A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number...

Frameshift mutations can occur as de novo mutations in both prezygotic and postzygotic stages of development. For example, if a frameshift mutation occurs...

Ribosomal frameshifting, also known as translational frameshifting or translational recoding, is a biological phenomenon that occurs during translation...

specifics of the mutation. These consequences can range from no effect (e.g. synonymous mutations) to deleterious effects (e.g. frameshift mutations), with regard...

stem stronger and perfects the inverted repeat, it also creates a frameshift mutation in the nucleotide sequence which alters the reading frame and will...

causing insertions or deletions of base pairs, which cause frameshift mutations. These mutations can render the gene in which they occur nonfunctional, thus...

Frameshift mutations will alter all the amino acids encoded by the gene following the mutation. Usually, insertions and the subsequent frameshift mutation...

multiple of 3, it will produce a frameshift mutation. For example, a common microindel which results in a frameshift causes Bloom syndrome in the Jewish...

follows:: 39–50 : 109  Deleterious mutation: The change is proven to cause significant risks. Often, these are frameshift mutations that prevent the cell from...

as possible causes. Progressive retinal atrophy (PRA) caused by a frameshift mutation in the RPRG locus of the X chromosome. The disease leads to a slowly...

may alter splicing of the mRNA (splice site mutation), or cause a shift in the reading frame (frameshift), both of which can significantly alter the gene...

single base insertion or deletion would shift the reading frame (frameshift mutation) in such a way that the remaining DNA would code for a different...

FC40 has a high rate of mutation, and so is useful for studies, such as for adaptive mutation. Due to a frameshift mutation, a change in the sequence...

of three mutations that created a dysfunctional tyrosinase. Two of those mutations involve an insertion of a thymine (T), a frameshift mutation, resulting...

"Two novel frameshift mutations causing premature stop codons in a patient with the severe form of Maroteaux-Lamy syndrome". Human Mutation. 7 (4): 361–3...

of genes, through ways like a stop-gain mutation. PTV is sometime categorized under the umbrella term frameshift or truncating variants (FTVs), which includes...

NMD plays a role in the regulation of immunogenic frameshift-derived antigens. Frameshift mutations often result in the production of aberrant proteins...

2004 by a group of researchers led by Dr. Hansell Stedman, that a frameshift mutation shrank the individual muscle fibers of the temporalis muscle, which...

produce a stop codon, which is much less likely to happen. A recessive frameshift mutation resulting in a reduction of leptin has been observed in two consanguineous...

et al. (April 1999). "Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited...

neonatal progeroid syndrome-like lipodystrophy associated with a novel frameshift mutation at the 3-prime terminus of the FBN1-gene". Am. J. Med. Genet. 152A...

neonatal progeroid syndrome-like lipodystrophy associated with a novel frameshift mutation at the 3' terminus of the FBN1-gene". American Journal of Medical...

is similar to OI. Type XII – OI caused by a frameshift mutation in SP7 on chromosome 12q13.13. This mutation causes bone deformities, fractures, and delayed...

inactivating mutations in the NF2 gene located at 22q12.2 of chromosome 22, type of mutations vary and include protein-truncating alterations (frameshift deletions/insertions...

spread of cancer. The root cause of FAP is understood to be a genetic mutation—a change in the body's tumour suppressor genes that prevent development...

bits. In genetics, a framing error (also called a frameshift or a frameshift mutation) is a mutation that inserts or deletes a single nucleotide from a...

called missense mutations. Other types of mutations include frameshift mutations such as insertions or deletions. Some forms of mutations are hereditary...

germline mutations in these genes are found in about 15% of women with ovarian cancer. The most common mutations in BRCA1 and BRCA2 are the frameshift mutations...

Crohn's than the general population. The first mutation found to be associated with Crohn's was a frameshift in the NOD2 gene (also known as the CARD15 gene)...

It is due to a deletion in exon 16 of the GALC gene that causes a frameshift mutation leading to a premature stop codon. The GALC gene, found on chromosome...