U.S. Highway 8 (US 8) is a United States Numbered Highway that runs primarily east–west for 280 miles (451 km), mostly within the state of Wisconsin. It...

U.S. Route 202 (US 202) is a spur route of US 2. It follows a northeasterly and southwesterly direction stretching from Delaware in the south to Maine...

U.S. Route 191 (US 191) is a north–south highway in the Western United States and a spur of parent route U.S. Route 91 that has two segments. The southern...

U.S. Route 66 or U.S. Highway 66 (US 66 or Route 66) is one of the original highways in the United States Numbered Highway System. It was established on...

U.S. Route 190 (US 190) is an east–west United States Highway in Louisiana and Texas. Segments of US 190 will be upgraded to Interstate 14 (I-14); the...

U.S. Route 380 (US 380) is an east–west United States highway. The highway's eastern terminus is in Greenville, Texas at an intersection with Interstate...

U.S. Route 70 or U.S. Highway 70 (US 70) is an east–west United States highway that runs for 2,381 miles (3,832 km) from eastern North Carolina to east-central...

U.S. Route 167 is a north-south United States Highway within the U.S. states of Louisiana and Arkansas. It runs for 500 miles (800 km) from Ash Flat, Arkansas...

U.S. Route 91 or U.S. Highway 91 (US 91) is a 172.7-mile-long (277.9 km) north–south United States highway running from Brigham City, Utah, to Idaho Falls...

U.S. Route 501 (US 501) is a spur of U.S. Route 1. It runs 355 miles (571 km) from Buena Vista, Virginia at U.S. Route 60 to Myrtle Beach, South Carolina...

U.S. Route 160 (US 160) is a 1,465-mile-long (2,358 km) east–west United States Numbered Highway in the Midwestern and Western United States. The western...

U.S. Route 21 or U.S. Highway 21 (US 21) is a north–south United States Numbered Highway, spanning 393 miles (632 km) from Hunting Island State Park, South...

U.S. Route 301 (US 301) is a spur of U.S. Route 1 running through the South Atlantic states. It runs 1,099 miles (1,769 km) from Biddles Corner, Delaware...

U.S. Route 277 (US 277, US-277) is a north–south United States Highway that is a spur route of U.S. Route 77. It no longer connects to its parent route...

Several special routes of U.S. Route 30 exist. In order from west to east they are as follows. U.S. Route 30 Business (US 30 Bus.) in St. Helens, Oregon...

U.S. Route 165 is a north–south United States highway spur of U.S. Highway 65. It currently runs for 412 miles (663 km) from U.S. Route 90 in Iowa, Louisiana...

U.S. Route 3 (US 3) is a United States Numbered Highway running 277.90 miles (447.24 km) from Cambridge, Massachusetts, through New Hampshire, to the Canada–United...

U.S. Route 17 or U.S. Highway 17 (US 17), also known as the Coastal Highway, is a north–south United States Numbered Highway that spans in the Southeastern...

U.S. Route 53, or U.S. Highway 53 (U.S. 53), is a north–south U.S. highway that runs for 404 miles (650 km) from La Crosse, Wisconsin to International...

U.S. Route 49 (US 49) is a north–south United States highway. The highway's northern terminus is in Piggott, Arkansas, at an intersection with U.S. Route...

U.S. Route 302 (US 302) is an east–west spur of U.S. Route 2 in northern New England in the United States. It currently runs 171 miles (275 km) from Montpelier...

U.S. Route 2 or U.S. Highway 2 (US 2) is an east–west United States Numbered Highway spanning 2,571 miles (4,138 km) across the northern continental United...

U.S. Route 20 or U.S. Highway 20 (US 20) is an east–west United States Numbered Highway that stretches from the Pacific Northwest east to New England....

U.S. Route 68 (US 68) is a United States highway that runs for 560 miles (900 km) from northwest Ohio to Western Kentucky. The highway's western terminus...

U.S. Route 58 (US 58) is an east–west U.S. Highway that runs for 508 miles (818 km) from U.S. Route 25E just northwest of Harrogate, Tennessee, to U.S...

U.S. Route 321 (US 321) is a spur of U.S. Route 21. It runs for 516.9 miles (831.9 km) from Hardeeville, South Carolina to Lenoir City, Tennessee; with...

U.S. Route 158 (US 158) is an east–west United States highway that runs for 350 miles (560 km) from Mocksville to Whalebone Junction in Nags Head, and...

U.S. Route 10 or U.S. Highway 10 (US 10) is an east–west United States Numbered Highway located in the Midwest and Great Lakes regions of the U.S. Despite...

Numerous special routes of U.S. Route 67, all business routes, exist. One other route, formerly an alternate route in western Illinois, has since been...

U.S. Route 80 or U.S. Highway 80 (US 80) is a major east–west United States Numbered Highway in the Southern United States, much of which was once part...