Thioflavins are fluorescent dyes that are available as at least two compounds, namely Thioflavin T and Thioflavin S. Both are used for histology staining...
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Pittsburgh compound B (PiB) is a radioactive analog of thioflavin T, which can be used in positron emission tomography scans to image beta-amyloid plaques...
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fluorescent. Thioflavin T is obtained by the methylation of dehydrothiotoluidine with methanol in the presence of hydrochloric acid. Thioflavin S results...
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and an ability to stain with specific dyes, such as Congo red, thioflavin T or thioflavin S. The term "cross-β" was based on the observation of two sets...
60 KB (6,514 words) - 10:39, 27 March 2024
confocal microscopy, Congo red can be used as a stable fluorescent stain. Thioflavin Klaus Hunger, Peter Mischke, Wolfgang Rieper, Roderich Raue, Klaus Kunde...
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fluorimetry equipment. Thioflavins are dyes used for histology staining and biophysical studies of protein aggregation. For example, thioflavin T is used in the...
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solanezumab. Imaging compounds, notably Pittsburgh compound B, (6-OH-BTA-1, a thioflavin), can selectively bind to amyloid beta in vitro and in vivo. This technique...
43 KB (4,769 words) - 15:53, 8 May 2024
McLellan ME, Frosch MP, Hyman BT, et al. (February 2002). "A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid...
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electron-withdrawing moiety with numerous applications in dyes such as thioflavin. Some drugs contain this group, examples being riluzole and pramipexole...
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same core structure as amyloid fibrils, and is positive to Congo red and thioflavin T. The monolayer formed by class I hydrophobins has a highly ordered structure...
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light, makes the amyloid proteins appear apple-green on microscopy. Also, thioflavin T stain may be used. A number of imaging techniques such as a Nuclear...
55 KB (5,432 words) - 21:07, 18 April 2024
a variety of staining techniques, including silver stains, Congo red, Thioflavin, cresyl violet, PAS-reaction, and luminescent conjugated oligothiophenes...
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prepare full-length α-synuclein with an O-GlcNAc modification at T72. Thioflavin T aggregation assays and transmission electron microscopy demonstrated...
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human brain using PET scanning, and which is a fluorescent analog of thioflavin T. For his work on Alzheimer's disease he has received the Metlife Foundation...
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g/mol) may refer to: Chlorpromazine, the oldest typical antipsychotic Thioflavin, two dyes used for histology staining This set index page lists chemical...
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alpha-synuclein have been described that are invisible to the amyloid dye Thioflavin T and that can acutely spread in neurons in vitro and in vivo. Antibodies...
83 KB (9,450 words) - 20:34, 27 April 2024
Krebs, M.R.H.; Bromley, E.H.C.; Donald, A.M. (2005). "The binding of thioflavin-T to amyloid fibrils: Localisation and implications". Journal of Structural...
28 KB (2,450 words) - 21:16, 11 May 2024
McLellan ME, Frosch MP, Hyman BT, et al. (February 2002). "A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid...
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of normally folded prions. These protein aggregates can be detected by thioflavin T visible spectrum fluorescence detection. The Centers for Disease Control...
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Nerve sheath myxoma (Cellular neurothekeoma) Extraskeletal chondroma Thioflavin T Amyloidosis Colloid milium Toluidine blue Mast cell Mastocytosis Mucopolysaccharidoses...
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bromide (DMSB), crystal violet, berberine neutral red, thioflavin T, and perylene tetracarboxylic acid diimide derivative (PTCDI), originally...
54 KB (7,083 words) - 13:28, 17 February 2024
et al. (2004). "Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of...
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fluorescent emission test could be applied to amyloid fibrils by using the dye Thioflavin T that binds specifically to the peptide and emits blue fluorescence when...
30 KB (3,875 words) - 02:56, 19 December 2023