An exoribonuclease is an exonuclease ribonuclease, which are enzymes that degrade RNA by removing terminal nucleotides from either the 5' end or the 3'...

5′-3′ exoribonuclease 1 (Xrn1) is a protein that in humans is encoded by the XRN1 gene. Xrn1 hydrolyses RNA in the 5′ to 3′ direction. This gene encodes...

Exoribonuclease II (EC 3.1.13.1, ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, exoribonuclease (misleading)...

RNase R, or Ribonuclease R, is a 3'-->5' exoribonuclease, which belongs to the RNase II superfamily, a group of enzymes that hydrolyze RNA in the 3' -...

components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub-classes within the EC 2.7 (for the phosphorolytic...

RNase D is one of the seven exoribonucleases identified in E. coli. It is a 3'-5' exoribonuclease which has been shown to be involved in the 3' processing...

5'-3' Exoribonuclease 2 (XRN2) also known as Dhm1-like protein is an exoribonuclease enzyme that in humans is encoded by the XRN2 gene. The human gene...

Exoribonuclease H (EC 3.1.13.2) is an enzyme. This enzyme catalyses the following chemical reaction 3'-end directed exonucleolytic cleavage of viral RNA-DNA...

multi-protein exosome complex, which consists largely of 3′ to 5′ exoribonucleases. RNA polymerase II is known to be in effect during transcriptional...

coronavirus genome is a non-structural protein, nsp14, that is a 3’-to-5’ exoribonuclease (ExoN). This protein resides in the protein complex nsp10-nsp14 that...

as RNA-dependent RNA polymerase (nsp12), RNA helicase (nsp13), and exoribonuclease (nsp14). A number of the nonstructural proteins coalesce to form a...

large nidoviruses encode both a 2'-O-methyltransferase and a 3'–5' exoribonuclease (ExoN)—the latter being very unusual for an RNA virus. They also encode...

The protein nsp14 is a 3'-5' exoribonuclease which provides extra fidelity to the replication process. The exoribonuclease provides a proofreading function...

for enriching 2'-O-Methylations guided by C/D snoRNAs by using RNA exoribonuclease (Mycoplasma genitalium RNase R, MgR) and periodate oxidation reactivity...

further increasing specificity. A member of the larger DEDD family of exoribonucleases, RNAse T plays a key role in the maturation of tRNA as well as the...

Nucleotidyltransferases (EC 2.7.7) Enzymes that have phosphorolytic 3' to 5' exoribonuclease activity (break phosphodiester bond) RNase PH Polynucleotide Phosphorylase...

Exon, a region of DNA that is represented in the mature form of RNA Exoribonuclease or ExoN, an RNA degrading enzyme Exoniensis or Exon., the Post-Nominal...

all belong to the RNase PH family of RNases and are phosphorolytic exoribonucleases, meaning that they use inorganic phosphate to remove nucleotides from...

likely possess replication proofreading mechanisms in the form of an exoribonuclease within nonstructural protein nsp14. Positive-strand RNA viruses have...

towards the bound RNA polymerase II. This exonuclease is XRN2 (5'-3' Exoribonuclease 2) in humans. This model proposes that XRN2 proceeds to degrade the...

Phosphorylase (PNPase) is a bifunctional enzyme with a phosphorolytic 3' to 5' exoribonuclease activity and a 3'-terminal oligonucleotide polymerase activity. That...

viral RNA-dependent RNA polymerase and evades proofreading by viral exoribonuclease (ExoN), causing a decrease in viral RNA production. In some viruses...

nidovirus lineages, also lack methyltransferases as well as a proofreading exoribonuclease, a domain that is conserved in nidoviruses with larger genomes. This...

Heck AJ, Raijmakers R, Pruijn GJ (July 2010). "Dis3-like 1: a novel exoribonuclease associated with the human exosome". EMBO J. 29 (14): 2358–67. doi:10...

producing 5'-phosphomonoesters EC 3.1.13: Exoribonucleases producing 5'-phosphomonoesters EC 3.1.14: Exoribonucleases producing 3'-phosphomonoesters EC 3.1...

ontology Molecular function 3'-5'-exoribonuclease activity single-stranded DNA 3'-5' exodeoxyribonuclease activity exoribonuclease II activity metal ion binding...

to RNase PH is called an RNase PH domain (RPD). Two highly related exoribonuclease complexes: Polynucleotide phosphorylase Exosome complex Ishii R, Nureki...

binding protein binding exoribonuclease activity, producing 5'-phosphomonoesters RNA binding hydrolase activity 5'-3' exoribonuclease activity telomerase...

KIAA1008, RRP44, dis3p, DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease External IDs OMIM: 607533; MGI: 1919912; HomoloGene: 6910; GeneCards:...

initiated by the removal of the 5’ cap followed by degradation by XRN1, an exoribonuclease enzyme. The other pathway by which mRNA is degraded is by deadenylation...