Lactase persistence or lactose tolerance is the continued activity of the lactase enzyme in adulthood, allowing the digestion of lactose in milk. In most...
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the recent evolution of lactase persistence in some cultures, which extends lactose tolerance into adulthood. Lactase persistence evolved in several populations...
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lactose in breast milk or formula. Some population segments exhibit lactase persistence resulting from a mutation that is postulated to have occurred 5,000–10...
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Western Steppe Herders (section Lactase persistence)
had a frequency of over 25% of an allele that is associated with lactase persistence, conferring lactose tolerance into adulthood. Steppe-derived populations...
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History of North Africa (section Lactase Persistence)
Africa and the Near East, may have been the source population for lactase persistence variants, including –13910*T, and may have been subsequently supplanted...
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to contagious diseases (such as malaria), light skin, blue eyes, lactase persistence (or the ability to digest milk after weaning), lower blood pressure...
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hair, and dark or dark-to-black skin, with no genetic adaption for lactase persistence into adulthood. The near-complete skeleton, an adult male who probably...
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Polymorphism 13.9 kb Upstream of the Lactase Gene (LCT) (C−13.9kbT) Does Not Predict or Cause the Lactase-Persistence Phenotype in Africans". The American...
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products. The ability for adult humans to digest milk relies on lactase persistence, so lactose intolerant individuals have trouble digesting lactose...
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lactose intolerance, and specifically the presence of the -13910T lactase persistence mutation, found in Europe and Central Asia, across South Asia. In...
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Genetic history of Africa (section Lactase persistence)
Africa and the Near East, may have been the source population for lactase persistence variants, including –13910*T, and may have been subsequently supplanted...
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tested. It has been hypothesized that an allele associated with lactase persistence (conferring lactose tolerance into adulthood) was brought to Europe...
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Swallow, Dallas M.; Thomas, Mark G. (2011-03-27). "Evolution of lactase persistence: an example of human niche construction". Philosophical Transactions...
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Ségurel, Laure; Bon, Céline (31 August 2017). "On the Evolution of Lactase Persistence in Humans". Annual Review of Genomics and Human Genetics. 18 (1):...
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Sarah Tishkoff (section Lactase persistence)
three new single-nucleotide polymorphisms (SNPs) associated with lactase persistence (G/C-14010, T/G-13915 and C/G-13907) among ethnic groups in East...
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Culture can profoundly influence gene frequencies in a population. Lactase persistence One of the best known examples is the prevalence of the genotype...
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East Asian types of ADH1B associated with rice domestication, or lactase persistence, are due to recent selection pressures. An even more recent adaptation...
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on lactase persistence polymorphism of 23 elite and commoner samples from the 10-11th century found that their low prevalence of lactase persistence "corresponds...
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Africa and the Middle East, may have been the source population for lactase persistence variants, including –13910*T, and may have been subsequently supplanted...
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Allele age (section Lactase persistence)
condition known as lactase persistence. A study conducted by Sarah Tishkoff and her team shows that the mutation for lactase persistence has been under positive...
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extensively on the evolution of lactase persistence (see Lactose intolerance), the ability of some humans to produce the enzyme lactase throughout their adult...
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(2009). "On the edge of Bantu expansions: MtDNA, Y chromosome and lactase persistence genetic variation in southwestern Angola". BMC Evolutionary Biology...
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Africa and the Near East, may have been the source population for lactase persistence variants, including –13910*T, and may have been subsequently supplanted...
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disease: 53 Hypercholesterolemia: 53 Krabbe disease[citation needed] Lactase persistence (dominant) Leber's hereditary optic neuropathy[citation needed] Lesch–Nyhan...
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0132088. PMC 4503422. PMID 26176541. Cramer DW (November 1989). "Lactase persistence and milk consumption as determinants of ovarian cancer risk". American...
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of Indian and European Cattle Share their Predominant Allele for Lactase Persistence". Mol. Biol. Evol. 29 (1): 249–260. doi:10.1093/molbev/msr190. PMID 21836184...
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moderate amounts of fructose and lactose, particularly if they have lactase persistence. A low-FODMAP diet consists of the global restriction of all fermentable...
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Thomas B.; Ghori, Jilur (2007-01-01). "Convergent adaptation of human lactase persistence in Africa and Europe". Nature Genetics. 39 (1): 31–40. doi:10.1038/ng1946...
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the selection pressure that led to the spread of alleles for adult lactase persistence. Analyses of the human genome have identified many hundreds of genes...
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Thomas B.; Ghori, Jilur (2007-01-01). "Convergent adaptation of human lactase persistence in Africa and Europe". Nature Genetics. 39 (1): 31–40. doi:10.1038/ng1946...
18 KB (2,163 words) - 23:14, 25 May 2025