Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres...
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the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex. Telomerases are part of a distinct subgroup of RNA-dependent...
46 KB (5,304 words) - 20:19, 20 October 2024
each of human telomerase reverse transcriptase (TERT), Telomerase RNA Component (TR or TERC), and dyskerin (DKC1). The genes of telomerase subunits, which...
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Pseudoknot (category RNA)
The telomerase RNA component contains a pseudoknot that is critical for activity, and several viruses use a pseudoknot structure to form a tRNA-like...
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assembly and maturation of human telomerase RNA. Nonetheless, mutations that directly affect the telomerase RNA components would presumably exist and should...
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58 kilo-daltons. Dyskerin is essential for the activity of telomerase by accumulating telomerase RNA component (TERC). This gene is a member of the H/ACA snoRNPs...
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complementary RNA template region of telomerase. The complementary base pairing of the TERRA transcript may work to compete with telomerase's DNA substrate...
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snRNA component and several snRNP-specific proteins (including Sm proteins, a family of nuclear proteins). The most common human snRNA components of...
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Carol W. Greider (section Discovery of telomerase)
further test this idea mouse and human telomerase were characterized (1993) (1995) and the mouse telomerase RNA component was cloned (1995). During this time...
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RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...
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snoRNA to the single hairpin snoRNAs however, unlike trypanosomes, it has a regular ACA motif at 3′ tail.[19] The RNA component of human telomerase (hTERC)...
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strikingly similar to RNA and so may be surviving remnants of covalently bound coenzymes in an RNA world. One of the most critical components of cells, the ribosome...
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for the different types of RNA are listed and explained. List of cis-regulatory RNA elements RNA: Types of RNA Non-coding RNA Gribaldo S, Brochier-Armanet...
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are ancestral to human telomerase. The most famous example of RdRp is in the polio virus. The viral genome is composed of RNA, which enters the cell through...
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dysplasia (mutations in FoxF1) Mutations in telomerase reverse transcriptase (TERT) Mutations in telomerase RNA component (TERC) Mutations in the regulator of...
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Nucleic acid tertiary structure (redirect from RNA Tertiary Structure)
observed in human telomerase RNA (iii) the SAM-II riboswitch and (iv) the element for nuclear expression (ENE), which acts as an RNA stabilization element...
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transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
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Transcription (biology) (redirect from RNA transcription)
contain an enzyme with reverse transcription activity called telomerase. Telomerase carries an RNA template from which it synthesizes a telomere, a repeating...
58 KB (6,898 words) - 21:17, 23 March 2025
key component of pseudoknots as can be seen in the illustration of a naturally occurring pseudoknot found in the human telomerase RNA component. Four...
31 KB (3,451 words) - 20:17, 11 September 2024
ncRNAs from small non-coding RNAs, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs)...
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strand. Telomerase was shown to be a ribonucleoprotein enzyme that contains an RNA component that serves as a template strand, and a protein component that...
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is an enzyme for AIDS virus replication. Telomerase is an unusual polymerase because it contains its own RNA template as part of its structure. It synthesizes...
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(6): 1496–1499. PMID 5158754. Feng F; et al. (1995). "The RNA component of human telomerase". Science. 269 (5228): 1236–1241. Bibcode:1995Sci...269.1236F...
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Telomere (section Telomerase)
Weinrich SL, Avilion AA, Chiu CP, et al. (September 1995). "The RNA component of human telomerase". Science. 269 (5228): 1236–41. Bibcode:1995Sci...269.1236F...
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Nucleic acid secondary structure (redirect from RNA secondary structure)
biological processes rely on RNA molecules that form pseudoknots. For example, the RNA component of the human telomerase contains a pseudoknot that is...
18 KB (2,194 words) - 22:57, 24 February 2025
associated with telomerase assembly and recruitment via a CAB-RNA sequence common in both CB RNAs (scaRNAs) and the RNA component of telomerase (TERC). TCAB1...
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TERC may refer to: Telomerase RNA component, a human gene. TERC (Cambridge, Massachusetts), a nonprofit research and development organization in Cambridge...
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in situ hybridization test, detects amplification of the human telomerase RNA component (TERC) gene and/or polysomy of chromosome 3. Spectral karyotyping...
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and industry. His early work included the cloning of the RNA component of human telomerase when working at Geron Corporation, which led to his winning...
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interfering RNA (siRNA) and micro RNA (miRNA) to prevent mRNA translation and/or degrade mRNA. Small activating RNA (saRNA) represents a novel class of RNA therapeutics...
83 KB (9,545 words) - 10:23, 30 March 2025