Total synthesis, a specialized area within organic chemistry, focuses on constructing complex organic compounds, especially those found in nature, using...
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The total synthesis of the complex biomolecule vitamin B12 was accomplished in two different approaches by the collaborating research groups of Robert...
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Strychnine total synthesis in chemistry describes the total synthesis of the complex biomolecule strychnine. The first reported method by the group of...
39 KB (4,087 words) - 03:50, 29 February 2024
Synthesis of morphine-like alkaloids in chemistry describes the total synthesis of the natural morphinan class of alkaloids that includes codeine, morphine...
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The total synthesis of quinine, a naturally-occurring antimalarial drug, was developed over a 150-year period. The development of synthetic quinine is...
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Diverted total synthesis in chemistry is a strategy in drug discovery aiming at organic synthesis of natural product analogues rather than the natural...
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The article concerns the total synthesis of galanthamine, a drug used for the treatment of mild to moderate Alzheimer's disease. The natural source of...
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Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). This diterpenoid is an...
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Holton Taxol total synthesis, published by Robert A. Holton and his group at Florida State University in 1994, was the first total synthesis of Taxol (generic...
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Oseltamivir total synthesis concerns the total synthesis of the anti-influenza drug oseltamivir marketed by Hoffmann-La Roche under the trade name Tamiflu...
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organic synthesis, there are many different types of synthetic routes that can be completed including total synthesis, stereoselective synthesis, automated...
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The Nicolaou Taxol total synthesis, published by K. C. Nicolaou and his group in 1994 concerns the total synthesis of taxol. Taxol is an important drug...
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Cholesterol total synthesis in chemistry describes the total synthesis of the complex biomolecule cholesterol and is considered a great scientific achievement...
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the total synthesis of akuammiline natural products. The method has also been used in medicinal chemistry. Indometacin preparation. Triptan synthesis Iprindole...
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Steroid (redirect from Steroid synthesis)
industry. Some steroidal hormones are economically obtained only by total synthesis from petrochemicals (e.g. 13-alkyl steroids). For example, the pharmaceutical...
84 KB (8,672 words) - 20:49, 24 May 2025
Aflatoxin total synthesis concerns the total synthesis of a group of organic compounds called aflatoxins. These compounds occur naturally in several fungi...
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Gesamtkunstwerk (redirect from Synthesis of the arts)
Gesamtkunstwerk (German: [ɡəˈzamtˌkʊnstvɛʁk] , 'total work of art', 'ideal work of art', 'universal artwork', 'synthesis of the arts', 'comprehensive artwork',...
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Electrosynthesis Methods in Organic Synthesis Organic synthesis Peptide synthesis Total synthesis Automated synthesis Vogel, A.I.; Tatchell, A.R.; Furnis...
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contiguous stereocenters. Azomethine ylides thus have high utility in total synthesis, and formation of chiral ligands and pharmaceuticals. Azomethine ylides...
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Elias James Corey (section Total syntheses)
numerous synthetic reagents, methodologies and total syntheses and has advanced the science of organic synthesis considerably. E.J. Corey (the surname was...
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convergent synthesis is a strategy that aims to improve the efficiency of multistep synthesis, most often in organic synthesis. In this type of synthesis several...
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Retrieved 9 May 2022. Sheehan JC, Henery-Logan KR (March 5, 1957). "The Total Synthesis of Penicillin V". Journal of the American Chemical Society. 79 (5):...
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Natural product (redirect from Natural product synthesis)
Natural products can also be prepared by chemical synthesis (both semisynthesis and total synthesis and have played a central role in the development...
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to metallating reagents. Both these synthetic routes pose issues in total synthesis. In 1984 a new synthetic strategy was developed by Rick Danheiser to...
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The Danishefsky Taxol total synthesis in organic chemistry is an important third Taxol synthesis published by the group of Samuel Danishefsky in 1996 two...
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group discovered the total synthesis of talatisamine (a C19-norditerpenoid). In the subsequent years, they also discovered the total syntheses of other...
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Diels–Alder reaction (redirect from Diene synthesis)
Grzejszczak, S. (1987). "General strategies for the synthesis of indole alkaloids. Total synthesis of (±)-reserpine and (±)-α-yohimbine". Journal of the...
69 KB (7,937 words) - 05:25, 26 May 2025
QS-21 (section Total synthesis)
made by total chemical synthesis, but required an inefficient 76-step process that is not commercially viable. This is not unlike the total chemical...
11 KB (1,224 words) - 04:24, 21 April 2025
1021/jo00296a004. Trost, B. M.; Nishimura, Yoshio; Yamamoto, Kagetoshi (1979). "A Total Synthesis of Aphidicolin". J. Am. Chem. Soc. 101 (5): 1328. doi:10.1021/ja00499a071...
31 KB (3,524 words) - 01:29, 3 January 2025
Morphine (section Chemical synthesis)
The first morphine total synthesis, devised by Marshall D. Gates, Jr. in 1952, remains a widely used example of total synthesis. Several other syntheses...
143 KB (14,053 words) - 04:08, 26 May 2025