amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene. TAAR1 is an intracellular...

monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons...

Tryptamine can weakly activate the trace amine-associated receptor, TAAR1 (hTAAR1 in humans). Limited studies have considered tryptamine to be a trace...

stimulant effect. There is also evidence suggesting that N,N-DMPEA acts as a TAAR1 agonist in humans, and as a 5-HT1A ligand in rats. Some less conclusive...

neuronal TAAR1 mRNA expression, amphetamine is thought to affect norepinephrine analogously to dopamine. In other words, amphetamine induces TAAR1-mediated...

its parent compound, amphetamine, as they both are TAAR1 agonists, where the activation of TAAR1 in monoamine neurons facilitates the efflux, or release...

tyramine, called TAAR1. The TAAR1 receptor is found in the brain, as well as peripheral tissues, including the kidneys. Tyramine binds to TAAR1 as an agonist...

D2sh–TAAR1 The D2 receptor has been shown to form hetorodimers in vitro (and possibly in vivo) with DRD3, DRD5, and 5-HT2A. Prolactin modulator D2sh–TAAR1...

Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists – and hence, monoaminergic neuromodulators – that are structurally...

has been shown to activate TAAR1 in human astrocytes and generate cAMP as a result. Activation of astrocyte-localized TAAR1 appears to function as a mechanism...

amine-assorted receptor 1 (TAAR1), a G-Coupled Protein Receptor GPCR, to regulate monoaminergic systems in the brain. Active TAAR1 opposes the autoreceptor's...

and potent agonists of the trace amine-associated receptor 1 (TAAR1); agonism of TAAR1 triggers phosphorylation events that result in both non-competitive...

are a class of G protein-coupled receptors that were discovered in 2001. TAAR1, the first of six functional human TAARs, has gained considerable interest...

cloned human trace amine-associated receptor1 (TAAR1) and evidence for species differences with the rat TAAR1". The Journal of Pharmacology and Experimental...

amine-associated receptor TAAR1 (TAR1, TA1), a recently discovered G protein-coupled receptor. T1AM is the most potent endogenous TAAR1 agonist yet discovered...

dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) or in a TAAR1 independent fashion when there are high cytosolic concentrations...

formula of C9H13N. 3MPEA is a human trace amine associated receptor 1 (TAAR1) agonist, a property which it shares with its monomethylated phenethylamine...

properties. In particular, both amphetamine and β-methylphenethylamine are human TAAR1 agonists. In appearance, it is a colorless or yellowish liquid. Relatively...

bodily movement. Trace amines (endogenous amines that activate the human TAAR1 receptor) Phenethylamines (related to catecholamines): Phenethylamine (PEA)...

from their interactions with human trace amine-associated receptor 1 (hTAAR1) and vesicular monoamine transporter 2 (VMAT2) in neurons. Dextroamphetamine...

formula of C9H13N. 4MPEA is a human trace amine associated receptor 1 (TAAR1) agonist, a property which it shares with its monomethylated phenethylamine...

G protein-coupled receptors (i.e., TAAR1, TAAR2, TAAR5, TAAR6, TAAR8, and TAAR9) that – with exception for TAAR1 – are expressed in the human olfactory...

formula of C9H13N. 2MPEA is a human trace amine associated receptor 1 (TAAR1) agonist, a property which it shares with its monomethylated phenethylamine...

reported to enhance the activity of PE at TAAR1. Conversely, methylphenidate, ...showed poor efficacy at the TAAR1 receptor. In this respect it is worth noting...

by the activity of an intracellular trace amine-associated receptor, TAAR1. TAAR1 is a high-affinity receptor for dopamine, trace amines, and certain substituted...

isoprenaline can evoke α-AR-mediated responses. Its agonist effects at TAAR1 provide it with pharmacodynamic effects that resemble those of the endogenous...

countries, but banned in others. Pharmacologically, it is a phenol-based TAAR1 agonist and β adrenoreceptor agonist that stimulates β1 and β2 adrenergic...

studied so extensively as other related drugs. It is an agonist of human TAAR1. PMA Fenfluramine 2-Methoxymethamphetamine 3-Chloromethamphetamine...

amine-associated receptor 1 (TAAR1), with no significant activity at other targets. EPPTB is one of the first selective antagonists developed for TAAR1, and has been...

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and...