Genome-wide complex trait analysis (GCTA) Genome-based restricted maximum likelihood (GREML) is a statistical method for heritability estimation in genetics...
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In genomics, a genome-wide association study (GWA study, or GWAS), is an observational study of a genome-wide set of genetic variants in different individuals...
72 KB (7,011 words) - 00:57, 24 June 2025
for genome-wide interaction analysis (GWIA) of case-control SNP data and analysis of quantitative traits Precision Mapping of Quantitative Trait Loci...
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using mixed effects models implemented in software such as genome-wide complex trait analysis (GCTA). To do this, researchers find the average genetic relatedness...
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Heritability (redirect from Heritable trait)
Goddard ME, Visscher PM (January 2011). "GCTA: a tool for genome-wide complex trait analysis". American Journal of Human Genetics. 88 (1): 76–82. doi:10...
47 KB (5,644 words) - 00:19, 21 July 2025
Polygenic score (redirect from Genome-wide score)
individual's phenotype. The PGS is also called the polygenic index (PGI) or genome-wide score; in the context of disease risk, it is called a polygenic risk...
60 KB (6,735 words) - 17:57, 17 July 2025
studied with statistical techniques like quantitative trait loci (QTL) mapping, and genome-wide association studies (GWAS) on a large scale. The overall...
27 KB (2,719 words) - 06:51, 25 June 2025
Gene-environment interaction Gene-environment correlation Genome-wide complex trait analysis Heritability Heritability of IQ Human nature Identical Strangers:...
67 KB (7,951 words) - 19:23, 23 June 2025
examining both human and pig quantitative trait loci through a method known as genome-wide complex trait analysis (GCTA), which allowed the researchers to...
23 KB (2,688 words) - 05:18, 19 July 2025
was supported by the introduction of Genome-wide complex trait analysis (GCTA) in 2010, which demonstrated that trait similarity could be predicted by the...
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Bacterial genome size Cryoconservation of animal genetic resources DNA methylation Genome Browser Genome Compiler Genome topology Genome-wide association...
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prioritization of candidate causal genes in candidate gene analysis following genome-wide association studies. TWAS looks at the RNA products of a specific...
22 KB (2,971 words) - 16:55, 24 June 2025
An epigenome-wide association study (EWAS) is an examination of a genome-wide set of quantifiable epigenetic marks, such as DNA methylation, in different...
32 KB (3,597 words) - 00:07, 10 July 2025
influence multiple pain-related traits. A study that conducted a genome-wide association joint analysis of 17 pain-related traits revealed that many of the...
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(August 2016). "Genome-wide association study using whole-genome sequencing rapidly identifies new genes influencing agronomic traits in rice". Nature...
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Goddard, M. E.; Visscher, P. M. (2011). "GCTA: A tool for genome-wide complex trait analysis". The American Journal of Human Genetics. 88 (1): 76–82. doi:10...
11 KB (783 words) - 06:00, 20 March 2023
R.; Jaffe, Andrew E. (2021-09-02). "Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia...
58 KB (6,253 words) - 22:18, 15 July 2025
Genetics (redirect from Genetic trait)
to look for locations in the genome that are associated with diseases, a method especially useful for multigenic traits not clearly defined by a single...
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polymorphism heritability of behavior problems in childhood: genome-wide complex trait analysis". Journal of the American Academy of Child & Adolescent Psychiatry...
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Personal genomics (redirect from Genome analysis)
the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different...
40 KB (4,463 words) - 04:36, 15 July 2025
based on summary statistics from genome-wide association studies (GWASs). The approach involves using regression analysis to examine the relationship between...
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personality traits, also known as the five-factor model (FFM) or the OCEAN model, is the prevailing model for personality traits. When factor analysis (a statistical...
24 KB (2,999 words) - 05:15, 2 March 2025
Bioinformatics (section Genome annotation)
provides. Genome-wide association studies have successfully identified thousands of common genetic variants for complex diseases and traits; however,...
133 KB (8,523 words) - 14:27, 29 July 2025
CRISPR gene editing (category Genome editing)
system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing...
181 KB (20,908 words) - 13:53, 25 July 2025
In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand...
33 KB (3,862 words) - 18:08, 23 July 2025
in validation of genome-wide association study (GWAS) results, breeding, prediction of traits, and discovering the etiology of traits & diseases. They...
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Metagenomics (redirect from Community genome)
Function-driven analysis seeks to identify clones expressing a desired trait or useful activity, followed by biochemical characterization and sequence analysis. This...
89 KB (9,246 words) - 20:21, 14 July 2025
Genetic linkage (redirect from Linkage analysis)
Daly; Hirschhorn, Joel N. (2005-02-01). "Genome-wide association studies for common diseases and complex traits". Nature Reviews Genetics. 6 (2): 95–108...
31 KB (4,032 words) - 19:24, 23 July 2025
Hayles J, Kim D, Wood V, Park HO, Won M, et al. (June 2010). "Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces...
31 KB (3,310 words) - 02:17, 7 June 2025
Andre Franke (section Genome wide association study)
Thomas C.G. Bosch. His dissertation was titled "A systematic genome-wide association analysis for Inflammatory Bowel Diseases." Following his doctor rerum...
20 KB (1,630 words) - 15:52, 17 July 2025