Tetraloops are a type of four-base hairpin loop motifs in RNA secondary structure that cap many double helices. There are many variants of the tetraloop...
7 KB (844 words) - 09:30, 23 June 2025
interactions. Tetraloop-receptor interactions combine base-pairing and stacking interactions between the loop nucleotides of a tetraloop motif and a receptor...
54 KB (6,395 words) - 12:46, 20 June 2025
adenosine residue of the helix 6 GNAR tetraloop motif. The SRP RNAs of eukaryotes and Archaea have a GNAR tetraloop (N is for any nucleotide, R is for a...
33 KB (3,769 words) - 06:11, 29 October 2024
commonly stabilize loops, junctions, and recurrent 3D motifs such as GNRA tetraloops. Non-canonical base pairs are often located in loops, bulges, and junctions...
90 KB (11,794 words) - 09:24, 23 June 2025
of triplet repeats is odd or even. An even number of repeats forms a tetraloop structure, while an odd number leads to the formation of a triloop. In...
61 KB (7,967 words) - 03:11, 24 June 2025
region called the 'loop'. A tetraloop is a four-base pairs hairpin RNA structure. There are three common families of tetraloop in ribosomal RNA: UNCG, GNRA...
18 KB (2,416 words) - 16:16, 5 December 2024
are unstable. One common loop with the sequence UUCG is known as the "tetraloop," and is particularly stable due to the base-stacking interactions of...
6 KB (739 words) - 21:09, 14 October 2024
group of adenine bases binding to each other in a bulge, or the GNRA tetraloop that has a guanine–adenine base-pair. The chemical structure of RNA is...
66 KB (7,668 words) - 11:49, 23 June 2025
crystal structures, as exemplified by the determination of an isolated tetraloop-receptor motif structure published in 1997. Investigations such as this...
58 KB (7,633 words) - 06:08, 22 June 2025
interaction loop of domain 3 is known as GNRA tetraloop. The residues of adenosines A180 and A181 in the GUAA tetraloop form hydrogen bonds via non canonical...
53 KB (6,721 words) - 07:48, 19 March 2025
(2000). "Solution structure of Cobalt(III)hexammine complexed to the GAAA tetraloop, and metal-ion binding to G.A mismatches". J. Mol. Biol. 295 (5): 1211–1232...
9 KB (696 words) - 10:29, 20 June 2025
shown that the apical loop to be capped by a stable well-structured UGUU tetraloop. HBV RNA encapsidation signal epsilon "Rfam: Family: AHBV_epsilon (RF01313)"...
4 KB (400 words) - 00:51, 19 May 2025
structure that was discovered by bioinformatics. Energetically stable tetraloops often occur in this motif. The Methylophilales-1 motif is found in Methylophilales...
1 KB (99 words) - 20:42, 7 December 2021
Each domain contains normal secondary structure (e.g., base triple, tetraloop, cross-strand purine stack) and is also highly symmetric in tertiary structure;...
13 KB (1,476 words) - 00:25, 5 February 2025
number of tertiary contacts between motifs, including kissing-loop and tetraloop-receptor interactions. In 2005, A. De Lencastre et al. found that during...
16 KB (2,099 words) - 02:34, 24 June 2025
Cas9 endonuclease activity. These two components are linked by a short tetraloop structure, resulting in the formation of the sgRNA. The tracrRNA consist...
30 KB (3,644 words) - 14:03, 23 May 2025
these elements or combinations of them can be further classified, e.g. tetraloops, pseudoknots and stem loops. There are many secondary structure elements...
22 KB (2,601 words) - 15:55, 4 May 2025
further classified into additional categories including, for example, tetraloops, pseudoknots, and stem-loops. Topological approaches can be used to categorize...
24 KB (2,867 words) - 02:27, 30 June 2025
structure that was discovered by bioinformatics. Energetically stable tetraloops often occur in this motif. Proteo-phage-1 motif RNAs are found in Pseudomonadota...
2 KB (155 words) - 19:44, 2 May 2022
contain terminal loops conforming to the stable UNCG tetraloop, but the DNA version of this tetraloop (TNCG) is not especially stable. The STAXI motif consists...
2 KB (211 words) - 05:06, 1 December 2023
Betaproteobacteria, and Thermodesulfobacteriota. Energetically stable tetraloops often occur in this motif. COG3860 motif RNAs likely function as cis-regulatory...
2 KB (125 words) - 08:38, 11 October 2024
terminus of the stem designated as "P2" very often conforms to highly stable tetraloop motifs that were previously elucidated, conforming to the consensus GNRA...
6 KB (654 words) - 01:39, 3 December 2023
from base pairing, and many stem-loops are terminated by the stable UNCG tetraloop. Most of the conserved nucleotides in the motif participate in standard...
4 KB (431 words) - 08:27, 3 December 2023
structure that was discovered by bioinformatics. Energetically stable tetraloops often occur in this motif. Parabacteroides-1 motif RNAs are found in Parabacteroides...
2 KB (132 words) - 23:15, 15 December 2022
alpha-sarcin toxin that targets it. The targeted bond is located within the GAGA tetraloop of the RNA in between a guanine and adenine nucleotide. Other ribotoxins...
7 KB (922 words) - 00:15, 31 December 2024
structure that was discovered by bioinformatics. Energetically stable tetraloops often occur in this motif. Prevotella-2 motif RNAs are found in the bacterial...
2 KB (224 words) - 20:45, 7 December 2021
by a novel three-helix bundle fold. SLBP proteins also recognize the tetraloop structure of the histone hairpin, the base of the stem, and the 5' flanking...
11 KB (1,505 words) - 08:26, 3 December 2022
stem-loops (see diagram), the second of which is often terminated by a CUUG tetraloop, which is an energetically favorable RNA sequence. Whalefall-1 RNAs are...
2 KB (183 words) - 02:20, 28 November 2023
sequence GCGA, and these sequences might in some cases form stable GNRA tetraloops. Since the two stem-loops are somewhat distant from one another it is...
2 KB (176 words) - 03:27, 3 December 2023
structure that was discovered by bioinformatics. Energetically stable tetraloops often occur in this motif. sul1 motif RNAs are found in Alphaproteobacteria...
3 KB (252 words) - 21:34, 24 July 2022