13 KB (1,595 words) - 17:00, 27 August 2024
Eukaryotic initiation factor 3 (eIF3) is a multiprotein complex that functions during the initiation phase of eukaryotic translation. It is essential for...
22 KB (2,101 words) - 01:49, 14 June 2024
EIF2 (redirect from Eukaryotic initiation factor-2b)
Eukaryotic Initiation Factor 2 (eIF2) is a eukaryotic initiation factor. It is required for most forms of eukaryotic translation initiation. eIF2 mediates...
13 KB (1,538 words) - 19:25, 25 May 2025
EIF4E (redirect from Eukaryotic translation initiation factor 4E)
Eukaryotic translation initiation factor 4E, also known as eIF4E, is a protein that in humans is encoded by the EIF4E gene. Most eukaryotic cellular mRNAs...
65 KB (7,496 words) - 05:28, 28 May 2025
Eukaryotic initiation factor 4F (eIF4F) is a heterotrimeric protein complex that binds the 5' cap of messenger RNAs (mRNAs) to promote eukaryotic translation...
7 KB (707 words) - 05:35, 18 January 2025
factors): Many structural domains have been conserved through evolution, as prokaryotic initiation factors share similar structures with eukaryotic factors...
12 KB (1,418 words) - 14:36, 25 May 2025
EIF4G (redirect from Eukaryotic initiation factor 4G)
Eukaryotic translation initiation factor 4 G (eIF4G) is a protein involved in eukaryotic translation initiation and is a component of the eIF4F cap-binding...
8 KB (1,074 words) - 01:25, 9 January 2023
ribosomal subunit by eukaryotic initiation factor 2 (eIF2). It hydrolyzes GTP, and signals for the dissociation of several factors from the small ribosomal...
16 KB (1,940 words) - 09:46, 9 March 2025
Eukaryotic translation initiation factor 4E-binding protein 1 (also known as 4E-BP1) is a protein that in humans is encoded by the EIF4EBP1 gene. inhibits...
22 KB (2,696 words) - 20:21, 26 May 2025
Eukaryotic translation initiation factor 4 gamma 1 is a protein that in humans is encoded by the EIF4G1 gene. The protein encoded by this gene is a component...
13 KB (1,672 words) - 03:36, 23 December 2023
Eukaryotic translation initiation factor 2-alpha kinase 3, also known as protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), is an enzyme...
12 KB (1,365 words) - 06:21, 24 December 2023
Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene. It is the only known protein to contain the unusual...
11 KB (1,336 words) - 19:19, 25 March 2025
The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the...
16 KB (1,828 words) - 07:58, 10 March 2024
Eukaryotic translation initiation factor 5 is a protein that in humans is encoded by the EIF5 gene. EIF5 is a GTPase-activating protein. GRCh38: Ensembl...
7 KB (895 words) - 22:57, 27 December 2023
for translation initiation in a cap-independent manner, as part of the greater process of protein synthesis. Initiation of eukaryotic translation nearly...
19 KB (1,775 words) - 01:59, 24 May 2025
N (Feb 2011). "Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1". Science. 331 (6018): 730–736. Bibcode:2011Sci...
40 KB (3,975 words) - 03:29, 17 May 2025
Eukaryotic initiation factor 4A-I (also known as eIF4A1 or DDX2A) is a 46 kDa cytosolic protein that, in humans, is encoded by the EIF4A1 gene, which is...
24 KB (2,591 words) - 04:53, 26 May 2025
Eukaryotic translation initiation factor 2 subunit 1 (eIF2α) is a protein that in humans is encoded by the EIF2S1 gene. The protein encoded by this gene...
13 KB (1,448 words) - 22:56, 26 May 2025
translation Initiation factors. It was first detected at the very C-termini of the yeast protein GCD6, eIF-2B epsilon, and two other eukaryotic translation...
6 KB (639 words) - 09:54, 1 May 2024
Eukaryotic translation initiation factor 4E-binding protein 2 is a protein that in humans is encoded by the EIF4EBP2 gene. EIF4EBP2 knockout mice have...
5 KB (666 words) - 21:52, 12 August 2023
Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the EIF3A gene. It is one of the subunits of Eukaryotic...
12 KB (1,367 words) - 01:10, 29 March 2024
Eukaryotic translation initiation factor 3 subunit F (eIF3f) is a protein that in humans is encoded by the EIF3F gene. EIF3F has been shown to interact...
8 KB (1,014 words) - 01:12, 29 March 2024
Eukaryotic translation initiation factor 2A (eIF2A) is a protein that in humans is encoded by the EIF2A gene. The eIF2A protein is not to be confused with...
8 KB (1,000 words) - 23:11, 2 December 2023
the incorporation of free nucleotides into double-stranded DNA. Initiation of eukaryotic DNA replication is the first stage of DNA synthesis where the DNA...
121 KB (14,916 words) - 04:06, 3 January 2025
Eukaryotic translation initiation factor 3 subunit B (eIF3b) is a protein that in humans is encoded by the EIF3B gene. EIF3B has been shown to interact...
8 KB (952 words) - 05:24, 25 May 2025
Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene. eIF4B has been shown to interact with and stimulate...
8 KB (957 words) - 12:15, 1 August 2023
PABP) is an RNA-binding protein which triggers the binding of eukaryotic initiation factor 4 complex (eIF4G) directly to the poly(A) tail of mRNA which...
15 KB (1,980 words) - 07:45, 17 February 2024
Eukaryotic translation initiation factor 2 subunit 2 (eIF2β) is a protein that in humans is encoded by the EIF2S2 gene. Eukaryotic translation initiation...
10 KB (1,035 words) - 10:00, 17 October 2022
Eukaryotic translation initiation factor 3 subunit D (eIF3d) is a protein that in humans is encoded by the EIF3D gene. Eukaryotic translation initiation...
10 KB (1,093 words) - 10:29, 16 February 2025
Eukaryotic translation initiation factor 4E-binding protein 3 is a protein that in humans is encoded by the EIF4EBP3 gene. This gene encodes a member of...
4 KB (495 words) - 08:47, 13 August 2023