• Genome-wide complex trait analysis (GCTA) Genome-based restricted maximum likelihood (GREML) is a statistical method for heritability estimation in genetics...
    32 KB (3,510 words) - 17:14, 5 June 2024
  • Thumbnail for Genome-wide association study
    In genomics, a genome-wide association study (GWA study, or GWAS), is an observational study of a genome-wide set of genetic variants in different individuals...
    72 KB (7,011 words) - 00:57, 24 June 2025
  • for genome-wide interaction analysis (GWIA) of case-control SNP data and analysis of quantitative traits Precision Mapping of Quantitative Trait Loci...
    30 KB (3,609 words) - 16:53, 26 March 2025
  • using mixed effects models implemented in software such as genome-wide complex trait analysis (GCTA). To do this, researchers find the average genetic relatedness...
    83 KB (8,028 words) - 01:10, 3 July 2025
  • Thumbnail for Heritability
    Heritability (redirect from Heritable trait)
    Goddard ME, Visscher PM (January 2011). "GCTA: a tool for genome-wide complex trait analysis". American Journal of Human Genetics. 88 (1): 76–82. doi:10...
    47 KB (5,644 words) - 00:19, 21 July 2025
  • Thumbnail for Polygenic score
    individual's phenotype. The PGS is also called the polygenic index (PGI) or genome-wide score; in the context of disease risk, it is called a polygenic risk...
    60 KB (6,735 words) - 17:57, 17 July 2025
  • Thumbnail for Complex traits
    studied with statistical techniques like quantitative trait loci (QTL) mapping, and genome-wide association studies (GWAS) on a large scale. The overall...
    27 KB (2,719 words) - 06:51, 25 June 2025
  • Thumbnail for Twin study
    Gene-environment interaction Gene-environment correlation Genome-wide complex trait analysis Heritability Heritability of IQ Human nature Identical Strangers:...
    67 KB (7,951 words) - 19:23, 23 June 2025
  • examining both human and pig quantitative trait loci through a method known as genome-wide complex trait analysis (GCTA), which allowed the researchers to...
    23 KB (2,688 words) - 05:18, 19 July 2025
  • was supported by the introduction of Genome-wide complex trait analysis (GCTA) in 2010, which demonstrated that trait similarity could be predicted by the...
    14 KB (1,730 words) - 01:44, 11 July 2025
  • Thumbnail for Genome
    Bacterial genome size Cryoconservation of animal genetic resources DNA methylation Genome Browser Genome Compiler Genome topology Genome-wide association...
    44 KB (4,932 words) - 18:09, 22 July 2025
  • prioritization of candidate causal genes in candidate gene analysis following genome-wide association studies. TWAS looks at the RNA products of a specific...
    22 KB (2,971 words) - 16:55, 24 June 2025
  • Thumbnail for Epigenome-wide association study
    An epigenome-wide association study (EWAS) is an examination of a genome-wide set of quantifiable epigenetic marks, such as DNA methylation, in different...
    32 KB (3,597 words) - 00:07, 10 July 2025
  • Thumbnail for Pleiotropy
    influence multiple pain-related traits. A study that conducted a genome-wide association joint analysis of 17 pain-related traits revealed that many of the...
    50 KB (5,951 words) - 02:12, 19 July 2025
  • Thumbnail for Whole genome sequencing
    (August 2016). "Genome-wide association study using whole-genome sequencing rapidly identifies new genes influencing agronomic traits in rice". Nature...
    115 KB (9,592 words) - 17:15, 22 July 2025
  • Thumbnail for Michael Goddard
    Goddard, M. E.; Visscher, P. M. (2011). "GCTA: A tool for genome-wide complex trait analysis". The American Journal of Human Genetics. 88 (1): 76–82. doi:10...
    11 KB (783 words) - 06:00, 20 March 2023
  • Thumbnail for Single-nucleotide polymorphism
    R.; Jaffe, Andrew E. (2021-09-02). "Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia...
    58 KB (6,253 words) - 22:18, 15 July 2025
  • Thumbnail for Genetics
    Genetics (redirect from Genetic trait)
    to look for locations in the genome that are associated with diseases, a method especially useful for multigenic traits not clearly defined by a single...
    99 KB (10,492 words) - 21:21, 31 July 2025
  • polymorphism heritability of behavior problems in childhood: genome-wide complex trait analysis". Journal of the American Academy of Child & Adolescent Psychiatry...
    19 KB (2,246 words) - 15:31, 11 December 2023
  • the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different...
    40 KB (4,463 words) - 04:36, 15 July 2025
  • based on summary statistics from genome-wide association studies (GWASs). The approach involves using regression analysis to examine the relationship between...
    7 KB (799 words) - 07:04, 3 December 2023
  • personality traits, also known as the five-factor model (FFM) or the OCEAN model, is the prevailing model for personality traits. When factor analysis (a statistical...
    24 KB (2,999 words) - 05:15, 2 March 2025
  • Thumbnail for Bioinformatics
    provides. Genome-wide association studies have successfully identified thousands of common genetic variants for complex diseases and traits; however,...
    133 KB (8,523 words) - 14:27, 29 July 2025
  • Thumbnail for CRISPR gene editing
    CRISPR gene editing (category Genome editing)
    system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing...
    181 KB (20,908 words) - 13:53, 25 July 2025
  • In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand...
    33 KB (3,862 words) - 18:08, 23 July 2025
  • in validation of genome-wide association study (GWAS) results, breeding, prediction of traits, and discovering the etiology of traits & diseases. They...
    50 KB (5,728 words) - 07:15, 2 June 2025
  • Thumbnail for Metagenomics
    Function-driven analysis seeks to identify clones expressing a desired trait or useful activity, followed by biochemical characterization and sequence analysis. This...
    89 KB (9,246 words) - 20:21, 14 July 2025
  • Daly; Hirschhorn, Joel N. (2005-02-01). "Genome-wide association studies for common diseases and complex traits". Nature Reviews Genetics. 6 (2): 95–108...
    31 KB (4,032 words) - 19:24, 23 July 2025
  • Thumbnail for Phenotype
    Hayles J, Kim D, Wood V, Park HO, Won M, et al. (June 2010). "Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces...
    31 KB (3,310 words) - 02:17, 7 June 2025
  • Thumbnail for Andre Franke
    Thomas C.G. Bosch. His dissertation was titled "A systematic genome-wide association analysis for Inflammatory Bowel Diseases." Following his doctor rerum...
    20 KB (1,630 words) - 15:52, 17 July 2025