of the body. The frequency of mutations in mouse somatic tissue (brain, liver, Sertoli cells) was compared to the mutation frequency in male germline...

Mutation frequency and mutation rates are highly correlated to each other. Mutation frequencies test are cost effective in laboratories however; these...

cell populations, cells with mutations will increase or decrease in frequency according to the effects of the mutations on the ability of the cell to...

In genetics, the mutation rate is the frequency of new mutations in a single gene, nucleotide sequence, or organism over time. Mutation rates are not constant...

are differences in the types of mutation seen in the germ and in the soma. There is variation in mutation frequency between different somatic tissues...

Whole genome sequencing has established the mutation frequency for whole human genomes. The mutation frequency in the whole genome between generations for...

cells, that is 5 to 10-fold lower than the mutation frequency in somatic cells Thus low mutation frequency is a feature of germline cells in both sexes...

higher exome mutation frequency) the total number of DNA sequence mutations is about 80,000. This compares to the very low mutation frequency of about 70...

Mutation Frequency Decline (mfd) is the gene which encodes the protein Mfd (also known as Transcription Repair Coupling Factor, TRCF). Mfd functions in...

A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number...

deleterious (very small s {\displaystyle s} ) and the mutation rate is not very high, the equilibrium frequency of the deleterious allele will be small. In a...

Furthermore, mutation frequency can vary between cancer types: in germline cells, mutation rates occur at approximately 0.023 mutations per megabase,...

cells, mutant cells will increase or decrease in frequency according to the effects of the mutation on the ability of the cell to survive and reproduce...

cell types from the same individual. Female germ cells also show a mutation frequency that is lower than that in corresponding somatic cells and similar...

Sertoli cells have a higher mutation frequency than spermatogenic cells. Compared to spermatocytes, the mutation frequency is about 5 to 10-fold higher...

in 1946, asserted in his Nobel lecture, The Production of Mutation, that mutation frequency is "directly and simply proportional to the dose of irradiation...

transversion mutations. Such mutations occur throughout the mouse chromosomes as well as during different stages of gametogenesis. The mutation frequencies for...

the accumulation of mutation load, culminating in extinction via mutational meltdown. The accumulation of deleterious mutations in humans has been of...

chromosome and causing mutation. Transposon mutagenesis is much more effective than chemical mutagenesis, with a higher mutation frequency and a lower chance...

the mutation frequencies of cells at the different stages, including pachytene spermatocytes, are 5 to 10-fold lower than the mutation frequencies in somatic...

spontaneous mutation rate (mutator phenotype). In comparison to other cancer types, MMR-deficient (MSI) cancer has a very high frequency of mutations, close...

In genetics, a nonsense mutation is a point mutation in a sequence of DNA that results in a nonsense codon, or a premature stop codon in the transcribed...

the ebony mutation to a wild-type population. The ebony allele persisted through many generations of flies in the study, at genotype frequencies that varied...

Oum, Muna; Del Longo, Alessandra; et al. (January 2014). "SLC45A2 mutation frequency in Oculocutaneous Albinism Italian patients doesn't differ from other...

colors. Nonsense mutations that created this premature stop codon were later called opal mutations or umber mutations. Nonsense mutations are changes in...

stages of development in the mouse have a frequency of mutation that is 5 to 10-fold lower than the mutation frequency in somatic cells. In Drosophila, the...

mechanism), gene flow, and mutation combine to change allele frequencies across generations. Genetic drift causes changes in allele frequency from random sampling...

allele frequencies too. Selective sweeps happen when newly appeared (and hence still rare) mutations are advantageous and increase in frequency. Neutral...

Somatic evolution is the accumulation of mutations and epimutations in somatic cells (the cells of a body, as opposed to germ plasm and stem cells) during...

endometrial endometrioid carcinomas (28%). This difference in CTNNB1 mutation frequency may be reflective of the distinct tumoral microenvironments; the epithelial...