• The sodium-calcium exchanger (often denoted Na+/Ca2+ exchanger, exchange protein, or NCX) is an antiporter membrane protein that removes calcium from cells...
    20 KB (2,223 words) - 11:43, 21 March 2025
  • Thumbnail for Sodium/potassium/calcium exchanger 5
    Sodium/potassium/calcium exchanger 5 (NCKX5), also known as solute carrier family 24 member 5 (SLC24A5), is a protein that in humans is encoded by the...
    19 KB (1,993 words) - 04:56, 29 August 2024
  • Thumbnail for Antiporter
    Na+/Ca2+ exchanger, found in the plasma membrane of many cells, moves three sodium ions in one direction, and one calcium ion in the other. As with sodium in...
    60 KB (7,840 words) - 00:16, 11 February 2025
  • Thumbnail for Sodium/potassium/calcium exchanger 4
    Sodium/potassium/calcium exchanger 4 also known as solute carrier family 24 member 4 is a protein that in humans is encoded by the SLC24A4 gene. Mutations...
    2 KB (227 words) - 19:54, 3 March 2023
  • Potassium-dependent sodium-calcium exchanger also known as solute carrier family 24 (SLC24) is a type of sodium-calcium exchanger that requires potassium...
    3 KB (90 words) - 00:21, 5 October 2020
  • cause of muscle cramps. The plasma membrane Ca2+ ATPase and the sodium-calcium exchanger are together the main regulators of cytoplasmic Ca2+ concentrations...
    6 KB (559 words) - 17:37, 9 December 2024
  • Thumbnail for Plasma membrane Ca2+ ATPase
    cells to employ ion pumps to remove the Ca2+. The PMCA and the sodium calcium exchanger (NCX) are together the main regulators of intracellular Ca2+ concentrations...
    17 KB (1,860 words) - 16:54, 13 August 2024
  • Thumbnail for Cardiac action potential
    out of the cell and two K+ into the cell. Another example is the sodium-calcium exchanger which removes one Ca2+ from the cell for three Na+ into the cell...
    46 KB (5,430 words) - 18:10, 24 April 2024
  • Thumbnail for Sodium–potassium pump
    cardiotonic steroid inhibition. Sodium-calcium exchanger Thyroid hormone V-ATPase Gagnon KB, Delpire E (2021). "Sodium Transporters in Human Health and...
    38 KB (4,367 words) - 07:33, 1 March 2025
  • Thumbnail for Cotransporter
    example of an antiporter is the sodium-calcium exchanger. The sodium-calcium exchanger functions to remove excess calcium from the cytoplasmic space into...
    22 KB (2,289 words) - 23:55, 8 February 2025
  • Thumbnail for Calcium ATPase
    cell to employ ion pumps to remove the Ca2+. The PMCA and the sodium calcium exchanger (NCX) are together the main regulators of intracellular Ca2+ concentrations...
    6 KB (572 words) - 19:54, 5 April 2025
  • L-type calcium channel has increased activity. The sodium-calcium exchanger (which allows 3 Na+ to flow down its electrochemical gradient in exchange for...
    6 KB (682 words) - 05:32, 27 July 2024
  • Thumbnail for Calcium in biology
    of intracellular calcium are regulated by transport proteins that remove it from the cell. For example, the sodium-calcium exchanger uses energy from...
    39 KB (4,236 words) - 04:28, 16 February 2025
  • Thumbnail for Muscle contraction
    begin. Calcium is also ejected from the cell mainly by the sodium-calcium exchanger (NCX) and, to a lesser extent, a plasma membrane calcium ATPase....
    62 KB (7,395 words) - 01:35, 14 April 2025
  • Thumbnail for Membrane potential
    the sodium-calcium exchanger. This pump operates in a conceptually similar way to the sodium-potassium pump, except that in each cycle it exchanges three...
    65 KB (8,286 words) - 00:30, 22 April 2025
  • Thumbnail for T-tubule
    such as the sodium-calcium exchanger and the sarcolemmal ATPase are located mainly in the T-tubule membrane. The sodium-calcium exchanger passively removes...
    25 KB (3,239 words) - 22:26, 16 March 2025
  • 30 per second versus 2000 per second by the exchanger. The exchanger comes into service when the calcium concentration rises steeply or "spikes" and enables...
    32 KB (3,832 words) - 18:06, 5 March 2025
  • Calcium-induced calcium release (CICR) describes a biological process whereby calcium is able to activate calcium release from intracellular Ca2+ stores...
    4 KB (423 words) - 09:37, 2 November 2022
  • Thumbnail for Ion exchange
    batteries. Ion exchange can also be used to remove hardness from water by exchanging calcium and magnesium ions for sodium ions in an ion-exchange column. Liquid-phase...
    20 KB (2,212 words) - 15:43, 19 January 2025
  • Thumbnail for Calcium signaling
    Calcium signaling is the use of calcium ions (Ca2+) to communicate and drive intracellular processes often as a step in signal transduction. Ca2+ is important...
    21 KB (2,484 words) - 19:48, 13 April 2025
  • Thumbnail for Long QT syndrome
    conditions, reactivation of these currents, facilitated by the sodium-calcium exchanger, can cause further depolarisation of the cell. The early afterdepolarisations...
    64 KB (6,655 words) - 00:08, 13 May 2025
  • Thumbnail for Caveolin 3
    amount of cellular damage. Caveolin-3 associates with the cardiac sodium-calcium exchanger (NCX) in caveolae of cardiac myocytes. This association occurs...
    21 KB (2,508 words) - 16:21, 15 January 2025
  • Thumbnail for Sodium carbonate
    usually contains calcium or magnesium ions. Sodium carbonate is used for removing these ions and replacing them with sodium ions. Sodium carbonate is a...
    32 KB (3,101 words) - 22:55, 16 May 2025
  • S2CID 11670040. Quednau BD, Nicoll DA, Philipson KD (February 2004). "The sodium/calcium exchanger family-SLC8". Pflügers Archiv. 447 (5): 543–548. doi:10.1007/s00424-003-1065-4...
    35 KB (3,408 words) - 02:42, 30 November 2023
  • back into the SR, the Sarcolemmal sodium-calcium exchanger, which pumps one Ca2+ out of the cell, in exchange for 3 sodium ions being pumped into the cell...
    13 KB (1,425 words) - 00:32, 18 January 2025
  • concentration of sodium, which in turn increases intracellular calcium by passively increasing the action of the sodium-calcium exchanger in the sarcolemma...
    44 KB (4,524 words) - 20:52, 2 January 2025
  • cell death. Calcium is balanced through the MCU in conjunction with the sodium-calcium exchanger. The MCU has a very low affinity for calcium, so the cytosolic...
    7 KB (818 words) - 16:59, 7 May 2025
  • Thumbnail for Ankyrin-2
    of the sodium calcium exchanger in cardiomyocytes, which is clinically important because elevated expression of the sodium calcium exchanger is a factor...
    30 KB (3,443 words) - 14:40, 17 December 2024
  • Thumbnail for Sinoatrial node
    cytoplasm, also known as calcium sparks. This increase in calcium within the cell then activates a sodium-calcium exchanger (NCX), which removes one Ca2+...
    24 KB (2,808 words) - 19:51, 28 March 2025
  • Thumbnail for Digoxin
    of the sodium-calcium exchanger, which normally imports three extracellular sodium ions into the cell and transports one intracellular calcium ion out...
    47 KB (4,847 words) - 10:49, 22 March 2025