• Thumbnail for Exosome component 1
    protein 46. Exosome component 1 has been shown to interact with: Exosome component 5, Exosome component 6, and Exosome component 7. GRCh38: Ensembl release...
    7 KB (782 words) - 05:46, 19 July 2025
  • Thumbnail for Exosome component 10
    Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...
    7 KB (858 words) - 17:16, 16 July 2025
  • Thumbnail for Exosome component 7
    component 7 has been shown to interact with: Exosome component 1, Exosome component 2, and Exosome component 6. GRCh38: Ensembl release 89: ENSG00000075914...
    6 KB (717 words) - 04:09, 15 July 2025
  • Thumbnail for Exosome component 6
    component 6 has been shown to interact with Exosome component 7,Exosome component 8 and Exosome component 1. GRCh38: Ensembl release 89: ENSG00000223496 –...
    4 KB (516 words) - 17:16, 16 July 2025
  • Thumbnail for Exosome component 2
    Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...
    8 KB (1,045 words) - 16:32, 17 July 2025
  • Thumbnail for Exosome component 5
    Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...
    9 KB (971 words) - 05:46, 19 July 2025
  • Thumbnail for Exosome component 8
    Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex. Exosome component 8 has been shown...
    6 KB (614 words) - 17:16, 16 July 2025
  • Thumbnail for Exosome component 4
    Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...
    6 KB (777 words) - 05:46, 19 July 2025
  • Thumbnail for Exosome component 3
    Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...
    6 KB (702 words) - 21:41, 15 July 2025
  • Thumbnail for Exosome component 9
    Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...
    8 KB (797 words) - 05:46, 19 July 2025
  • Thumbnail for Exosome complex
    The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...
    43 KB (4,589 words) - 17:33, 6 November 2024
  • Thumbnail for Telomerase RNA component
    transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1 hypermethylation the 5'-methylguanosine...
    23 KB (2,549 words) - 18:46, 16 July 2025
  • Thumbnail for Serum amyloid P component
    The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
    6 KB (744 words) - 18:35, 16 July 2025
  • Autoantibodies often found in these patients are the anti-PM/Scl (anti-exosome) antibodies. The symptoms that are seen most often are typical symptoms...
    6 KB (597 words) - 04:26, 20 June 2025
  • Thumbnail for Mucin-1
    transmembrane receptors, and extracellular components. The intercellular interaction between MUC-1 and the receptor ICAM-1 facilitates endothelial and epithelial...
    16 KB (2,027 words) - 23:45, 23 May 2025
  • degradation due to the combined activity of poly-adenylating polymerases and exosome complexes. CUT transcription occurs through RNA Polymerase II and initiates...
    18 KB (2,296 words) - 10:27, 5 January 2024
  • Thumbnail for Complement component 3
    Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...
    15 KB (1,758 words) - 16:58, 16 July 2025
  • Thumbnail for GJA1
    is encoded by the GJA1 gene on chromosome 6. As a connexin, GJA1 is a component of gap junctions, which allow for gap junction intercellular communication...
    18 KB (1,938 words) - 21:44, 15 July 2025
  • Thumbnail for Alpha-enolase
    Alpha-enolase (redirect from Enolase 1)
    Enolase 1 (ENO1), more commonly known as alpha-enolase, is a glycolytic enzyme expressed in most tissues, one of the isozymes of enolase. Each isoenzyme...
    17 KB (1,940 words) - 02:40, 16 June 2025
  • Thumbnail for Dicer
    Dicer (redirect from DCR-1)
    (RISC), which is essential for RNA interference. RISC has a catalytic component Argonaute, which is an endonuclease capable of degrading messenger RNA...
    26 KB (3,275 words) - 16:20, 17 July 2025
  • Thumbnail for TACSTD2
    TACSTD2 (redirect from EGP-1)
    Fujimaki T, Kanai A (2004). "Mutations in the membrane component, chromosome 1, surface marker 1 (M1S1) gene in gelatinous drop-like corneal dystrophy"...
    11 KB (1,362 words) - 07:27, 19 July 2025
  • Thumbnail for Polymeric immunoglobulin receptor
    Polymeric immunoglobulin receptor (category Genes on human chromosome 1)
    signals. During transcytosis, an essential part of pIgR, the secretory component, is attached to the ligand and later cleaved with the ligand to form fully...
    20 KB (2,421 words) - 06:58, 19 July 2025
  • Thumbnail for Complement receptor 1
    National Library of Medicine. "Entrez Gene: CR1 complement component (3b/4b) receptor 1 (Knops blood group)". Moulds JM, Nickells MW, Moulds JJ, Brown...
    22 KB (2,904 words) - 16:58, 16 July 2025
  • Thumbnail for Sepiapterin reductase
    gene. Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase; EC 1.1.1.153) catalyzes the NADPH-dependent reduction of various carbonyl substances...
    13 KB (1,348 words) - 07:15, 19 July 2025
  • Thumbnail for Fibrillin-1
    large, extracellular matrix glycoprotein that serves as a structural component of 10–12 nm calcium-binding microfibrils. These microfibrils provide force...
    29 KB (3,496 words) - 16:35, 17 July 2025
  • Thumbnail for Cyclooxygenase-1
    Cyclooxygenase 1 (COX-1), also known as prostaglandin-endoperoxide synthase 1 (HUGO PTGS1), is an enzyme that in humans is encoded by the PTGS1 gene. In...
    18 KB (2,133 words) - 04:03, 15 July 2025
  • Thumbnail for Glutathione reductase
    glutathione reductase has been implicated in the oxidative burst, a component of the immune response. The oxidative burst is a defense mechanism in...
    31 KB (3,697 words) - 12:39, 23 June 2025
  • Thumbnail for Gamma-butyrobetaine dioxygenase
    "Multiple forms of gamma-butyrobetaine hydroxylase (EC 1.14.11.1)". The Biochemical Journal. 223 (1): 119–27. doi:10.1042/bj2230119. PMC 1144272. PMID 6497835...
    26 KB (2,784 words) - 21:43, 15 July 2025
  • Thumbnail for VCAM-1
    Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that...
    6 KB (789 words) - 18:56, 16 July 2025
  • Thumbnail for Plasminogen activator inhibitor-1
    thrombosis in patients with these conditions. PAI-1 can induce cellular senescence. PAI-1 can also be a component of the senescence-associated secretory phenotype...
    13 KB (1,603 words) - 11:49, 17 July 2025