• Total synthesis, a specialized area within organic chemistry, focuses on constructing complex organic compounds, especially those found in nature, using...
    22 KB (2,203 words) - 21:09, 12 March 2025
  • The total synthesis of the complex biomolecule vitamin B12 was accomplished in two different approaches by the collaborating research groups of Robert...
    132 KB (7,466 words) - 06:37, 11 March 2025
  • Thumbnail for Strychnine total synthesis
    Strychnine total synthesis in chemistry describes the total synthesis of the complex biomolecule strychnine. The first reported method by the group of...
    39 KB (4,087 words) - 03:50, 29 February 2024
  • Thumbnail for Total synthesis of morphine and related alkaloids
    Synthesis of morphine-like alkaloids in chemistry describes the total synthesis of the natural morphinan class of alkaloids that includes codeine, morphine...
    10 KB (948 words) - 16:07, 23 May 2025
  • The total synthesis of quinine, a naturally-occurring antimalarial drug, was developed over a 150-year period. The development of synthetic quinine is...
    18 KB (2,189 words) - 19:10, 21 May 2025
  • Thumbnail for Diverted total synthesis
    Diverted total synthesis in chemistry is a strategy in drug discovery aiming at organic synthesis of natural product analogues rather than the natural...
    6 KB (619 words) - 19:44, 27 October 2022
  • Thumbnail for Galantamine total synthesis
    The article concerns the total synthesis of galanthamine, a drug used for the treatment of mild to moderate Alzheimer's disease. The natural source of...
    15 KB (1,662 words) - 02:08, 18 September 2024
  • Thumbnail for Paclitaxel total synthesis
    Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). This diterpenoid is an...
    16 KB (1,961 words) - 12:34, 25 May 2025
  • Thumbnail for Holton Taxol total synthesis
    Holton Taxol total synthesis, published by Robert A. Holton and his group at Florida State University in 1994, was the first total synthesis of Taxol (generic...
    16 KB (1,478 words) - 23:58, 18 February 2025
  • Thumbnail for Oseltamivir total synthesis
    Oseltamivir total synthesis concerns the total synthesis of the anti-influenza drug oseltamivir marketed by Hoffmann-La Roche under the trade name Tamiflu...
    20 KB (2,311 words) - 18:00, 17 January 2025
  • organic synthesis, there are many different types of synthetic routes that can be completed including total synthesis, stereoselective synthesis, automated...
    25 KB (2,550 words) - 17:17, 25 May 2025
  • Thumbnail for Nicolaou Taxol total synthesis
    The Nicolaou Taxol total synthesis, published by K. C. Nicolaou and his group in 1994 concerns the total synthesis of taxol. Taxol is an important drug...
    18 KB (1,520 words) - 17:15, 19 January 2024
  • Thumbnail for Cholesterol total synthesis
    Cholesterol total synthesis in chemistry describes the total synthesis of the complex biomolecule cholesterol and is considered a great scientific achievement...
    9 KB (1,102 words) - 20:48, 10 March 2025
  • the total synthesis of akuammiline natural products. The method has also been used in medicinal chemistry. Indometacin preparation. Triptan synthesis Iprindole...
    9 KB (793 words) - 11:35, 25 May 2025
  • Thumbnail for Steroid
    Steroid (redirect from Steroid synthesis)
    industry. Some steroidal hormones are economically obtained only by total synthesis from petrochemicals (e.g. 13-alkyl steroids). For example, the pharmaceutical...
    84 KB (8,672 words) - 20:49, 24 May 2025
  • Thumbnail for Aflatoxin total synthesis
    Aflatoxin total synthesis concerns the total synthesis of a group of organic compounds called aflatoxins. These compounds occur naturally in several fungi...
    5 KB (567 words) - 03:43, 5 January 2024
  • Thumbnail for Gesamtkunstwerk
    Gesamtkunstwerk (German: [ɡəˈzamtˌkʊnstvɛʁk] , 'total work of art', 'ideal work of art', 'universal artwork', 'synthesis of the arts', 'comprehensive artwork',...
    33 KB (3,528 words) - 18:17, 20 February 2025
  • Electrosynthesis Methods in Organic Synthesis Organic synthesis Peptide synthesis Total synthesis Automated synthesis Vogel, A.I.; Tatchell, A.R.; Furnis...
    11 KB (1,128 words) - 14:30, 25 May 2025
  • Thumbnail for Azomethine ylide
    contiguous stereocenters. Azomethine ylides thus have high utility in total synthesis, and formation of chiral ligands and pharmaceuticals. Azomethine ylides...
    18 KB (1,988 words) - 01:46, 19 April 2024
  • Thumbnail for Elias James Corey
    numerous synthetic reagents, methodologies and total syntheses and has advanced the science of organic synthesis considerably. E.J. Corey (the surname was...
    56 KB (5,744 words) - 20:06, 25 May 2025
  • Thumbnail for Convergent synthesis
    convergent synthesis is a strategy that aims to improve the efficiency of multistep synthesis, most often in organic synthesis. In this type of synthesis several...
    2 KB (273 words) - 19:25, 27 October 2022
  • Thumbnail for Penicillin
    Retrieved 9 May 2022. Sheehan JC, Henery-Logan KR (March 5, 1957). "The Total Synthesis of Penicillin V". Journal of the American Chemical Society. 79 (5):...
    100 KB (10,774 words) - 18:15, 24 May 2025
  • Thumbnail for Natural product
    Natural products can also be prepared by chemical synthesis (both semisynthesis and total synthesis and have played a central role in the development...
    116 KB (12,419 words) - 12:19, 7 May 2025
  • to metallating reagents. Both these synthetic routes pose issues in total synthesis. In 1984 a new synthetic strategy was developed by Rick Danheiser to...
    19 KB (2,079 words) - 02:21, 9 January 2025
  • Thumbnail for Danishefsky Taxol total synthesis
    The Danishefsky Taxol total synthesis in organic chemistry is an important third Taxol synthesis published by the group of Samuel Danishefsky in 1996 two...
    15 KB (1,399 words) - 13:35, 26 August 2024
  • Thumbnail for Aconitine
    group discovered the total synthesis of talatisamine (a C19-norditerpenoid). In the subsequent years, they also discovered the total syntheses of other...
    35 KB (3,643 words) - 05:45, 29 April 2025
  • Thumbnail for Diels–Alder reaction
    Grzejszczak, S. (1987). "General strategies for the synthesis of indole alkaloids. Total synthesis of (±)-reserpine and (±)-α-yohimbine". Journal of the...
    69 KB (7,937 words) - 05:25, 26 May 2025
  • Thumbnail for QS-21
    made by total chemical synthesis, but required an inefficient 76-step process that is not commercially viable. This is not unlike the total chemical...
    11 KB (1,224 words) - 04:24, 21 April 2025
  • 1021/jo00296a004. Trost, B. M.; Nishimura, Yoshio; Yamamoto, Kagetoshi (1979). "A Total Synthesis of Aphidicolin". J. Am. Chem. Soc. 101 (5): 1328. doi:10.1021/ja00499a071...
    31 KB (3,524 words) - 01:29, 3 January 2025
  • Thumbnail for Morphine
    The first morphine total synthesis, devised by Marshall D. Gates, Jr. in 1952, remains a widely used example of total synthesis. Several other syntheses...
    143 KB (14,053 words) - 04:08, 26 May 2025