• RIG-I-like receptors (retinoic acid-inducible gene-I-like receptors, RLRs) are a type of intracellular pattern recognition receptor involved in the recognition...
    25 KB (3,011 words) - 17:07, 24 May 2024
  • Thumbnail for RIG-I
    RIG-I (retinoic acid-inducible gene I) is a cytosolic pattern recognition receptor (PRR) that can mediate induction of a type-I interferon (IFN1) response...
    24 KB (2,958 words) - 03:55, 10 February 2025
  • Thumbnail for NOD-like receptor
    Pseudomonas aeruginosa, Listeria monocytogenes. Toll-like receptor Inflammasome RIG-I-like receptor Mahla, Ranjeet (2013). "Sweeten PAMPs: Role of Sugar...
    14 KB (1,532 words) - 23:00, 21 November 2023
  • include toll-like receptors (TLRs) and C-type lectin receptors (CLRs). Cytoplasmic PRRs include NOD-like receptors (NLRs) and RIG-I-like receptors (RLRs)....
    49 KB (5,846 words) - 06:49, 2 June 2025
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    LGP2 (category RIG-I-like receptors)
    RNA helicase DHX58 also known as RIG-I-like receptor 3 (RLR-3) or RIG-I-like receptor LGP2 (RLR) is a RIG-I-like receptor dsRNA helicase enzyme that in humans...
    9 KB (1,101 words) - 12:27, 13 August 2023
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    MDA5 (category RIG-I-like receptors)
    protein 5) is a RIG-I-like receptor dsRNA helicase enzyme that is encoded by the IFIH1 gene in humans. MDA5 is part of the RIG-I-like receptor (RLR) family...
    19 KB (2,222 words) - 15:02, 25 May 2025
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    prestigious medical prize". The Star. NOD-like receptor Immunologic adjuvant RIG-I-like receptor Toll-Like+Receptors at the U.S. National Library of Medicine...
    61 KB (6,771 words) - 19:25, 22 May 2025
  • immunoglobulin-like receptors Major histocompatibility complex (MHC) NOD-like receptors Pattern recognition receptor Toll-like receptors RIG-I like receptors Dynein...
    3 KB (275 words) - 04:29, 5 August 2024
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    oligomerization domain (NOD)-like receptors, retinoic acid inducible gene-I (RIG-I)-like receptors and C-type lectin-like receptors (CLRs). They recognize alarmins...
    11 KB (1,153 words) - 15:53, 1 September 2024
  • viruses. The PRRs that sense viruses are TLRs, RLRs (Rig-I-like receptors), CLRs (C-type lectine receptors), and inflammasomes/DNA sensors. CLRs are mainly...
    18 KB (2,144 words) - 05:35, 26 May 2025
  • Fujita T (2008). "Structural mechanism of RNA recognition by the RIG-I-like receptors". Immunity. 29 (2): 178–181. doi:10.1016/j.immuni.2008.07.009. PMID 18701081...
    34 KB (4,131 words) - 09:48, 4 June 2025
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    the toll-like receptors, the C-type lectin receptors, the NOD-like receptors, and the RIG-I-like receptors. Invariably, the association of a PAMP and...
    125 KB (13,631 words) - 15:36, 22 May 2025
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    I interferons which signal other cells to increase their antiviral defenses. Double-stranded RNA is also recognised by the cytoplasmic receptors RIG-I...
    9 KB (1,027 words) - 06:24, 13 September 2024
  • Thumbnail for Ubiquitin
    acid-inducible gene I (RIG-I) protein is a primary immune system sensor for viral and other invasive RNA in human cells. The RIG-I-like receptor (RLR) immune...
    101 KB (11,338 words) - 19:50, 22 April 2025
  • like receptors (TLRs), nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) and retinoic acid-inducible gene (RIG)-I-like receptors (RLRs)...
    16 KB (1,725 words) - 16:11, 26 May 2025
  • Lloyd Racing, a defunct British auto racing team RIG-I-like receptor, a family of intracellular receptors Ruislip Lido Railway, a miniature railway in England...
    502 bytes (97 words) - 19:21, 4 May 2021
  • NLRP14 NLRX NLRX1 RIG-I-like receptors (RLRs) - Intracellular sensors of viral replication by direct interaction with dsRNA RIG-I MDA5 LGP2 Secreted...
    38 KB (2,656 words) - 20:26, 6 November 2024
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    Ebola vaccine (category Articles without InChI source)
    developed, and showed positive results in the activation of the RIG-I-like receptor signaling. Non-human primates were challenged with different doses...
    67 KB (6,259 words) - 20:40, 29 May 2025
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    mitochondrial transcription, can activate viral sensing pathways through RIG-I-like receptors. Additionally, the N-formylation of mitochondrial proteins, similar...
    169 KB (18,655 words) - 17:45, 22 May 2025
  • toll-like receptors (TLRs) and the RIG-I-like receptor family. TLRs are localized in the endosomal compartment of cells, such as DCs and macrophages. RIG-I-like...
    83 KB (9,543 words) - 01:52, 1 June 2025
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    receptor to initiate type I interferon (IFN-I) expression and viral clearance. Interestingly, ATG5-ATG12/ATG16L1 complex negatively regulates RIG-I-like...
    16 KB (1,731 words) - 06:41, 27 September 2024
  • Thumbnail for Mitochondrial antiviral-signaling protein
    transmembrane toll-like receptor 3 (TLR3) or by one of two cytosolic proteins, retinoic acid-inducible gene I (RIG-I)-like receptors and melanoma...
    16 KB (1,931 words) - 04:40, 20 May 2025
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    also essential for the association of RIG-I-like receptors (RIG-I or MDA5) to VISA. The bridging of these receptors to VISA is an important signaling event...
    7 KB (837 words) - 07:50, 10 March 2024
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    degradation. SKIV2L has been shown to be a negative regulator of the Rig-I like receptors (RLRs) that detect RNA. The authors found that the cytosolic RNA...
    26 KB (3,218 words) - 05:55, 10 March 2024
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    the RNA mimetic poly I:C and Sendai virus. It is therefore submitted that MUL1 is a novel regulator of the RIG-I-like receptor-dependent antiviral response...
    11 KB (1,339 words) - 21:10, 5 April 2024
  • researched inflammatory pathways stimulated by Toll-like Receptors, cGAS-STING, RIG-I like Receptors and inflammasomes. Kagan's studies have led to a map...
    29 KB (3,468 words) - 20:03, 12 February 2024
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    Interleukin-1, signaling. Following activation of viral RNA sensors, such as RIG-I-like receptors, associates with DDX3X and phosphorylates interferon regulatory factors...
    11 KB (1,381 words) - 08:33, 30 November 2023
  • manner, protecting it from nucleases and host pattern recognition receptors such as RIG-I and MDA5. RNP Assembly: NP-RNA complexes serve as templates for...
    12 KB (1,314 words) - 04:40, 20 May 2025
  • Virus Nsp4 Cleaves VISA to Impair Antiviral Responses Mediated by RIG-I-like Receptors". Scientific Reports. 6 (1): 28497. Bibcode:2016NatSR...628497H....
    47 KB (5,032 words) - 12:20, 22 May 2025
  • Thumbnail for Interferon-alpha/beta receptor
    interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human type I IFNs...
    24 KB (2,617 words) - 19:43, 7 August 2022