Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene. The human TERF1 gene is located in the chromosome 8 at 73...
20 KB (2,474 words) - 21:38, 26 May 2025
Telomeric repeat-binding factor 2 is a protein that is present at telomeres throughout the cell cycle. It is also known as TERF2, TRF2, and TRBF2, and...
27 KB (3,340 words) - 22:06, 22 December 2023
Telomeric repeat–containing RNA (TERRA) is a long non-coding RNA transcribed from telomeres - repetitive nucleotide regions found on the ends of chromosomes...
46 KB (5,236 words) - 16:00, 22 May 2025
intermittent fasting Transfer RNA-derived fragment TERF1, Telomeric repeat-binding factor 1 (also known as TRF1) Sandefjord Airport, Torp, Norway, IATA...
1 KB (155 words) - 05:25, 25 April 2025
(Apr 2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel...
12 KB (1,493 words) - 17:10, 2 December 2023
G-quadruplex (section Telomeric quadruplexes)
Dash D, Chowdhury S (November 2019). "Telomere Repeat-Binding Factor 2 Binds Extensively to Extra-Telomeric G-quadruplexes and Regulates the Epigenetic Status...
95 KB (12,021 words) - 13:17, 23 May 2025
(Apr 2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel...
6 KB (663 words) - 04:37, 27 May 2025
telomere-binding protein refers to TTAGGG repeat binding factor-1 (TERF1) and TTAGGG repeat binding factor-2 (TERF2). Telomere sequences in humans are...
13 KB (1,658 words) - 04:45, 30 April 2025
(2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel...
7 KB (822 words) - 06:18, 5 January 2024
copy of exon 3 is present, telomeric to the D4Z4 repeat array. The open reading frame (ORF) is entirely contained within exon 1 and contains two homeoboxes...
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binds to the double-stranded repeat sequence of telomeres. HMBOX1 has originally been identified to associate with telomeric chromatin in telomerase-positive...
4 KB (452 words) - 01:09, 9 April 2022
Telomeric repeat-binding factor 2-interacting protein 1 also known as repressor activator protein 1 (Rap1) is a protein that in humans is encoded by the...
9 KB (1,161 words) - 18:14, 7 August 2022
Shelterin (category Telomere-binding proteins)
about ten times more abundant than TPP1 and POT1. TRF1 (Telomere Repeat binding Factor 1): TRF1 is a homodimeric protein that binds to the double-stranded...
21 KB (2,334 words) - 22:04, 20 September 2024
against decapentaplegic homolog 3 P53, PKMYT1, PLK1, SUPT5H, Telomeric repeat-binding factor 1, and Wee1-like protein kinase. GRCh38: Ensembl release 89:...
23 KB (2,792 words) - 20:16, 8 April 2024
mating type loci and at yeast telomeres, the transcription factors Abf1 (ARS binding factor) and Rap1 (repressor-activator protein) associate with specific...
19 KB (2,343 words) - 01:04, 3 December 2023
oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Nucleolin is also able to act as a...
17 KB (1,936 words) - 01:16, 28 July 2024
Microsatellite (redirect from Short tandem repeat)
replication problem". In white blood cells, the gradual shortening of telomeric DNA has been shown to inversely correlate with ageing in several sample...
67 KB (7,410 words) - 04:24, 18 May 2025
PMID 31072070. Cusanelli E, Chartrand P (May 2014). "Telomeric noncoding RNA: telomeric repeat-containing RNA in telomere biology". Wiley Interdisciplinary...
42 KB (4,774 words) - 17:56, 3 November 2024
human telomeric DNA in vitro. Beyond nucleic acid binding, FUS/TLS was also found to associate with both general and more specialized protein factors to...
32 KB (3,968 words) - 16:01, 6 February 2025
MeSH D12.776.660.235.700.750 – telomeric repeat binding protein 1 MeSH D12.776.660.235.700.875 – telomeric repeat binding protein 2 MeSH D12.776.660.352...
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inhibitory effect by binding to telomeric DNA. In the Late S/G2 phase, the protein kinase CDK1 (cyclin-dependent) promotes telomeric resection. This control...
18 KB (2,277 words) - 13:23, 26 November 2023
Antigenic variation (section HIV-1)
VSG genes become activated by gene conversion in a hierarchical order: telomeric VSGs are activated first, followed by array VSGs, and finally pseudogene...
25 KB (3,270 words) - 12:33, 4 December 2024
POT1 (category Telomere-binding proteins)
Podell ER, Cech TR (December 2004). "Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection". Nature...
12 KB (1,203 words) - 04:14, 2 June 2025
PURA (section Influence on HIV-1 replication)
number of repeats of this small sequence. N may be repeated up to three times in this sequence. Following the identification of a Pur factor, which specifically...
34 KB (4,047 words) - 17:10, 25 October 2023
Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA. Nat Struct Mol Biol. 2010 Apr;17(4):513-8 NCBI - telomerase...
50 KB (5,791 words) - 17:17, 23 May 2025
Cortactin (section Activation and binding)
in breast and squamous cell carcinomas encompasses three CpG islands telomeric of FGF3, including the expressed gene EMS1". Genes Chromosomes Cancer...
21 KB (2,576 words) - 11:30, 27 March 2024
targeted gene locus. The silencing activity of Sir2 is most prominent at telomeric sequences, the hidden MAT loci (HM loci), and the ribosomal DNA (rDNA)...
26 KB (3,129 words) - 22:13, 23 May 2025
FBXL7: F-box/LRR-repeat protein 7 FCHSD1: FCH and double SH3 domain protein 1 FGF1: fibroblast growth factor 1 (acidic fibroblast growth factor) FGFR4: fibroblast...
32 KB (2,298 words) - 14:32, 20 April 2025
vertebrate telomeric DNA consists of long (TTAGGG)n repeats of variable length, often around 3-20kb. Subtelomeres are segments of DNA between telomeric caps...
23 KB (2,747 words) - 01:10, 27 May 2025