The nuclear receptor coactivator 1 (NCOA1), also called steroid receptor coactivator-1 (SRC-1), is a transcriptional coregulatory protein that contains...
15 KB (1,699 words) - 20:28, 22 November 2023
The nuclear receptor coactivator 3 also known as NCOA3 is a protein that, in humans, is encoded by the NCOA3 gene. NCOA3 is also frequently called 'amplified...
21 KB (2,383 words) - 15:17, 11 October 2023
The nuclear receptor coactivator 2 also known as NCoA-2 is a protein that in humans is encoded by the NCOA2 gene. NCoA-2 is also frequently called glucocorticoid...
19 KB (2,166 words) - 15:30, 5 March 2024
In the field of molecular biology, nuclear receptors are a class of proteins responsible for sensing steroids, thyroid hormones, vitamins, and certain...
74 KB (6,675 words) - 05:46, 31 May 2024
The nuclear receptor co-repressor 1 also known as thyroid-hormone- and retinoic-acid-receptor-associated co-repressor 1 (TRAC-1) is a protein that in...
23 KB (2,678 words) - 09:26, 16 May 2024
coactivator) CRTC1 (CRTC1) CRTC2 (CRTC2) CRTC3 (CRTC3) CARM1 (coactivator-associated arginine methyltransferase 1) CARM1 Nuclear receptor coactivator...
9 KB (1,039 words) - 04:15, 25 March 2024
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by...
87 KB (9,673 words) - 02:09, 31 May 2024
Retinoid X receptor alpha (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear receptor that in humans is encoded...
25 KB (2,892 words) - 21:07, 15 November 2023
"The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha)"....
11 KB (1,175 words) - 13:05, 3 December 2023
receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear...
60 KB (6,357 words) - 21:20, 29 March 2024
Thyroid hormone receptor beta (TR-beta) also known as nuclear receptor subfamily 1, group A, member 2 (NR1A2), is a nuclear receptor protein that in humans...
14 KB (1,742 words) - 05:20, 3 December 2023
ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic...
4 KB (569 words) - 02:32, 19 December 2023
receptors EP300 targets many transcription factors KAT5 targets many nuclear receptors KDM1A targets androgen receptors Steroid receptor coactivator (SRC)...
18 KB (1,698 words) - 10:42, 3 December 2023
proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear receptor subfamily 1, group...
20 KB (2,137 words) - 06:53, 4 January 2024
collectively termed coregulators and including coactivators and corepressors. The study of nuclear receptors owed a debt to decades of historical endocrinology...
26 KB (3,070 words) - 06:34, 27 December 2023
The nuclear receptor 4A1 (NR4A1 for "nuclear receptor subfamily 4 group A member 1") also known as Nur77, TR3, and NGFI-B is a protein that in humans is...
21 KB (2,530 words) - 02:53, 28 March 2024
classes of ER exist: nuclear estrogen receptors (ERα and ERβ), which are members of the nuclear receptor family of intracellular receptors, and membrane estrogen...
35 KB (3,818 words) - 15:00, 9 May 2024
the receptor/DNA complex. Coactivator proteins are recruited, forming a DNA/TR/coactivator complex. One coactivator recruited to the site is nuclear receptor...
21 KB (2,286 words) - 14:48, 21 March 2024
PPARGC1A (redirect from PPARγ coactivator 1-α)
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is...
28 KB (3,324 words) - 06:25, 3 June 2024
Proline-rich nuclear receptor coactivator 1 is a protein that, in humans, is encoded by the PNRC1 gene. PNRC1 functions as a coactivator for several nuclear receptors...
4 KB (475 words) - 23:30, 3 March 2023
acid receptor (BAR), also known as farnesoid X receptor (FXR) or NR1H4 (nuclear receptor subfamily 1, group H, member 4), is a nuclear receptor that is...
17 KB (1,979 words) - 22:14, 13 March 2024
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is...
14 KB (1,628 words) - 10:26, 5 January 2024
estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen". Cell. 95 (7): 927–37. doi:10.1016/S0092-8674(00)81717-1. PMID 9875847...
56 KB (6,397 words) - 06:15, 13 January 2024
The glucocorticoid receptor (GR or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other...
37 KB (4,034 words) - 20:56, 15 April 2024
upstream of target genes in complex with a number of coactivators such as nuclear receptor coactivator 1 and CREB binding protein, this causes upregulation...
20 KB (2,133 words) - 22:39, 27 April 2024
Thyroid hormone receptor alpha (TR-alpha) also known as nuclear receptor subfamily 1, group A, member 1 (NR1A1), is a nuclear receptor protein that in...
14 KB (1,730 words) - 03:58, 8 September 2023
Selective androgen receptor modulators (SARMs) are a class of drugs that selectively activate the androgen receptor in specific tissues, promoting muscle...
74 KB (6,753 words) - 23:47, 22 April 2024
The retinoid X receptor (RXR) is a type of nuclear receptor that is activated by 9-cis retinoic acid, which is discussed controversially to be of endogenous...
6 KB (542 words) - 21:06, 15 November 2023
electrospray mass spectrometry: cyclopeptidic inhibitors of the nuclear receptor coactivator 1-STAT6". J. Am. Soc. Mass Spectrom. 20 (2): 303–11. doi:10.1016/j...
45 KB (5,340 words) - 04:10, 1 April 2024
PPARG coactivator 1 alpha is a protein that in humans is encoded by the PPARGC1A gene. The protein encoded by this gene is a transcriptional coactivator that...
5 KB (637 words) - 08:17, 11 March 2024