• Thumbnail for Programmed cell death protein 1
    Programmed cell death protein 1 (PD-1), (CD279 cluster of differentiation 279). PD-1 is a protein encoded in humans by the PDCD1 gene. PD-1 is a cell...
    42 KB (5,240 words) - 04:42, 30 June 2025
  • Thumbnail for PDCD1LG2
    Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has also been designated...
    19 KB (2,037 words) - 23:10, 23 March 2025
  • Thumbnail for PD-1 and PD-L1 inhibitors
    the programmed death-ligand 1 (PD-L1) with its receptor, programmed cell death protein 1 (PD-1). The interaction of these cell surface proteins is involved...
    35 KB (3,431 words) - 06:50, 30 June 2025
  • Programmed cell death (PCD) sometimes referred to as cell, or cellular suicide is the death of a cell as a result of events inside of a cell, such as apoptosis...
    57 KB (6,843 words) - 21:58, 9 June 2025
  • Thumbnail for Cell death
    pathways of programmed cell death have been discovered. Called "non-apoptotic programmed cell-death" (or "caspase-independent programmed cell-death"), these...
    21 KB (2,738 words) - 17:32, 16 June 2025
  • Thumbnail for T cell
    receptors including programmed cell death protein 1 (PD1), CTLA-4, T cell membrane protein-3 (TIM3), and lymphocyte activation gene 3 protein (LAG3). Soluble...
    73 KB (9,255 words) - 21:44, 2 July 2025
  • Thumbnail for Tasuku Honjo
    or Medicine and is best known for his identification of programmed cell death protein 1 (PD-1). He is also known for his molecular identification of cytokines...
    15 KB (1,542 words) - 23:26, 23 June 2025
  • anti-PD-1 immune checkpoint inhibitor that is being investigated for hepatocellular carcinoma and Hodgkin lymphoma. PD-1 is programmed cell death protein 1....
    4 KB (136 words) - 03:50, 12 March 2025
  • Thumbnail for PD-L1
    Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded...
    29 KB (3,320 words) - 08:04, 30 June 2025
  • nasopharyngeal carcinoma. Toripalimab is a recombinant humanized programmed cell death protein 1 (PD-1) monoclonal antibody that acts as a checkpoint inhibitor...
    9 KB (640 words) - 21:57, 7 March 2025
  • antibody used for the treatment of cancer. It targets the programmed cell death protein 1 (PD-1) receptor. Penpulimab was approved for medical use in China...
    12 KB (1,015 words) - 21:50, 29 May 2025
  • medication used for the treatment of Merkel cell carcinoma. Retifanlimab is a programmed death receptor-1 (PD-1)–blocking monoclonal antibody. It was approved...
    11 KB (764 words) - 22:04, 29 May 2025
  • It is a fully human IgG4 monoclonal antibody that binds to programmed cell death protein 1. It was jointly developed by Innovent Biologics and Eli Lilly...
    6 KB (385 words) - 19:27, 29 June 2025
  • Thumbnail for Pembrolizumab
    protective mechanism of cancer cells, allowing the immune system to destroy them. It targets the programmed cell death protein 1 (PD-1) receptor of lymphocytes...
    85 KB (7,877 words) - 03:24, 14 June 2025
  • Thumbnail for Atezolizumab
    engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1). The most common side effects when used on its own...
    45 KB (4,281 words) - 02:23, 19 June 2025
  • of anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed cell death protein 1 (PD-1) antibodies for human use has already resulted...
    56 KB (6,123 words) - 10:05, 28 June 2025
  • fucosylation and fucosylated HLA-DRB1 are associated with anti-programmed cell death protein 1 (PD1) responder status, pointing to the potential use of melanoma...
    5 KB (591 words) - 19:14, 25 March 2024
  • Thumbnail for Necroptosis
    contrast to orderly, programmed cell death via apoptosis. The discovery of necroptosis showed that cells can execute necrosis in a programmed fashion and that...
    14 KB (1,667 words) - 09:21, 5 November 2024
  • Thumbnail for Cancer immunotherapy
    of programmed cell death 1 ligand 1 or programmed cell death 1 ligand 2 (PD-L1 or PD-L2), a protein expressed by cancer cells, with PD-1, a protein found...
    101 KB (13,421 words) - 02:46, 26 June 2025
  • B7-1, B7-2 and other members of the B7 gene family as well as of CD28 and CTLA-4 in T cell activation and of PD-L1 / PD-1 (programmed cell death protein...
    3 KB (287 words) - 08:21, 22 October 2024
  • Thumbnail for Immunoglobulin V-set domain
    Immunoglobulin V-set domain (category Protein domains)
    tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1). Immunoglobulin V-set, subgroup InterPro: IPR003596 T-cell surface...
    6 KB (371 words) - 13:34, 28 February 2025
  • of cancer. Nivolumab/hyaluronidase contains nivolumab, a programmed death receptor-1 (PD-1)-blocking monoclonal antibody; and hyaluronidase, an endoglycosidase...
    7 KB (363 words) - 18:56, 28 June 2025
  • prevents tumor proliferation and angiogenesis by inhibiting programmed cell death protein 1 and vascular endothelial growth factor A, respectively. Ivonescimab...
    4 KB (345 words) - 14:48, 9 March 2025
  • Thumbnail for Liposarcoma
    IgG4 monoclonal antibody directed against the programmed cell death protein 1 located on the surface of cells) in combination with two chemotherapy drugs...
    72 KB (8,487 words) - 17:55, 22 June 2025
  • refer to: Prussian S 3 a 19th-century steam locomotive PD-1 the Programmed cell death protein 1 receptor This disambiguation page lists articles associated...
    162 bytes (58 words) - 17:52, 29 December 2019
  • proteins that mainly act on the intrinsic pathway that block programmed cell death, which can frequently lead to cancer or other effects for the cell...
    13 KB (1,569 words) - 04:02, 12 January 2025
  • Thumbnail for T helper cell
    Th cells contain and release cytokines to aid other immune cells. Cytokines are small protein mediators that alter the behavior of target cells that...
    54 KB (6,618 words) - 15:58, 30 April 2025
  • of squamous cell skin cancer. Cemiplimab belongs to a class of drugs that binds to the programmed death receptor-1 (PD-1), blocking the PD-1/PD-L1 pathway...
    13 KB (1,068 words) - 20:18, 29 May 2025
  • Thumbnail for Death-associated protein 6
    Death-associated protein 6 also known as Daxx is a protein that in humans is encoded by the DAXX gene. Daxx, a Death domain-associated protein, was first...
    11 KB (1,528 words) - 20:53, 21 December 2023
  • Thumbnail for Apoptosis
     'falling off') is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast...
    94 KB (10,857 words) - 03:28, 2 June 2025