Transporter associated with antigen processing (TAP) protein complex belongs to the ATP-binding-cassette transporter family. It delivers cytosolic peptides...
7 KB (838 words) - 04:39, 30 July 2025
Antigen processing, or the cytosolic pathway, is an immunological process that prepares antigens for presentation to special cells of the immune system...
13 KB (1,763 words) - 22:30, 2 June 2025
(ER) via the action of heat shock proteins and the transporter associated with antigen processing (TAP) which translocates the cytosolic peptides into...
14 KB (1,670 words) - 17:04, 24 May 2025
studying protein interactions Timor–Alor–Pantar languages Transporter associated with antigen processing (TAP), a protein complex 2,4,6-triaminopyrimidine (TAP)...
6 KB (811 words) - 20:11, 20 July 2025
Tapasin (category Articles with short description)
class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic...
14 KB (1,723 words) - 04:27, 30 July 2025
TAP1 (category ATP-binding cassette transporters)
Transporter associated with antigen processing 1 (TAP1) is a protein that in humans is encoded by the TAP1 gene. A member of the ATP-binding cassette transporter...
10 KB (1,215 words) - 07:27, 19 July 2025
Herpes simplex virus (category Articles with short description)
interference with MHC class I antigen presentation on the cell surface, by blocking the transporter associated with antigen processing (TAP) induced...
69 KB (7,542 words) - 23:28, 17 July 2025
Peptide-loading complex (category All articles with unsourced statements)
assembly consists of seven subunits, including the transporters associated with antigen processing (TAP1 and TAP2 – jointly referred to as TAP), the oxidoreductase...
12 KB (1,550 words) - 06:13, 30 July 2025
Membrane-associated transporter protein (MATP), also known as solute carrier family 45 member 2 (SLC45A2) or melanoma antigen AIM1, is a protein that in...
12 KB (1,331 words) - 19:11, 22 July 2025
MHC class I (redirect from Histocompatibility antigens class i)
the ER is accomplished by the transporter associated with antigen processing (TAP). TAP is a member of the ABC transporter family and is a heterodimeric...
24 KB (2,930 words) - 04:29, 30 July 2025
"Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing". The EMBO Journal. 20 (17): 4964–72. doi:10.1093/emboj/20...
111 KB (14,448 words) - 00:51, 28 May 2025
Bare lymphocyte syndrome (redirect from Antigen-peptide-transporter 2 deficiency)
class I deficiency" is associated with TAP2, TAP1, or TAPBP deficiencies. TAP (Transporter associated with antigen processing) proteins are involved in...
7 KB (689 words) - 00:33, 25 May 2025
Cancer immunology (category Articles with short description)
antigen presentation pathway, what leads into down-regulation of tumor antigen presentations. Defects are for example in transporter associated with antigen...
33 KB (3,766 words) - 14:14, 19 June 2024
Major histocompatibility complex (redirect from MHC antigen)
of MHC molecules, which is to bind an antigen derived from self-proteins, or from pathogens, and bring the antigen presentation to the cell surface for...
58 KB (6,838 words) - 07:32, 30 July 2025
Calreticulin (category Articles with short description)
with ERp57) takes over the job of chaperoning the MHC class I protein while the tapasin links the complex to the transporter associated with antigen processing...
20 KB (2,452 words) - 04:28, 30 July 2025
HLA-E (category Articles with short description)
proteasome. Upon transport into the ER lumen by the transporter associated with antigen processing (TAP), these peptides bind to a peptide binding groove...
7 KB (954 words) - 06:03, 19 July 2025
Red blood cell (category Articles with short description)
cycle.; Kidd antigen protein – urea transporter; RHAG – gas transporter, probably of carbon dioxide, defines Rh Blood Group and the associated unusual blood...
65 KB (7,853 words) - 10:47, 20 July 2025
Calnexin (category Articles with short description)
complex to the transporter associated with antigen processing (TAP) complex. This association prepares the MHC class I for binding an antigen for presentation...
18 KB (2,214 words) - 02:03, 19 May 2025
Genetic vaccine (category Articles with short description)
are imported into the endoplasmic reticulum via the transporter associated with antigen processing, allowing them to bind to MHCI-molecules that are subsequently...
8 KB (1,186 words) - 14:18, 8 June 2025
Serotype (category Articles with short description)
antibodies is the O antigen. Variation in the O antigen can be caused by genetic differences in the biosynthetic pathway or the transporter used to move the...
20 KB (2,200 words) - 18:35, 16 July 2025
Cross-presentation (category Articles with short description)
certain professional antigen-presenting cells (mostly dendritic cells) to take up, process and present extracellular antigens with MHC class I molecules...
18 KB (2,159 words) - 21:24, 20 November 2024
Multidrug resistance-associated protein 2 (MRP2) also called canalicular multispecific organic anion transporter 1 (cMOAT) or ATP-binding cassette sub-family...
17 KB (1,709 words) - 22:01, 15 July 2025
HM13 (category Articles with short description)
lumen by the transporter associated with antigen processing (TAP) and is presented on the cell surface on H2-Db major histocompatibility antigen I (MHC I)...
9 KB (1,137 words) - 04:15, 15 July 2025
T-cell receptor (redirect from Alpha-beta T-cell antigen receptor)
recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively...
44 KB (5,378 words) - 07:54, 5 May 2025
4F2 cell-surface antigen heavy chain is a protein that in humans is encoded by the SLC3A2 (solute carrier family 3 member 2) gene. SLC3A2 comprises the...
13 KB (1,597 words) - 15:29, 17 July 2025
Lipopolysaccharide (redirect from O antigen)
molecules consisting of three parts: an outer core polysaccharide termed the O-antigen, an inner core oligosaccharide and Lipid A (from which toxicity is largely...
63 KB (7,214 words) - 09:40, 17 July 2025
"Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing". EMBO J. 20 (17): 4964–72. doi:10.1093/emboj/20.17...
4 KB (429 words) - 04:12, 7 November 2023
Basigin (redirect from OK antigen system)
is a determinant for the Ok blood group system. There are three known antigens in the Ok system; the most common being Oka (also called OK1), OK2 and...
22 KB (2,517 words) - 21:25, 15 July 2025
TAP2 (category ATP-binding cassette transporters)
TAP2 is a gene in humans that encodes the protein Antigen peptide transporter 2. The membrane-associated protein encoded by this gene is a member of the...
9 KB (1,208 words) - 18:44, 16 July 2025
Some of these antigens are ubiquitously expressed in nucleated male cells, and the presence of these antigens has been associated with a greater risk...
18 KB (1,681 words) - 19:29, 24 May 2025