Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display...

Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders that are typically inherited. The most common...

with the sickle cell trait and about 100 million of those are in sub-Saharan Africa. There is also a higher prevalence of sickle cell trait in areas that...

hemoglobin from healthy individuals and those with sickle-cell anemia, with those with sickle cell trait having a mixture of the two types. The paper suggests...

individuals with this type of cancer have sickle cell trait or rarely sickle cell disease, suggesting that the sickle cell trait may be a risk factor for this type...

needed] Sickle-cell disease: 53  Sanfilippo syndrome[citation needed] Tay–Sachs disease: 53  Wet (dominant) or dry (recessive) earwax Most traits (including...

in common with those who have sickle-cell trait, have some protection against malaria, explaining why sickle-cell trait and thalassemia are historically...

Steelers in Super Bowl XLIII, and made a Pro Bowl in 2011. Clark has a sickle cell trait condition which made it dangerous for him to play at high altitudes...

"sickle cell crisis" is a sickle cell disease—not the same as sickle cell trait. By itself, the sickle cell trait is not harmful. People with sickle cell...

samples he collected that there was an unusually high occurrence of sickle-cell trait in its less harmful (heterozygous) condition. He conceived the idea...

relatively benign and like sickle cell trait to being similar to sickle cell disease. Patients with sickle cell-beta thalassemia may present with painful...

provides the fitness benefit of malaria resistance to heterozygotes as sickle cell trait, while homozygotes have significantly lowered life expectancy—what...

However, these heterozygote individuals, known as carriers of the sickle cell trait, may suffer problems from time to time. The heterozygote is resistant...

by the sickle cell trait". PLOS Medicine. 2 (5): e128. doi:10.1371/journal.pmed.0020128. PMC 1140945. PMID 15916466. Hebbel RP (2003). "Sickle hemoglobin...

Brody, Lawrence C. (2010-09-09). "Screening student athletes for sickle cell trait--a social and clinical experiment". The New England Journal of Medicine...

16, 2025. Portero, Lou (January 20, 2023). "Freshman Dies From Acute Sickle Cell Crisis". Urban Health Today. Retrieved February 16, 2025. "North Carolina...

accepted into training. During the training, he was diagnosed with sickle cell trait and was removed from training temporarily. Goggins instead participated...

nose width, in favor of examining blood factors, the presence of the sickle cell trait, lactose intolerance in adults, and other genotype expressions. Excoffier...

Smokey? Because you are fast?’ But no.” Brown was diagnosed with sickle cell trait in 2016 after suffering from soreness in his hamstrings. He insisted...

sickle cell anaemia. Often, the advantages and disadvantages conveyed are rather complicated, because more than one gene may influence a given trait or...

of sickle cell trait on malaria immunity illustrates some evolutionary trade-offs that have occurred because of endemic malaria. Sickle cell trait causes...

previous exposure or vaccination, or through genetic immunity, such as sickle cell trait conferring resistance to malaria. Other exceptions to Koch's postulates...

the sickle cell disease to be less severe. In essence the HbF inhibits polymerization of HbS. A similar mechanism occurs with persons who have sickle cell...

it may be a symptom of kidney disease, such as IgA nephropathy or Sickle cell trait, which should be monitored by a doctor. The American Urological Association...

compared to their mother's cells, which carried the disease trait. Later, it was noted that patients with sickle cell trait as well as hereditary persistence...

causing sickle cell trait with one adult gene and one sickle cell disease gene Hemoglobin SC disease – A compound heterozygous form with one sickle gene...

associated trait or disease. In the combined case of sickle cell anemia and malaria, individuals with one normal allele and one sickle cell allele, (heterozygous...

excrete water based on the body's hydration status. Sickle-cell trait, the heterozygous form of sickle-cell disease, presents with a normal hematological picture...

blood cells (e.g., anemia of chronic disease, aplastic anemia); an increased production of HbS as seen in sickle cell disease (not sickle cell trait); an...

stating that Neely died from a combination of factors, including his sickle cell trait, a schizophrenic episode, struggling with Penny's restraint, and intoxication...