• Thumbnail for Williamson ether synthesis
    The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and a deprotonated alcohol (alkoxide). This reaction was...
    11 KB (1,318 words) - 21:17, 4 February 2025
  • Thumbnail for Alexander William Williamson
    Williamson FRS FRSE PCS MRIA (1 May 1824 – 6 May 1904) was an English chemist. He is best known today for the Williamson ether synthesis. Williamson was...
    12 KB (1,102 words) - 00:56, 1 May 2025
  • Thumbnail for Phenol ether
    in the laboratory. Bis-aryl ethers (such as diphenyl ether) cannot be synthesized through the Williamson ether synthesis, however, as aryl halides cannot...
    10 KB (1,142 words) - 09:48, 15 April 2024
  • Thumbnail for Ether
    halides by alkoxides R–ONa + R′–X → R–O–R′ + NaX This reaction, the Williamson ether synthesis, involves treatment of a parent alcohol with a strong base to...
    19 KB (1,841 words) - 14:31, 5 May 2025
  • same way other symmetrical ethers may be formed. This ether may also be prepared by way of the Williamson ether synthesis in which n-propoxide, the conjugate...
    4 KB (248 words) - 02:33, 15 March 2025
  • Alexander Williamson may refer to: Alexander William Williamson (1824–1904), chemist who discovered the Williamson ether synthesis reaction Alexander Williamson...
    649 bytes (107 words) - 10:23, 14 March 2025
  • Thumbnail for Alkoxide
    occur widely as intermediates in various reactions, including the Williamson ether synthesis. Transition metal alkoxides are widely used for coatings and as...
    10 KB (1,008 words) - 21:11, 11 December 2024
  • first designed in 1947 Williamson Road Junior Public School, an elementary school in Toronto, Ontario Williamson ether synthesis, one of the most common...
    1 KB (153 words) - 03:50, 28 April 2024
  • Thumbnail for Diphenyl ether
    its derivatives. Now it is synthesized by a modification of the Williamson ether synthesis, here the reaction of phenol and bromobenzene in the presence...
    8 KB (734 words) - 01:37, 11 March 2025
  • Thumbnail for Anisole
    Anisole (redirect from Methyl phenyl ether)
    (CH3OC6H4COO)2Ba → 2 CH3OC6H5 + BaCO3 It can be prepared by the Williamson ether synthesis from sodium phenoxide and dimethyl sulfate or methyl chloride:...
    9 KB (809 words) - 17:45, 6 November 2024
  • Alexander W. Williamson may refer to: Alexander William Williamson (1824–1904), chemist who discovered the Williamson ether synthesis reaction Alexander...
    272 bytes (59 words) - 10:18, 14 March 2025
  • Thumbnail for Piperonal
    α-hydroxy acid with an oxidizing agent. Synthesis from catechol requires an additional step, Williamson ether synthesis using dichloromethane. Piperonal, like...
    9 KB (748 words) - 16:08, 17 December 2024
  • Thumbnail for Trimethyl orthoformate
    reaction between chloroform and sodium methoxide, an example of the Williamson ether synthesis. Trimethyl orthoformate is a useful building block for creating...
    5 KB (385 words) - 09:58, 14 May 2025
  • Thumbnail for Diethyl ether
    Diethyl ether can be prepared both in laboratories and on an industrial scale by the acid ether synthesis. The dominant use of diethyl ether is as a solvent...
    27 KB (2,505 words) - 14:19, 12 May 2025
  • Ether cleavage refers to chemical substitution reactions that lead to the cleavage of ethers. Due to the high chemical stability of ethers, the cleavage...
    5 KB (625 words) - 18:59, 23 January 2024
  • Thumbnail for Alcohol (chemistry)
    hydroxide) are powerful bases and nucleophiles (e.g., for the Williamson ether synthesis) in this solvent. In particular, RO− or HO− in DMSO can be used...
    35 KB (3,739 words) - 08:28, 11 May 2025
  • Thumbnail for Ethanol
    Ethanol (redirect from Synthesis of ethanol)
    the compound C 2H 5−O−C 2H 5 (commonly called "ether" in English, more specifically called "diethyl ether"). According to the Oxford English Dictionary...
    107 KB (10,739 words) - 06:29, 11 May 2025
  • Usually symmetrical ethers are prepared by dehydration of alcohols and unsymmetrical ethers by the Williamson ether synthesis from alkyl halides and...
    1 KB (158 words) - 19:27, 20 January 2025
  • Thumbnail for 12-Crown-4
    12-Crown-4 (category Crown ethers)
    lithium cation. 12-Crown-4 can be synthesized using a modified Williamson ether synthesis, using LiClO4 as a templating cation: (CH2OCH2CH2Cl)2 + (CH2OH)2...
    4 KB (311 words) - 10:55, 1 June 2023
  • propan-1-ol and ethyl methyl ether. They all have the formula C3H8O. It was first synthesized in 1853 by Alexander William Williamson and later produced for...
    33 KB (3,208 words) - 17:01, 11 May 2025
  • Thumbnail for 18-Crown-6
    18-Crown-6 (category Crown ethers)
    Charles J. Pedersen. This compound is prepared by a modified Williamson ether synthesis in the presence of a templating cation: (CH2OCH2CH2Cl)2 + (CH2OCH2CH2OH)2...
    10 KB (990 words) - 22:29, 28 January 2025
  • Thumbnail for Auguste Laurent
    Paris from tuberculosis. Alexander Williamson in England read Laurent's writing, leading to the Williamson Ether Synthesis that confirmed the validity of...
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  • reaction from an epoxide and can be considered a variant of the Williamson ether synthesis. Most of the world's supply of propylene oxide arises via this...
    7 KB (838 words) - 23:18, 10 January 2024
  • generates carbocations, the electrophiles. A laboratory-scale example by the synthesis of neophyl chloride from benzene and methallyl chloride using sulfuric...
    22 KB (2,159 words) - 03:34, 1 March 2025
  • hetero atoms) and three or more donor sites that serve as ligands. Crown ethers and porphyrins are prominent examples. Macrocyclic ligands often exhibit...
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  • Thumbnail for Benzyl alcohol
    solubility in water (4 g/100 mL) and is miscible in alcohols and diethyl ether. The anion produced by deprotonation of the alcohol group is known as benzylate...
    12 KB (1,007 words) - 04:49, 27 February 2025
  • Thumbnail for Phenolates
    rate reaches diffusion control. Alkyl aryl ethers can be synthesized through the Williamson ether synthesis by treating sodium phenolate with an alkyl...
    3 KB (289 words) - 09:07, 21 August 2024
  • MTM ethers and recovered in good yield. To introduce an MTM ether to a hydroxyl group, two methods are mainly used. One is a typical Williamson ether synthesis...
    3 KB (358 words) - 15:39, 19 July 2019
  • Thumbnail for 15-Crown-5
    15-Crown-5 (category Crown ethers)
    for Na+ ions. 15-Crown-5 can be synthesized using a modified Williamson ether synthesis: (CH2OCH2CH2Cl)2 + O(CH2CH2OH)2 + 2 NaOH → (CH2CH2O)5 + 2 NaCl...
    8 KB (613 words) - 15:47, 24 March 2025
  • Thumbnail for SN2 reaction
    group, forming an ether. Reactions such as this, with an alkoxide as the nucleophile, are known as the Williamson ether synthesis. If the substrate that...
    21 KB (2,555 words) - 01:43, 30 April 2025