Programmed cell death protein 1 (PD-1), (CD279 cluster of differentiation 279). PD-1 is a protein encoded in humans by the PDCD1 gene. PD-1 is a cell...
42 KB (5,240 words) - 04:42, 30 June 2025
PDCD1LG2 (redirect from Programmed cell death 1 ligand 2)
Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has also been designated...
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the programmed death-ligand 1 (PD-L1) with its receptor, programmed cell death protein 1 (PD-1). The interaction of these cell surface proteins is involved...
35 KB (3,431 words) - 06:50, 30 June 2025
Programmed cell death (PCD) sometimes referred to as cell, or cellular suicide is the death of a cell as a result of events inside of a cell, such as apoptosis...
57 KB (6,843 words) - 21:58, 9 June 2025
pathways of programmed cell death have been discovered. Called "non-apoptotic programmed cell-death" (or "caspase-independent programmed cell-death"), these...
21 KB (2,738 words) - 17:32, 16 June 2025
receptors including programmed cell death protein 1 (PD1), CTLA-4, T cell membrane protein-3 (TIM3), and lymphocyte activation gene 3 protein (LAG3). Soluble...
73 KB (9,255 words) - 21:44, 2 July 2025
or Medicine and is best known for his identification of programmed cell death protein 1 (PD-1). He is also known for his molecular identification of cytokines...
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anti-PD-1 immune checkpoint inhibitor that is being investigated for hepatocellular carcinoma and Hodgkin lymphoma. PD-1 is programmed cell death protein 1....
4 KB (136 words) - 03:50, 12 March 2025
PD-L1 (redirect from Programmed cell death 1 ligand 1)
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded...
29 KB (3,320 words) - 08:04, 30 June 2025
nasopharyngeal carcinoma. Toripalimab is a recombinant humanized programmed cell death protein 1 (PD-1) monoclonal antibody that acts as a checkpoint inhibitor...
9 KB (640 words) - 21:57, 7 March 2025
antibody used for the treatment of cancer. It targets the programmed cell death protein 1 (PD-1) receptor. Penpulimab was approved for medical use in China...
12 KB (1,015 words) - 21:50, 29 May 2025
medication used for the treatment of Merkel cell carcinoma. Retifanlimab is a programmed death receptor-1 (PD-1)–blocking monoclonal antibody. It was approved...
11 KB (764 words) - 22:04, 29 May 2025
It is a fully human IgG4 monoclonal antibody that binds to programmed cell death protein 1. It was jointly developed by Innovent Biologics and Eli Lilly...
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protective mechanism of cancer cells, allowing the immune system to destroy them. It targets the programmed cell death protein 1 (PD-1) receptor of lymphocytes...
85 KB (7,877 words) - 03:24, 14 June 2025
engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1). The most common side effects when used on its own...
45 KB (4,281 words) - 02:23, 19 June 2025
Immunotherapy (redirect from Cell-based immunotherapy)
of anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed cell death protein 1 (PD-1) antibodies for human use has already resulted...
56 KB (6,123 words) - 10:05, 28 June 2025
fucosylation and fucosylated HLA-DRB1 are associated with anti-programmed cell death protein 1 (PD1) responder status, pointing to the potential use of melanoma...
5 KB (591 words) - 19:14, 25 March 2024
Necroptosis (redirect from Programmed necrosis)
contrast to orderly, programmed cell death via apoptosis. The discovery of necroptosis showed that cells can execute necrosis in a programmed fashion and that...
14 KB (1,667 words) - 09:21, 5 November 2024
Cancer immunotherapy (redirect from Cell transfer therapy)
of programmed cell death 1 ligand 1 or programmed cell death 1 ligand 2 (PD-L1 or PD-L2), a protein expressed by cancer cells, with PD-1, a protein found...
101 KB (13,421 words) - 02:46, 26 June 2025
B7-1, B7-2 and other members of the B7 gene family as well as of CD28 and CTLA-4 in T cell activation and of PD-L1 / PD-1 (programmed cell death protein...
3 KB (287 words) - 08:21, 22 October 2024
Immunoglobulin V-set domain (category Protein domains)
tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1). Immunoglobulin V-set, subgroup InterPro: IPR003596 T-cell surface...
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of cancer. Nivolumab/hyaluronidase contains nivolumab, a programmed death receptor-1 (PD-1)-blocking monoclonal antibody; and hyaluronidase, an endoglycosidase...
7 KB (363 words) - 18:56, 28 June 2025
prevents tumor proliferation and angiogenesis by inhibiting programmed cell death protein 1 and vascular endothelial growth factor A, respectively. Ivonescimab...
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IgG4 monoclonal antibody directed against the programmed cell death protein 1 located on the surface of cells) in combination with two chemotherapy drugs...
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refer to: Prussian S 3 a 19th-century steam locomotive PD-1 the Programmed cell death protein 1 receptor This disambiguation page lists articles associated...
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Inhibitor of apoptosis (redirect from Programmed cell death inhibitor)
proteins that mainly act on the intrinsic pathway that block programmed cell death, which can frequently lead to cancer or other effects for the cell...
13 KB (1,569 words) - 04:02, 12 January 2025
Th cells contain and release cytokines to aid other immune cells. Cytokines are small protein mediators that alter the behavior of target cells that...
54 KB (6,618 words) - 15:58, 30 April 2025
of squamous cell skin cancer. Cemiplimab belongs to a class of drugs that binds to the programmed death receptor-1 (PD-1), blocking the PD-1/PD-L1 pathway...
13 KB (1,068 words) - 20:18, 29 May 2025
Death-associated protein 6 also known as Daxx is a protein that in humans is encoded by the DAXX gene. Daxx, a Death domain-associated protein, was first...
11 KB (1,528 words) - 20:53, 21 December 2023
Apoptosis (redirect from Caspase-mediated cell death)
'falling off') is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast...
94 KB (10,857 words) - 03:28, 2 June 2025